Journals / Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research) / 2008 / Cilt: 32 - Sayı: 3

The investigation of influence of head and neck radiotherapy on flow rate Ph of saliva

Baş ve boyun radyoterapisinin tükürük akış hızı ve Ph sına olan etkisinin incelenmesi

Pages
71–78
Publication Date
2022-10-17
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: We observed a decrease in the flow rate and pH of the saliva collected from the radiotherapy patients during their treatment.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The aim of the study is to investigate and evalued the effect of head and neck radiotherapy (RT) on the flow rate and pH of saliva of 22 nasopharynx (NF) and 23 larynx(L) carcinoma patients subjected to the radiotheraphy.
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Key Findings & Data:Subjects and Method: Saliva samples which were collected from the patients by parafin stimulation, at three phases of the treatment process (before radiotheraphy, in the middle of the theraphy and at the end of the therapy) were analyzed for pH using Beckman Φ 32/34/50 pH metre” (California USA, 1991).
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Conclusion & Impact:Conclusion: We observed a decrease in the flow rate and pH of the saliva collected from the radiotherapy patients during their treatment.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Aim: The aim of the study is to investigate and evalued the effect of head and neck radiotherapy (RT) on the flow rate and pH of saliva of 22 nasopharynx (NF) and 23 larynx(L) carcinoma patients subjected to the radiotheraphy. Subjects and Method: Saliva samples which were collected from the patients by parafin stimulation, at three phases of the treatment process (before radiotheraphy, in the middle of the theraphy and at the end of the therapy) were analyzed for pH using Beckman Φ 32/34/50 pH metre” (California USA, 1991). The flow rate of the saliva samples were calculated by dividing total collected saliva volume to the sampling time for each patient. The results were evaluated statistically. The measurements of the collected parafin stimulated saliva were performed at three phases of radiotheraphy (before radiotheraphy, in the middle of the theraphy and at the end). Saliva flow rates have been calculated by dividing total sample volume to the sampling time interval for each patient. Results: The flow rate and pH of radiotherapy patients saliva decreased during the radiotherapy, and this decrease continued after the radiotherapy. pH analysis showed that the final pH value following therapy were lower than the initial saliva pH of the patients’ saliva. Conclusion: We observed a decrease in the flow rate and pH of the saliva collected from the radiotherapy patients during their treatment.

Özet

Amaç: Bu çalışmada, baş ve boyun bölgesinden radyoterapi(RT) alan 22 nazofarenks (NF) ve 23 larenks(L) karsinomalı toplam 45 hastanın, parafin ile stimüle edilerek toplanan, toplam tükürük örneklerinde radyoterapi öncesi, radyoterapi sırasında ve radyoterapi bitiminde tükürük akış hızı ve tükürük pH sında meydana gelen değişikliklerin incelenmesi amaçlanmıştır. Bireyler ve Yöntem: Tükürük ölçümleri için parafin ile stimüle edilerek toplanan toplam tükürük örneklerinde, radyoterapinin üç aşamasında (radyoterapiden önce, radyoterapinin ortasında ve sonunda) ölçümler yapılmıştır.Toplanan tükürük örnek hacimlerinin, örnekleme süresine bölünmesiyle her bir örnek için tükürük akış hızları belirlenmiştir.Tükürük örneklerinin pH ölçümleri ise laboratuar tipi “Beckman Φ 32/34/50 pH metre” (California USA, 1991) kullanılarak gerçekleştirilmiştir. Elde edilen ölçüm sonuçları istatistiksel olarak değerlendirilmiştir. Bulgular: Bu ölçümlerin değerlendirilmesinde, nazofarinks ve larinks karsinomalı her iki hasta grubunda, tükürük akış hızlarının, radyoterapi süresince düştüğü ve bu düşüşün radyoterapi bitiminde de devam ettiği görülmüştür. Tükürük pH değerleri için ise, radyoterapi bitimindeki değerlerin başlangıç değerlerine göre düşük olduğu gözlenmiştir. Sonuç: Baş ve boyuna uygulanan radyoterapinin hem tükürük akış hızını hemde tükürük pH sını etkilediği, yani hastalarda tükürük asidik bir özellik kazanırken aynı zamanda miktar ve hızında bir azalma meydana geldiği izlenmiştir.

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Cite This Article

BÜYÜKKÖPRÜ, D., DURAL, S. (2022). The investigation of influence of head and neck radiotherapy on flow rate Ph of saliva. Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research), Cilt: 32 - Sayı: 3, 71–78. https://ajindex.com/articles/528406

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