Journals / Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi / 2019 / Cilt: 25 - Sayı: 2

Risk Factors for Sepsis Following Congenital Heart Surgery

Konjenital Kalp Cerrahisi Sonrası Sepsiste Risk Faktörleri

Pages
89–95
Publication Date
2022-10-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Appropriate preoperativepreparation of patients for surgery, reducing the length of stay in the hospital and in the ICU, andreducing the need for reintubation by extubating the patients for an optimal period, would reduce themortality rate due to sepsis.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: This study aims to evaluate the incidence and risk factors associated with sepsis inpediatric patients who underwent congenital heart surgery.Method: A total of 289 patients were prospectively enrolled in this study.
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Key Findings & Data:Patients were dividedinto two groups according to the Society of Critical Care Medicine (SSCM) diagnostic criteria asGroup I including 28 patients who fulfilled the criteria for sepsis and Group II including 261patients without diagnosis of sepsis.
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Conclusion & Impact:Appropriate preoperativepreparation of patients for surgery, reducing the length of stay in the hospital and in the ICU, andreducing the need for reintubation by extubating the patients for an optimal period, would reduce themortality rate due to sepsis.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: This study aims to evaluate the incidence and risk factors associated with sepsis inpediatric patients who underwent congenital heart surgery.Method: A total of 289 patients were prospectively enrolled in this study. Patients were dividedinto two groups according to the Society of Critical Care Medicine (SSCM) diagnostic criteria asGroup I including 28 patients who fulfilled the criteria for sepsis and Group II including 261patients without diagnosis of sepsis. Demographic information, type of operation, complexity,duration of preoperative hospitalization (>5 days) and intensive care unit (ICU) stay, requirementfor mechanical ventilation (MV), history of pulmonary hypertension (PHT), and requirement foremergency surgery, total cardiopulmonary bypass (CPB) and aortic cross-clamp (ACC) times.During the postoperative period delayed sternal closure, duration of mechanical ventilation, theneed for reintubation, and need for reoperation were also recorded.Results: The incidence of sepsis was 4.74%. The mortality rate in septic patients was 32%. Factorsassociated with sepsis were younger age, low body weight, duration of preoperative hospitalizationand ICU stay, preoperative requirement for MV, palliative and emergency interventions, historyof PHT, prolonged MV, reintubation, and reoperation. Multivariate analysis identified reintubationand duration of MV as the major risk factors for sepsis.Conclusion: Serious infectious problems, such as sepsis, are encountered due to inadequatedevelopment of immune resistance mechanisms in pediatric patients. Appropriate preoperativepreparation of patients for surgery, reducing the length of stay in the hospital and in the ICU, andreducing the need for reintubation by extubating the patients for an optimal period, would reduce themortality rate due to sepsis.

Özet

Amaç: Bu çalışmada konjenital kalp cerrahisi yapılan pediyatrik hastalarda sepsis sıklığı ve sepsis ile ilişkili risk faktörleri değerlendirildi. Yöntem: Bu çalışmaya 289 hasta prospektif olarak alındı. Hastalar, Society of Critical Care Medicine (SSCM) tanı ölçütlerine göre Grup I’de, sepsis kriterlerini sağlayan 28 hasta ve Grup II’de sepsis tanısı almayan 261 hasta olmak üzere 2 gruba ayrıldı. Demografik bilgiler, ameliyat tipi, kompleksite, preoperatif hastanede yatış süresi (> 5 gün) ve yoğun bakım ünitesinde (YBÜ) kalış, mekanik ventilasyon gereksinimi (MV), pulmoner hipertansiyon öyküsü (PHT) ve acil cerrahi girişim gereksinimi, toplam kardiyopulmoner baypas (KPB) ve aortik kros klemp(AKK) süreleri kaydedildi. Postoperatif dönemde gecikmiş sternum kapanması, mekanik ventilasyon süresi, reentübasyon ve reoperasyon gereksinimi kaydedildi. Bulgular: Sepsis insidansı %4.74 idi. Septik hastalarda mortalite oranı %32 idi. Sepsis ile ilişkili faktörler genç yaş, düşük vücut ağırlığı, preoperatif hastanede yatış süresi ve YBÜ kalış süresi, preoperatif MV, palyatif girişimler, acil cerrahi, PHT öyküsü, uzun süreli MV, reentübasyon ve reoperasyon idi. Çok değişkenli analiz, reintubasyon ve entübasyon süresini sepsis için majör risk faktörü olarak tanımlandı Sonuç: Pediatrik hastalarda sepsis gibi ciddi infeksiyon sorunları, bağışıklık mekanizmalarının yetersiz gelişmesi nedeniyle rastlanmaktadır. Ameliyat için hastaların uygun preoperatif hazırlıkları, hastanede ve YBÜ’de kalma sürelerinin azaltılması ve hastaların optimal bir süre için ekstübasyona tabi tutulmasıyla tekrar entübasyon gereksiniminin azaltılması sepsis nedeniyle ölüm oranını azaltacaktır.

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Cite This Article

YURTSEVEN, N., KORUN, O., YAVUZ, S. Ş., YAVUZ, Y., AYDEMİR, N. A. (2022). Risk Factors for Sepsis Following Congenital Heart Surgery. Göğüs Kalp Damar Anestezi ve Yoğun Bakım Derneği Dergisi, Cilt: 25 - Sayı: 2, 89–95. https://ajindex.com/articles/525995

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