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AI InsightThe frequency and peak amplitude of spontanaeous contractions were dose-dependly inhibited by 0.015 mg/ml, 0.030 mg/ml and 0.062 mg/ml levels of gentamicin and l.ll(p
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Abstract
The aim of this study was to investigate of te effects of different doses gentamicin and erythromycin on spontaneous and oxytocin-induced myometrium contractions in rats. The frequency of spontaneous contractions was founded 8.22/10 min and peak amplitude was founded 2.9 g . The frequency and peak amplitude of spontanaeous contractions were dose-dependly inhibited by 0.015 mg/ml, 0.030 mg/ml and 0.062 mg/ml levels of gentamicin and l.ll(p
Özet
Bu çalışma spontan ve oksitosinle indüklenen rat uterus myometriumu kontraksiyonlannm ampîitüt ve frekansı üzerine gentamisin ve eritromisinin farklı dozlarının etkisinin belirlenmesi amacıyla yapıldı. Spontan kontraksiyonlara gentamisinin 0.015 mg/ml, 0.030 mg/ml ve 0.062 mg/ml dozlarının uygulanmasıyla 8.22/10 dk olan frekans ve 2.9 gr olan arnplüt doza bağımlı olarak azaldı ve 0.062 mg/ml dozunda sırasıyla l .11 (pO.OOl) ve 0.70 (p