Journals / Epilepsi / 2021 / Cilt: 27 - Sayı: 2

Febrile Seizures in Idiopathic/Genetic Generalized and Self-Limited Focal Epilepsies

İdiyopatik/Genetik Jeneralize ve Kendini Sınırlayan Fokal Epilepsilerde Febril Nöbetler

Journal
Epilepsi
Pages
113–118
Publication Date
2022-10-17
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Although the distribution of FSs in focal or generalized epilepsy groups (p=0.552) and subtypes of these groups (p=0.701) did not indicate any statistical significance, highest ratios of FS occurrence were found in juvenile myoclonic epilepsy and idiopathic photosensitive occipital lobe epilepsy groups.Conclusion: Gender, family history of epilepsy and FS, onset age of epilepsy, type of epilepsy did not seem as a predictor factor for subsequent epilepsy in the patients with FS otherwise normal children

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Febrile seizure (FS) is the most common form of childhood seizures.
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Key Findings & Data:Comparisons were made for the characteristics of FS.Results: Among 320 patients with the diagnosis of focal or generalized epilepsy with presumed genetic cause, FSs were present in 14.7% (n=47) of them without gender preponderance.
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Conclusion & Impact:Although the distribution of FSs in focal or generalized epilepsy groups (p=0.552) and subtypes of these groups (p=0.701) did not indicate any statistical significance, highest ratios of FS occurrence were found in juvenile myoclonic epilepsy and idiopathic photosensitive occipital lobe epilepsy groups.Conclusion: Gender, family history of epilepsy and FS, onset age of epilepsy, type of epilepsy did not seem as a predictor factor for subsequent epilepsy in the patients with FS otherwise normal children
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Febrile seizure (FS) is the most common form of childhood seizures. Furthermore, idiopathic/generalized and focal/self-limited epilepsies present at the similar age-range. They usually have a favorable outcome. This study was conducted to investigate the prevalence and demographic profile of FS in patients with idiopathic/generalized and focal/self-limited epilepsies.Methods: This retrospective study included all of the patients with normal developmental assessments who were admitted to our outpatient clinic with idiopathic/generalized and focal/self-limited epilepsy. The data were collected from their medical and electroencephalogram records. The patients were subgrouped according to their syndromes and the presence of FS. Comparisons were made for the characteristics of FS.Results: Among 320 patients with the diagnosis of focal or generalized epilepsy with presumed genetic cause, FSs were present in 14.7% (n=47) of them without gender preponderance. Self-limited focal epilepsy was present in 232 children (72.5%). The mean age of epilepsy onset was 7.97±3.38 years (range: 1–18 years). Although the distribution of FSs in focal or generalized epilepsy groups (p=0.552) and subtypes of these groups (p=0.701) did not indicate any statistical significance, highest ratios of FS occurrence were found in juvenile myoclonic epilepsy and idiopathic photosensitive occipital lobe epilepsy groups.Conclusion: Gender, family history of epilepsy and FS, onset age of epilepsy, type of epilepsy did not seem as a predictor factor for subsequent epilepsy in the patients with FS otherwise normal children

Özet

Amaç: Febril nöbet (FN) çocukluk çağı döneminin en sık görülen nöbet tipidir. İdiyopatik/jeneralize ve fokal/ kendini sınırlayan nöbetler de aynı yaş grubunda izlenmektedir. Genellikle iyi seyirlidirler. Bu çalışma idiyopatik/jeneralize ve fokal/ kendini sınırlayan epilepsileri olan hastalarda FN prevalansı ve demografik profili araştırmak amacıyla yapılmıştır.Gereç ve Yöntem: Bu geriye dönük çalışmaya polikliniğimize başvurmuş, gelişimsel değerlendirmeleri normal olan idiyopatik/jeneralize ve fokal/ kendini sınırlayan epilepsileri olan hastalar dahil edildi. Veriler hastaların tıbbi ve EEG kayıtlarından toplandı. Hastalar sendromlarına ve FN varlığına göre alt gruplara ayrıldı. Karşılaştırmalar FN özelliklerine göre yapıldı.Bulgular: Fokal ya da olası genetik nedenli jeneralize epilepsi tanılı 320 hasta arasında, FN’ler cinsiyet üstünlüğü olmaksızın %14.7 (n=47) hastada mevcuttu. Kendini sınırlayan fokal epilepsi 232 çocukta (%72.5) mevcuttu. Epilepsi başlangıç ortalama yaşı 7.97±3.38 yıldı (1–18 yıl). FN’lerin fokal ya da jeneralize epilepsi grupları (p=0.552) ya da bu grupların alt tipleri (p=0.701) içindeki dağılımı istatiksel anlamlılık göstermemekle birlikte, FN varlığı en yüksek oranla jüvenil miyoklonik epilepsi ve idiyopatik fotosensitif oksipital lob epilepsi gruplarında bulundu.Sonuç: Cinsiyet, FN ya da epilepsi aile öyküsü, epilepsi başlangıç yaşı, epilepsi tipi FN dışında normal olan çocuklarda ortaya çıkacak epilepsi için belirleyici bir faktör olarak görünmemektedir.

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Cite This Article

İNAN, R., NALBANTOĞLU, M., YAVLAL, F., TÜMAY, F. B., DEMİRBİLEK, V. (2022). Febrile Seizures in Idiopathic/Genetic Generalized and Self-Limited Focal Epilepsies. Epilepsi, Cilt: 27 - Sayı: 2, 113–118. https://ajindex.com/articles/501589

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