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Journals / Epilepsi / 2019 / Cilt: 25 - Sayı: 3

Malformations and Neonatal Problems in Babies of Mothers with Epilepsy: What are the Possible Problems in Women with Epilepsy during Pregnancy?

Epilepsi Tanısı Olan Annelerden Doğan Bebeklerde Malformasyonlar ve Neontalojik Sorunlar: Epilepsi Tanısı Olan Kadınların Gebeliği Hangi Sorunlara Gebe?

Dilek KAHVECİOĞLU
Selda KESKİN GÜLER
Journal
Epilepsi
Pages
147–154
Publication Date
2022-11-04
DOI
—
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The study group consisted of PW with epilepsy (PWWE)(mean age: 27.6 years; n=89), and the control group comprised PW without epilepsy (mean age:27.5 years; n=80).Results: In the PWWE, unintended pregnancy was found to be higher (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: This study aims to investigate the effects of epilepsy and its treatment on maternal and fetal outcomes during pregnancy.Methods: This study was designed as a retrospective observational case-control study.
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Key Findings & Data:One hundred sixty-nine pregnant women (PW) and their newborns wereincluded.
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Conclusion & Impact:The study group consisted of PW with epilepsy (PWWE)(mean age: 27.6 years; n=89), and the control group comprised PW without epilepsy (mean age:27.5 years; n=80).Results: In the PWWE, unintended pregnancy was found to be higher (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: This study aims to investigate the effects of epilepsy and its treatment on maternal and fetal outcomes during pregnancy.Methods: This study was designed as a retrospective observational case-control study. One hundred sixty-nine pregnant women (PW) and their newborns wereincluded. The study group consisted of PW with epilepsy (PWWE)(mean age: 27.6 years; n=89), and the control group comprised PW without epilepsy (mean age:27.5 years; n=80).Results: In the PWWE, unintended pregnancy was found to be higher (p

Özet

Amaç: Epilepsi varlığının ve tedavisinin gebelik boyunca maternal ve fetal sonuçlarının incelenmesi amaçlandı. Gereç ve Yöntem: Çalışma geriye dönük gözlemsel olgu-kontrol çalışması olarak tasarlandı. Çalışmaya 169 doğum yapmış kadın ve bu kadınlardan doğan bebekleri alındı. Olgu grubu olarak yaş ortalaması 27.6 epilepsi tanısı olan gebe kadın (n=89) ve kontrol grubu olarak yaş ortalaması 27.5 olan epilepsi olmayan kadın (n=80) dahil edildi. Bulgular: Olgu grubunda istenmeyen gebelik daha fazlaydı (p

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Cite This Article

KAHVECİOĞLU, D., GÜLER, S. K. (2022). Malformations and Neonatal Problems in Babies of Mothers with Epilepsy: What are the Possible Problems in Women with Epilepsy during Pregnancy?. Epilepsi, Cilt: 25 - Sayı: 3, 147–154. https://ajindex.com/articles/650082

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References (13)

  1. Hernández-Díaz S, Smith CR, Shen A, Mittendorf R, Hauser WA, Yerby M, et al. Comparative safety of antiepileptic drugs during pregnancy. Neurology 2012;78(21):1692–9
  2. Morrow J, Russell A, Guthrie E, Parsons L, Robertson I, Waddell R, et al. Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register. J Neurol Neurosurg Psychiatry 2006;77(2):193–8
  3. Tomson T, Battino D, Bonizzoni E, Craig J, Lindhout D, Perucca E, et al. Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry. Lancet Neurol 2018;17(6):530–8
  4. Koc G, Guler SK, Karadas O, Yoldas T, Gokcil Z. Fetal safety of levetiracetam use during pregnancy. Acta Neurol Belg 2018;118(3):503–8
  5. Schachter SC. Risks associated with epilepsy and pregnancy. UpToDate. Available at: https://www.uptodate.com/contents/ risks-associated-with-epilepsy-and-pregnancy. Accessed August 08, 2018
  6. MacDonald SC, Bateman BT, McElrath TF, Hernández-Díaz S. Mortality and morbidity during delivery hospitalization among pregnant women with epilepsy in the United States. JAMA Neurology 2015;72(9):981–8
  7. Viale L, Allotey J, Cheong-See F, Arroyo-Manzano D, Mccorry D, Bagary M, et al. Epilepsy in pregnancy and reproductive outcomes: a systematic review and meta-analysis. Lancet 2015;386(10006):1845–52
  8. Kahvecioğlu D, Tatar Aksoy H, Keskin Güler S, Yılmaz A, Çalışkan Ş, Alioğlu B. Neonatal Outcomes of Epileptic Mothers’ Infants in the Tertiary Level Of Neonatal Intensive Care Unit: Results from Single Center. [Article in Turkish]. İKSST Derg 2018;10(2):75–80
  9. Edey S, Moran N, Nashef L. SUDEP and epilepsy‐related mortality in pregnancy. Epilepsia 55(7):e72–e4
  10. Fisher RS, Cross JH, D’Souza C, French JA, Haut SR, Higurashi N, et al. Instruction manual for the ILAE 2017 operational classification of seizure types. Epilepsia 2017;58(4):531–42
  11. EUROCAT (2005) EUROCAT Guide 1.3 and reference documents, instructions for the registration and surveillance of congenital anomalies. Available at: http://www.eurocat.ulster.ac.uk/pdf/ EUROC AT-Guide-1.3.pdf. Accessed Dec 23, 2017
  12. Aurlien D, Larsen JP, Gjerstad, L, Taubøll E. Increased risk of sudden unexpected death in epilepsy in females using lamotrigine: A nested, case‐control study. Epilepsia 2012;53(2):258–66
  13. Singh P, Singh M, Cugati G, Singh AK. Effect of epilepsy on female fertility and reproductive abnormal