Journals / Dicle Tıp Dergisi / 2018 / Cilt: 45 - Sayı: 4

Assessment of long term prognostic value of admission vitamin D level in patients with acute STEMI undergoing primary percutaneous coronary intervention

Primer perkutan girişim uygulanan akut STEMI hastalarda başvuru D vitamini düzeyinin uzun dönem prognostik değeri

Pages
369–377
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Cardiovascular mortality was found to be significantly higher in the low vitamin-Dgroup as compared to the high group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Vitamin-D status is very important for optimal function of human body especially cardiovascular system.
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Key Findings & Data:The study patients were divided into 2 groups according totheir vitamin-D levels as follows: High vitamin-D group (n=80) and Low vitamin-D group (n=77).
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Conclusion & Impact:Cardiovascular mortality was found to be significantly higher in the low vitamin-Dgroup as compared to the high group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Vitamin-D status is very important for optimal function of human body especially cardiovascular system. The aim of thisstudy was to investigate the long term prognostic value of admission vitamin D level in acute ST-segment elevation myocardialinfarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI).Methods: One hundred fifty seven consecutive patients, who were admitted to a training and research hospital with a diagnosis ofSTEMI and underwent PPCI, were recruited in this prospective study. The study patients were divided into 2 groups according totheir vitamin-D levels as follows: High vitamin-D group (n=80) and Low vitamin-D group (n=77). The severity of coronary arterydisease (CAD) was assessed with calculation of the SYNTAX score.Results: There were significant negative correlations between Vitamin-D level and SYNTAX score, serum glucose, and gender, but apositive correlation with hemoglobin level. Cardiovascular mortality was found to be significantly higher in the low vitamin-Dgroup as compared to the high group (p

Özet

Amaç: Vitamin-D, insan vücudunda özellikle kardiyovasküler sistemin işlevi için çok önemlidir. Bu çalışmanın amacı, primer perkütan koroner girişim (PPCI) uygulanan akut ST-segment yükselmeli miyokard infarktüsünde (STEMI), hastane başvurusu sırasındaki D vitamini düzeyinin uzun dönem prognostik değerini araştırmaktı. Yöntemler: Bu prospektif çalışmada, eğitim ve araştırma hastanesine STEMI tanısı ile başvuran ve PPCI uygulanan ardışık 157 hasta alındı. Çalışma hastaları başvuru vitamin-D düzeylerine göre 2 gruba ayrıldı: Yüksek vitamin-D grubu (n = 80) ve düşük vitamin-D grubu (n = 77). Koroner arter hastalığının şiddeti SYNTAX skoru ile hesaplandı. Bulgular: Vitamin-D düzeyi ile SYNTAX skoru, serum glikozu ve cinsiyet arasında anlamlı negatif korelasyon vardı, fakat hemoglobin düzeyi ile pozitif korelasyon vardı. Kardiyovasküler mortalite, düşük vitamin-D grubunda, yüksek gruba göre anlamlı olarak daha yüksek bulundu (p

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Cite This Article

IŞIKSAÇAN, N., KÖKTÜRK, U., GÜL, M., ÇAKMAK, H. A., TÜREN, S., TOSU, A. R., SATILMISOĞLU, M. H., KARAKAYALI, M., YILMAZ, E. (2022). Assessment of long term prognostic value of admission vitamin D level in patients with acute STEMI undergoing primary percutaneous coronary intervention. Dicle Tıp Dergisi, Cilt: 45 - Sayı: 4, 369–377. https://ajindex.com/articles/487426

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References (10)

  1. Lee JH, O'Keefe JH, Bell D, et al. Vitamin D deficiency an important, common, and easily treatable cardiovascular risk factor?.J Am Coll Cardiol. 2008; 52: 1949-56. Li YC. Vitamin D regulation of the renin-angiotensin system. J Cell Biochem. 2003; 88: 327–31.
  2. Ortega A, Pérez de Prada MT, Mateos-Cáceres PJ, et al. Effect of parathyroidhormone- related protein on human platelet activation. Clinical Science. 2007; 113: 319–27.
  3. Pittas AG, Lau J, Hu FB, et al. The role of vitamin D and calcium in type 2 diabetes: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2007; 92: 2017–29. Lee JH1, Gadi R, Spertus JA, el al. Prevalence of vitamin D deficiency in patients with acute myocardial infarction. Am J Cardiol. 2011; 107: 1636-8. Holick MF. Vitamin D deficiency. N Engl J Med. 2007; 357: 266-81.
  4. Review. Zittermann A, Kuhn J, Dreier J, et al. Vitamin D status and the risk of major adverse cardiac and cerebrovascular events in cardiac surgery. Eur Heart J. 2013; 34: 1358-64. Wang TJ1, Pencina MJ, Booth SL, et al. Vitamin D deficiency and risk of cardiovascular disease. Circulation. 2008; 117: 503-11.
  5. Khalili H, Talazaz AH, Salarifar M. Serum vitamin D concentration status and its correlation with early biomarkers of remodeling following acute myocardial infarction. Clinical Res Cardiology. 2012; 101: 321–7.
  6. Pilz S, März W, Wellnitz B, et al. Association of Vitamin D deficiency with heart failure and sudden cardiac death in a large cross sectional study of patient referred for coronary angiography. J Clin Endocrinol Metab. 2008; 93: 3927–35.
  7. De Metrio M, Milazzo V, Rubino M, et al. Vitamin D plasma levels and in-hospital and 1-year outcomes in acute coronary syndromes: a prospective study. Medicine (Baltimore). 2015; 94: e857. Correia LC1, Sodré F, Garcia G, et al. Relation of severe deficiency of vitamin D to cardiovascular mortality during acute coronary syndromes. Am J Cardiol. 2013; 111: 324-7.
  8. Naesgaard PA, León De La Fuente RA, Nilsen ST, et al. Serum 25 (OH) D is a 2-year predictor of all-cause mortality, cardiac death and sudden cardiac death in chest pain patients from Northern Argentina. PLoS One. 2012; 7: e43228. Ünal T,N Çayır A, Kaya A. Is low serum 25(OH) vitamin D a risk factor for childhood pneumonias?. Dicle Medical Journal. 2012; 39: 531-5.
  9. Demer LL, Hsu JJ, Tintut Y. Steroid Hormone Vitamin D: Impliations for Cardiovascular Disease. Circ Res. 2018; 22: 1576-85.
  10. Kilkkinen A, Knekt P, Aro A, et al. Vitamin D status and the risk of cardi