Journals / Arşiv Kaynak Tarama Dergisi / 2014 / Cilt: 23 - Sayı: 1

Thrombotic Microangiopathy Associated with Pediatric Transplantation

Çocukluk Çağında Transplantasyon İlişkili Trombotik Mikroanjiyopati

Pages
137–147
Publication Date
2014-10-30
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Even though thrombotic microangiopathy is considered by transplantation physician recently, adequate prospective multi-center studies and broad serial cases are not presented yet.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Transplant-associated thrombotic microangiopathy is a bothersome complication in terms of morbidity and mortality after allogeneic stem cell transplantation.
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Key Findings & Data:It is believed that the endothelial injury causes to thrombotic microangiopathy, but the pathogenesis is not known completely.
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Conclusion & Impact:Even though thrombotic microangiopathy is considered by transplantation physician recently, adequate prospective multi-center studies and broad serial cases are not presented yet.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:trombotik mikroanjiopati · hematopoetik kök hücre nakli · çocukluk çağı

Abstract

Transplant-associated thrombotic microangiopathy is a bothersome complication in terms of morbidity and mortality after allogeneic stem cell transplantation. It is believed that the endothelial injury causes to thrombotic microangiopathy, but the pathogenesis is not known completely. Although there is a consensus about diagnostic criteria, there is no concurrence for the treatment particularly. Even though thrombotic microangiopathy is considered by transplantation physician recently, adequate prospective multi-center studies and broad serial cases are not presented yet.

Özet

Transplant ilişkili trombotik mikroanjiopati, hematopoetik kök hücre nakli sonrası morbidite ve mortalite açısından oldukça can sıkıcı bir komplikasyon olarak karşımıza çıkmaktadır. Olayı endotel hasarının başlattığına inanılmakla birlikte patogenez tam olarak bilinmemektedir. 2007 yılında tanı kriterleri açısından fikir birliği sağlanmasına rağmen, özellikle tedavi konusunda henüz bir fikir birliği bulunmamaktadır. Son yıllarda transplant hekimleri tarafından bu klinik komplikasyon daha fazla akıllara gelmekle birlikte, henüz yeterli prospektif, çok merkezli ve geniş olgu serilerinin yer aldığı çalışmalar bulunmamaktadır.

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Cite This Article

ERBEY, F. (2014). Thrombotic Microangiopathy Associated with Pediatric Transplantation. Arşiv Kaynak Tarama Dergisi, Cilt: 23 - Sayı: 1, 137–147. https://ajindex.com/articles/466138

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References (6)

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