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Journals / Bezm-i Alem Valide Sultan SSK Vakıf Gureba Eğitim Hastanesi Derg. / 2005 / Cilt: 3 - Sayı: 1

The CRP and fibrinogen levels in patients with standart OGTT of diagnosed type 2 diabetes mellitus

Tip 2 diyabet teşhisi için standart oral glukoz tolerans testi (OGTT) yapılan hastalarda C-reaktif protein (CRP) ve fibrinojen düzeyleri

Ahmet Rıza URAS
Mehmet TOSUN
Ahmet KOZAN
Emin Savaş KILAVUZ
İsmet BEYCAN
Pages
20–24
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was significant relations between CRP and fibrinogen levels in persons who were insuline resistance according to HOMA index (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In recent years, it was reported that there was relations between chronic sub clinic inflammation and insulin resistance.
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Key Findings & Data:For this purpose; according to the OGTT result, we compared serum CRP and fibrinogen level with glucose and insulin resistance in patients who had type 2 DM or impaired OGTT.
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Conclusion & Impact:There was significant relations between CRP and fibrinogen levels in persons who were insuline resistance according to HOMA index (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In recent years, it was reported that there was relations between chronic sub clinic inflammation and insulin resistance. For this purpose; according to the OGTT result, we compared serum CRP and fibrinogen level with glucose and insulin resistance in patients who had type 2 DM or impaired OGTT. Also we compared serum CRP and fibrinogen level in patients who were obese and non-obese and who had insulin resistance and normo insulin action. Study design: This study was made as descriptive one in which 87 persons included Material & methods: We selected 87 persons who came our laboratory to be applied 75 gr. OGTT. According to the BMI, we classified the persons as obese or non-obese. Also according to the OGTT result, we classified the persons as DM, impaired OGTT or normal. With using HOMA index, we grouped persons as hading insuline resistance or nor­mal. Results: In selected all persons, we found significant rela­tions between fasting first and second hours glucose level with CRP and fibrinogen level (p0,05). In obese and non-obese there was significant relations between CRP levels (p0,05). There was significant relations between CRP and fibrinogen levels in persons who were insuline resistance according to HOMA index (p

Özet

Amaç: Son yıllarda kronik subklinik inflamasyon insülin direnci ile ilişkilendirilmektedir. Bu amaçla OGTT sonucu­na göre Tip 2 Diyabet ya da OGTT bozulmuş hastalardaki CRP ve fibrinojen düzeyleri ile glukoz ve insülin düzeyleri arasındaki korelatif ilişkiyi araştırdık. Ayrıca bu çalışmada obez olan ve olmayan hastalarla; insülin direnci olan hasta­lar ve insülin direnci olmayan hastaları CRP ve fibrinojen düzeyleri bakımından birbirleriyle karşılaştırıldı. Çalışma düzeni: Bu çalışma 87 hastada yapılan tanım­layıcı araştırma olarak tasarlanmıştır. Gereç ve yöntem: Çalışmamıza Tip 2 diyabet teşhisi konulması amacıyla 75 gr.lık OGTT yapılmak üzere labo­ratuarımıza gönderilen 87 hastayı aldık. Bu hastaları BMI ne göre obez ve obez olmayanlar olarak sınıflandırdık. Hastaları OGTT'ne göre normal, Bozulmuş Glukoz Toleransına sahip veya Diyabetli olarak iki gruba ayırdık. HOMA indeksini kullanarak insülin direnci gelişmiş hasta­larla insülin direnci gelişmemiş hastaları gruplandırdık Bulgular: Çalışmaya katılan bütün hastaların açlık birinci ve ikinci saat glukoz düzeyleri ile CRP ve fibrinojen düzey­leri arasında anlamlı bir korelatif ilişki saptandı (p0.05). Obez hastalarla obez olmayan hastaları CRP ve fibrinojen düzey­leri bakımından birbirleri ile kıyasladığımızda CRP düzey­leri bakımından iki grup arasında anlamlı bir fark tespit edildi (p0.05). Yine HOMA indeksine göre insülin direnci gelişmiş olan hasta grupları ile bu indekse göre insülin direnci gelişmemiş olan hastalar arasında CRP düzeyleri ve fibrinojen düzeyleri bakımından iki grup arasında anlamlı bir fark tespit edildi (p

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Cite This Article

URAS, A. R., TOSUN, M., KOZAN, A., KILAVUZ, E. S., BEYCAN, İ. (2022). The CRP and fibrinogen levels in patients with standart OGTT of diagnosed type 2 diabetes mellitus. Bezm-i Alem Valide Sultan SSK Vakıf Gureba Eğitim Hastanesi Derg., Cilt: 3 - Sayı: 1, 20–24. https://ajindex.com/articles/464183

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