SavedAdd your journal

Journals / Bezm-i Alem Valide Sultan SSK Vakıf Gureba Eğitim Hastanesi Derg. / 2005 / Cilt: 3 - Sayı: 2

Assessment of platelet count and mean platelet volume (MPV) in diagnosis of neonatal sepsis

Neonatal sepsis tanısında trombosit sayısı ve ortalama trombosit hacmi (OTH)'nin değerlendirilmesi

Emin ÖZKAYA
Aksoy Meliha OKAN
Nevin CAMBAZ
Muhammed GEYİK
Fatih METE
Pages
86–90
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There were significant dif- ferences between case group and control group (p

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To asses platelet counts and mean platelet vol- umes in neonates with late onset sepsis and compare to healthy neonates.
📊
Key Findings & Data:Case group included 36 neonates with late onset sepsis.
💡
Conclusion & Impact:There were significant dif- ferences between case group and control group (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To asses platelet counts and mean platelet vol- umes in neonates with late onset sepsis and compare to healthy neonates. Study design: Cross -sectional study Material and methods: Two groups of neonates were stud- ied. Case group included 36 neonates with late onset sepsis. Control group included 36 healthy neonates. In this study, patients were evaluated acording to the history, clinical and laboratory findings. In laboratory heamoculture, cerebro spinale fluid culture, leucocyte, platelet and mean platelet volume were studied. Results: Case group's platelet counts 158.8±107.4, OTH 11.4±1.0fL, control group's platelet counts 277±90.5, OTH 8.8±0.6 fL. were detected. There were significant dif- ferences between case group and control group (p

Özet

Amaç: Yenidoğan geç sepsisi nedeniyle takip edilen yenidoğan bebeklerde trombosit sayısı ve ortalama trombosit hacmi (OTH) ölçülüp bu değerler sağlıklı yenidoğan bebeklerdeki değerlerle karşılaştırıldı. Çalışma düzeni: Kesitsel çalışma yapıldı. Gereç ve yöntem: İki grup çalışmaya dahil edildi. Vaka grubuna 36 yenidoğan, kontrol grubuna da 36 yenidoğan bebek alınmıştır. Çalışmada hastadan alınan anamnez bilgileri, klinik ve laboratuvar bulguları değerlendirildi. Laboratuvarda hastaların kan ve beyin omurilik sıvısı kültürleri, lökosit, trombosit, ortalama trombosit hacimleri, C-reaktif proteinlerine bakıldı. Bulgular:Vaka grubunda trombosit sayısı 158.8±107.4, OTH 11.4±1.0 femtolitre (fL), kontrol grubunda trombosit sayısı 277±90.5, OTH 8.8±0.6fL. olarak bulundu. Aralarındaki fark istatiksel olarak anlamlıydı (p

🔖

Cite This Article

ÖZKAYA, E., OKAN, A. M., CAMBAZ, N., GEYİK, M., METE, F. (2022). Assessment of platelet count and mean platelet volume (MPV) in diagnosis of neonatal sepsis. Bezm-i Alem Valide Sultan SSK Vakıf Gureba Eğitim Hastanesi Derg., Cilt: 3 - Sayı: 2, 86–90. https://ajindex.com/articles/464167

References (1)

  1. Gomella TL. Neonatal sepsis, A Lange Clinical Manuel Neonatology, fourth edition. Appleton and Lange USA 1999; 408-414. 2-Ovalı F. Yenidoðan sepsisi, Neonatoloji, Dağoğlu T, editör. Nobel Tıp Kitabevleri, İstanbul 2000: 679-95. 3-Çoban A. Yenidoğan Enfeksiyonları, Pediatri, Neyzi O, Ertuğrul T, editörler. Nobel Tıp Kitabevi, İstanbul 2002; 431- 43. 4-Lott JW, Neonatal bacterial sepsis. Crit Care Nurs Clin North Am 2003;15:35-46. 5-Adams- Chapman I, Stoll BJ. Systemic inflamatory response syndrome. Semin Pediatr Ýnfect Dis 2001; 5-16. 6-Colarizi P, Fiorucci P, Caradonna A. Circulating thrombopoietin levels in neonates with infection. Acta Paediatr 1999;88:332-7. 7-Cui YB, Du LZ, Chen YZ. Expression of neutrophil adhesion molecule CD(11b) as an early diagnostic marker for neonatal sepsis. Zhonghua Er Ke Za Zhi 2003;41:348-51. 8-Romagnoli C, Frezza S, Cingolani A. Plasma levels of inter- leukin-6 and interleukin-10 in preterm neonates evaluated for sepsis. Eur J Pediatr 2001;160:345-50. 9-Silveira RC, Procianoy RS. Evaluation of interleukin-6, tumour necrosis factor-alpha and interleukin-1beta for early diagnosis of neonatal sepsis. Acta Paediatr 1999; 88:647-50. 10-Santana Reyes C, Garcia-Munoz F, Reyes D. Role of cytokines (interleukin-1beta, 6, 8, tumour necrosis factor-alpha, and soluble receptor of interleukin-2) and C-reactive protein in the diagnosis of neonatal sepsis. Acta Paediatr 2003;92:221-7. 11-Patrick C.H, Lazarchick J. The effect of bacteremia on automated pletelet measurements in neonates. Am J Clin Pathol 1990; 93: 391-394. 12-Ghosh TK, Khan N, Malik A. Platelet auto-antibodies in septicaemic patients. Indian J Pathol Microbiol. 1999;42:31-5. 13-Bessman JD, Gilmer PR, Gardner FH. Use of mean platelet volume improves detection of platelet disorders. Blood Cells 1985; 11: 127- 135. 14-Colarizi P, Fiorucci P, Caradonna A. Circulating thrombopoietin levels in neonates with infection. Acta Paediatr 1999;88:332-7. 15-Guida JD, Kunig AM, Leef KH, et alo. Platelet count and sepsis in very low birth weight neonates: is there an organism-specific response? Pediatrics. 2003;111(6 Pt 1):1411-5. 16-Ghosh S, Mittal M, Jaganathan G. Early diagnosis of neonatal sepsis using a hematological scoring system. Indian J Med Sci. 2001;55:495-500. 17-O'Connor TA, Ringerk M, Gaddis ML. MPV during staphylococcal sepsis in neonates.Am J Clin Pathol, 1993;99:69-71.