Journals / Bakırköy Tıp Dergisi / 2021 / Cilt: 17 - Sayı: 4

The Relationship Between Prognostic and Organ Failure Scoring Systems Such as APACHE II, SAPS II, MODS, SOFA and GCS and Quantitative Amino Acid Levels in Intensive Care Unit Patients

Yoğun Bakım Ünitesindeki Hastalarda APACHE II, SAPS II, MODS, SOFA ve GKS gibi Prognostik ve Organ Yetmezliği Skorlama Sistemleri ile Serum Amino Asit Düzeyleri Arasındaki İlişki

Pages
334–342
Publication Date
2022-10-11
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Statistical significance level was determined as a p-value of

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: This study aimed to investigate the relationship between the prognostic and organ failure scoring systems and quantitative amino acid levels in patients in the intensive care unit (ICU).
📊
Key Findings & Data:Methods: A total of 45 patients over 45 years old, who were admitted to the ICU, were included in the study.
💡
Conclusion & Impact:Statistical significance level was determined as a p-value of
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: This study aimed to investigate the relationship between the prognostic and organ failure scoring systems and quantitative amino acid levels in patients in the intensive care unit (ICU). Methods: A total of 45 patients over 45 years old, who were admitted to the ICU, were included in the study. Physical examinations of all patients were performed, and blood tests (including serum amino acids) were analyzed. Sequential organ failure assessment (SOFA), multiple organ dysfunction score (MODS), simplified acute physiology score II (SAPS II), acute physiology and chronic health evaluation II (APACHE II), and glasgow coma scale (GCS) scores of patients were calculated. Risk ratios were determined according to the mortality and organ failure scores of patients, and patients were grouped as high-risk and low risk. All these parameters were compared between these groups, and the relationship between amino acid levels and risk scores was evaluated. Statistical significance level was determined as a p-value of

Özet

Amaç: Bu çalışmada yoğun bakım ünitesindeki (YBÜ) hastalarda prognostik ve organ yetmezliği skorlama sistemleri ile serum aminoasit düzeyleri arasındaki ilişki araştırıldı. Gereç ve Yöntem: Çalışmaya 45 yaş üstü herhangi bir nedenden dolayı dahiliye YBÜ’ye interne edilen 45 hasta dahil edildi. Tüm hastaların fizik muayeneleri yapıldı ve kan tetkikleri (kantitatif amino asitler dahil) analiz edildi. Hastaların sıralı organ yetmezliği değerlendirmesi (SOFA), çoklu organ disfonksiyon skoru (MODS), Basitleştirilmiş akut fizyoloji skoru II (SAPS II), akut fizyoloji ve kronik sağlık değerlendirmesi II (APACHE II), ve glasgow koma skalası (GCS) skorları hesaplandı. Kantitatif aminoasit düzeyleri ölçüldü. Hastaların mortalite ve organ yetmezliği skorlarına göre risk oranları belirlendi ve hastalar yüksek riskli ve düşük riskli olarak gruplandırıldı. Tüm parametreler bu gruplar arasında karşılaştırıldı ve amino asit seviyeleri ile risk skorları arasındaki ilişki değerlendirildi. İstatistiksel analizde p

🔖

Cite This Article

Özdil, K., Basat, O., Baygül, A., Basat, S. U., Eker, P., Sivritepe, R., Duygu, A. (2022). The Relationship Between Prognostic and Organ Failure Scoring Systems Such as APACHE II, SAPS II, MODS, SOFA and GCS and Quantitative Amino Acid Levels in Intensive Care Unit Patients. Bakırköy Tıp Dergisi, Cilt: 17 - Sayı: 4, 334–342. https://ajindex.com/articles/459956

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Mickiewicz B, Tam P, Jenne CN, Leger C, Wong J, Winston BW, et al. Integration of metabolic and inflammatory mediator profiles as a potential prognostic approach for septic shock in the intensive care unit. Crit Care 2015;19:11
  2. Levy MM, Artigas A, Phillips GS, Rhodes A, Beale R, Osborn T, et al. Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study. Lancet Infect Dis 2012;12:919-24
  3. Michie HR. Metabolism of sepsis and multiple organ failure. World J Surg 1996;20:460-4
  4. Rosenberg AL. Recent innovations in intensive care unit risk- prediction models. Curr Opin Crit Care 2002;8:321-30
  5. Vente JP, von Meyenfeldt MF, van Eijk HM, van Berlo CL, Gouma DJ, van der Linden CJ, et al. Plasma-amino acid profiles in sepsis and stress. Ann Surg 1989;209:57-62
  6. APACHE II Score Estimates ICU mortality. MDCalc ©2005-2021 Available from: URL:
  7. Sequential Organ Failure Assessment (SOFA) Score Predicts ICU mortality based on lab results and clinical data. MDCalc ©2005- 2021 Available from: URL:https://www.mdcalc.com/sequential- organ-failure-assessment-sofa-score
  8. Multiple Organ Dysfunction Score (MODS) © 2021 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA Available from: https://www.merckmanuals.com/professional/ multimedia/clinical-calculator/clinicalcalculator_en_v48814872
  9. Simplified Acute Physiology Score (SAPS) II Estimates mortality in ICU patients, comparable to APACHE II. MDCalc ©2005-2021 Available from: URL:https://www.mdcalc.com/simplified-acute- physiology-score-saps-ii
  10. Rowley G, Fielding K. Reliability and accuracy of the Glasgow Coma Scale with experienced and inexperienced users. Lancet 1991;337:535-8
  11. Bender DA. Amino Acid Metabolism. John Wiley & Sons, The Atrium Southern Gate Chichester West Sussex UK 2 Jul 2012 Availablefrom:https://books.google.com.tr/books?hl=tr&lr= &id=CLok9jcTFVsC&oi=fnd&pg=PT8&dq=Disturbances+of + a m i n o + a c i d + m e t a b o l i s m & o t s = H 6 V H Q T L o I L & s i g =dJ9SikZwKhOUHYhYqdsw0tRKJ_Q&redir_esc=y#v=onepage&q =Disturbances%20of%20amino%20acid% 20metabolism&f =false
  12. Weil MH, Tang W. From intensive care to critical care medicine: a historical perspective. Am J Respir Crit Care Med 2011;183:1451-3
  13. Christopher KB. Nutritional metabolomics in critical illness. Curr Opin Clin Nutr Metab Care 2018;21:121-5
  14. Faix JD. Biomarkers of sepsis. Cr