Journals / Bakırköy Tıp Dergisi / 2020 / Cilt: 16 - Sayı: 3

Risk Factors Affecting Postoperative Morbidity in Laparoscopic Treatment of Perforated Appendicitis, a Single- Center Experience

Perfore Apandisitlerin Laparoskopik Tedavisinde Morbidite Gelişimi Üzerine Etkili Risk Faktörleri, Tek Merkez Deneyimi

Pages
272–279
Publication Date
2022-11-06
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

We think that patients diagnosed withperforated appendicitis should be operated on as early as possible, routinely placing a drain should be avoided, and laparoscopic approachshould be preferred as much as possible to reduce the morbidity rates.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Postoperative morbidity may occur more in laparoscopic treatment of perforated appendicitis than simple appendicitis.
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Key Findings & Data:In this study,we aimed to investigate the risk factors affecting the development of morbidity in laparoscopic treatment of perforated appendicitis.Method: The files of patients who underwent laparoscopic appendectomy due to perforated appendicitis were analysed retrospectively.
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Conclusion & Impact:We think that patients diagnosed withperforated appendicitis should be operated on as early as possible, routinely placing a drain should be avoided, and laparoscopic approachshould be preferred as much as possible to reduce the morbidity rates.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Postoperative morbidity may occur more in laparoscopic treatment of perforated appendicitis than simple appendicitis. In this study,we aimed to investigate the risk factors affecting the development of morbidity in laparoscopic treatment of perforated appendicitis.Method: The files of patients who underwent laparoscopic appendectomy due to perforated appendicitis were analysed retrospectively. Findingof perforation has been documented by surgeons who performed surgery. Information on the patients such as age, gender, Charlson ComorbidityIndex (CCI), body mass index (BMI), ASA scores, symptom onset time, time between hospital admission and surgery, surgical findings, perforationsites, type of surgery, stump closure materials, white blood cell counts, pathology results and postoperative morbidities were recorded. Data werecompared between patients with and without morbidity, and multivariate regression analysis of variables with significant p value wasperformed.Results: The rate of morbidity development in laparoscopic treatment of perforated appendicitis was 22.14% (66/298). In multivariate regressionanalysis, the onset of symptoms longer than 72 hours, proximal perforation, grade 5 diffuse peritonitis in surgical finding according to DiseaseSeverity Score (DSS), conversion from laparoscopic to open surgery and gangrene or necrosis in histopathological finding were found to beeffective risk factors in the development of morbidity. (p=0.013, odds ratio=1,455, p=0.010, odds ratio=2.009, p=0.002, odds ratio=2.648, p=0.014, odds ratio=6.537, p=0.003, odds ratio=1.843; respectively).Conclusion: The development of postoperative morbidity in laparoscopic treatment of perforated appendicitis is associated with late admissiondevelopment of diffuse peritonitis, conversion to open surgery, proximal perforation and presence of necrosis. According to odds ratio, the riskfactor with the highest probability of developing morbidity was found to be conversion to open surgery. We think that patients diagnosed withperforated appendicitis should be operated on as early as possible, routinely placing a drain should be avoided, and laparoscopic approachshould be preferred as much as possible to reduce the morbidity rates.

Özet

Amaç: Perfore apandisitlerin laparoskopik tedavisinde postoperatif morbidite basit apandisitlere göre daha fazla gelişmektedir. Biz bu çalışmada, perfore apandisitlerin laparoskopik tedavisinde morbidite gelişimine etki eden risk faktörlerini araştırmayı amaçladık. Yöntem: Perfore apandisit nedeniyle laparoskopik apendektomi yapılan hastaların dosyaları retrospektif olarak incelendi. Perforasyon bulgusu ameliyatı yapan cerrahlar tarafından belgelenmiştir. Çalışmaya dahil edilen hastaların yaşı, cinsiyeti, Charlson Komorbidite Indeksi (CCI), vücut kitle indeksi (VKİ) ASA skorları, semptom başlangıç ve hastane başvuru ile ameliyat arasında geçen süreleri, ameliyat bulguları, perforasyon yerleri, ameliyat şekilleri, güdük kapatma materyalleri, lökosit değerleri, patoloji sonuçları ve postoperatif morbiditeleri kayıt altına alındı. Veriler morbidite gelişen ve gelişmeyen hastalarda karşılaştırıldı ve p değeri anlamlı çıkan değişkenlerin multivariate regresyon analizi yapıldı. Bulgular: Perfore apandisitlerin laparoskopik tedavisinde mobidite gelişme oranı %22.14 (66/298) olarak izlenmiştir. Multivariate regresyon analizinde semptom başlangıcının üzerinden 72 saat geçmesi, ameliyat bulgularına göre perforasyon yerinin radiks olması, DSS’ye göre ameliyat bulgusunda grade 5 diffuz peritonit tablosu olması, laparoskopiden açığa dönülmesi ve post operatif histopatolojik bulguda gangren veya nekroz olması post operatif morbidite gelişimi üzerine etkili risk faktörleri olarak bulunmuştur (p=0.013, olasılık oranı=1,455; p=0.010, olasılık oranı=2.009; p=0.002, olasılık oranı=2.648; p=0.014, olasılık oranı=6.537; p=0.003, olasılık oranı=1.843; sırasıyla). Sonuç: Perfore apandisitlerin laparoskopik tedavisinde post operatif morbidite gelişimi geç başvuru, diffüz peritonit gelişimi, açığa dönüş, radiks perforasyonu ve nekroz varlığı ile ilişkilidir. Olasılık oranlarına göre morbidite gelişme ihtimali en yüksek olan risk faktörü açığa dönüş olarak bulunmuştur. Apandisit perforasyonu tanısı alan hastaların olabildiğince erken ameliyat edilmesi, rutin dren yerleştirilmemesi ve morbidite gelişimini önlemek için mümkün olduğunca laparoskopik yaklaşım uygulanması gerektiğini düşünüyoruz.

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Cite This Article

KARABULUT, M., SÜREK, A. (2022). Risk Factors Affecting Postoperative Morbidity in Laparoscopic Treatment of Perforated Appendicitis, a Single- Center Experience. Bakırköy Tıp Dergisi, Cilt: 16 - Sayı: 3, 272–279. https://ajindex.com/articles/648919

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