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Journals / Atatürk Üniversitesi Veteriner Bilimleri Dergisi / 2019 / Cilt: 14 - Sayı: 1

Determination of Possible Potential Biomarker Between Plasma Arginase, Gelsolin and Cystatin C in Sheep Babesiosis: Based on Parasitemia Rate

Koyun Babeziozisinde Plazma Arginaz, Gelsolin ve Sistatin C Arasında Olası Potansiyel Biyobelirteç Tayini: Parazitemi Oranına Göre

Kaveh AZIMZADEH
Mortaza MAHAN
Negar Zamani HERGALANI
Tohid ZAHED
Pages
1–7
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The results indicated significant increase(P

📌 3 Key Takeaways

🎯
Objective & Hypothesis:The aim of this study was to assay arginase activity, gelsolin (GLS) and cystatin c (Cys c) levels and determination ofpotential biomarker in sheep babesiosis.
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Key Findings & Data:After blood sampling from 25infected and same number healthy sheep, above parameters measured in plasma.
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Conclusion & Impact:The results indicated significant increase(P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

The aim of this study was to assay arginase activity, gelsolin (GLS) and cystatin c (Cys c) levels and determination ofpotential biomarker in sheep babesiosis. The Babesia genus as pathogen blood parasites causes economic problems inlivestock management. Many published studies have suggested babesiosis-induced biochemical parameters, but no one havedetermined those parameters alterations and clarification of sensitivity and specificity. Sheep with acute babesiosis wereidentified based on clinical signs and the observation of Piroplasm forms in red blood cells. After blood sampling from 25infected and same number healthy sheep, above parameters measured in plasma. The results indicated significant increase(P

Özet

Bu çalışmanın amacı, koyun babeziosisinde arginaz aktivitesi, gelsolin (GLS) ve sistatin c (Cys c) seviyelerini ve potansiyel biyobelirteç tespitini incelemektir. Patojen kan parazitleri olan Babesia türleri, hayvancılık yönetiminde ekonomik sorunlara neden olur. Yayımlanan birçok çalışmada babeziosis kaynaklı biyokimyasal parametreler önerilmiş, ancak hiç kimse bu parametrelerdeki duyarlılık ve özgüllüğü ve değişiklikleri açıklığa kavuşturmamıştır. Akut babeziosisli koyunlar, kırmızı kan hücrelerinde Piroplazma formlarının görülmesi ve klinik bulgulara göre belirlendi. Yirmibeş adet enfekte ve aynı sayıda sağlıklı koyunlardan alınan kan örneklemesinden sonra, yukardaki parametreler plazmada ölçüldü. Sonuçlar, arginaz ve Cys c'de anlamlı bir artış (P

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Cite This Article

AZIMZADEH, K., MAHAN, M., HERGALANI, N. Z., ZAHED, T. (2022). Determination of Possible Potential Biomarker Between Plasma Arginase, Gelsolin and Cystatin C in Sheep Babesiosis: Based on Parasitemia Rate. Atatürk Üniversitesi Veteriner Bilimleri Dergisi, Cilt: 14 - Sayı: 1, 1–7. https://ajindex.com/articles/455739

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