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Journals / Arşiv Kaynak Tarama Dergisi / 2018 / Cilt: 27 - Sayı: 2

Iron Overload due to Treatment in Childhood Cancers

Çocukluk Çağı Kanserlerinde Tedaviye Bağlı Demir Yükü

Aysu İLHAN YALAKİ
Begül YAĞCI-KÜPELİ
Pages
223–240
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Ferritin level measurement is the easiest and cheapest method for evaluation of iron overload.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Transfusion associated iron overload is an important complication of supportive treatment in children with cancer.
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Key Findings & Data:In patients with solid tumors who are treated with intensive chemotherapy regimens, patients with leukemia, and patients who underwent stem cell transplantation show more transfusion requirement resulting in significant iron overload.
💡
Conclusion & Impact:Ferritin level measurement is the easiest and cheapest method for evaluation of iron overload.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Transfusion associated iron overload is an important complication of supportive treatment in children with cancer. The standart treatment of anemia induced by chemotherapy is erythrocyte transfusion. In patients with solid tumors who are treated with intensive chemotherapy regimens, patients with leukemia, and patients who underwent stem cell transplantation show more transfusion requirement resulting in significant iron overload. Ferritin level measurement is the easiest and cheapest method for evaluation of iron overload.

Özet

Kanser tedavisi sırasında saptanan aneminin şiddeti hastada kullanılan kemoterapi rejimi ve yoğunluğuna bağlıdır. Kemoterapinin indüklediği aneminin standart tedavisi eritrosit süspansiyonu transfüzyonudur. Yoğun tedavi rejimleriyle tedavi edilen solid tümör ve lösemi tanılı hastalarla, hematopoetik kök hücre nakli yapılan hastalarda kullanılan yoğun kemoterapi rejimleri nedeniyle daha sık transfüzyon ihtiyacı; bunun sonucunda da daha fazla demir yükü ortaya çıkmaktadır. Ferritin düzeyi demir yükünün ölçümünde kullanılan en ucuz ve en kolay yöntemdir

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Cite This Article

YALAKİ, A. İ., YAĞCI-KÜPELİ, B. (2022). Iron Overload due to Treatment in Childhood Cancers. Arşiv Kaynak Tarama Dergisi, Cilt: 27 - Sayı: 2, 223–240. https://ajindex.com/articles/449178

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