A case of primary pulmonary histiocytosis-X

Key Findings & Data:High resolution computerized tomography (HRCT) was shown bilateral upper lob anterior segments involved with interstitial, interlober tickness and cysts were diameter about 10mm.

💡

Conclusion & Impact:No found pathologic finding other systems examination as a related eosinophilic granuloma.

🔬Design:Research Article

📍Scope:Comprehensive Sample

⚙️Variables:Domain Parameters

Abstract

Thirty-six years old men admitted to hospital with cough, chest pain, and hemopthysis. Physical examination was revealed clubbing and bilateral inspiratory crackles on the pulmonary basis. On the postero-anterior chest xRay was seen bilateral covering, all lung field reticulonoduler patern. High resolution computerized tomography (HRCT) was shown bilateral upper lob anterior segments involved with interstitial, interlober tickness and cysts were diameter about 10mm. Carbonmonoksid diffusing capacity (DLCO) and percentage of alveolar ventilation (DLCO/VA) were found respectively 15,7 (49%), 69%. Performed open lung biopsy was diagnosed as eosinophilic granuloma. No found pathologic finding other systems examination as a related eosinophilic granuloma.

Özet

Otuzaltı yaşında erkek hasta nefes darlığı, öksürük, göğüs ağrısı ve hemoptizi yakınmaları ile hastaneye başvurdu. Fizik muayenede akciğerlerde bilateral bazallerde inspiratuar railer ve çomak parmak saptandı. Postero-anterior akciğer grafısinde tüm akciğer alanlarını kaplayan bilateral retikülonodüler görünüm, toraks yüksek rezolusyonlu bilgisayarlı tomografisinde (YRBT); Her iki akciğer üst lob anterior segmentlerde interlober interstisyel kalınlaşma ve 10mm çapa ulaşan ince duvarlı multipl küçük kistik lezyonlar mevcuttu. Solunum fonksiyon testlerinde (SFT) hafif restriktif patern, karbonmonoksit diffüzyon kapasites (DLCO) 15,7 (%49) ve alveol ventilasyonuna oranı (DLCO/VA) %69 bulundu. Hastaya yapılan torakotomi ile Eozinofılik granülomun neden olduğu Kronik interstisyel pnömoni tanısı kondu. Diğer sistemlerin taramasında ise eozinofilik granüloma ait patoloji saptanmadı.

🔖

Cite This Article

BAŞER, Y., ULUBAŞ, B., SEZER, Ö. C., DEMİRAĞ, F. (2022). A case of primary pulmonary histiocytosis-X. Anadolu Tıp Dergisi, Cilt: 5 - Sayı: 1, 46–49. https://ajindex.com/articles/438111

References (1)

Akçay N, Eyüpoğlu FÖ, Arıcan A, Demirhan B. Effect of pulse steroid therapy in a patient with Langerhans' cell histiosis. Respirology 2001;6(4):357-360 2)Başay N, Ofluoğlu N, Berktaş B, Özkara Ş. Bir Langerhans Hücreli Granüloma Olgusu. Solunum Hastalıkları 1996;7(2):237-242 3) Colby TV, Lombard C. Histiocytosis-X in the Lung. Hum Pathol 1983;14:847-56 4)Crausman RS, Jennings CA, Tuder RM et al. Pulmonary Histiocytosis-X: Pulmonary function and exercise pathophisiology. Am J Respir crit Care Med 1996; 153:426-35. 5)Dams I, Sieminska A Jassem E, Kobiarska G Jadezuk E, Slominski JM. A case of eosinophilic granüloma localized in the bronchial wall. Pnomol Alergol Pol 1998;66(7-8):422-6 6)Essen S, West W, Sitorius M, Rennard S. Complete Resolution of Roentgenographic Changes in a Patient with Pulmonary Histiocytosis-X. Chest 1990; 98:765-67. 7)Fartoukh M, Humbert M, Capron F et al. Severe pulmonary Hypertension in Histiocytosis-X. Am J Respir Crit Care Med 2000; 161: 216-23 8)Fraser RS, Colman N, Müller N, Pare P. Langerhans' cell Histiocytosis. Diagnosis of Disease of the Chest,4th ed.Phyladelphia: WB Saunders Company 1999;1627-1639 9) King TE, Schwarz MI, Dreisn RE et al. Circulating Immune Complexes an Pulmonary Eosinophilic Granüloma. Ann Med 1979;91:397-9 10) King TE, Crausman RS. Pulmonary Histiocytosis-X. In Fishman AP 3rd ed. Pulmonary Diseases and Disorders. New York: McGraw-Hill, 1998:1163-70 11)Loukides S,Karameris A, Lachanis S, Panagua P, Kalogeropoulos N. Eosinophilic granüloma of the lung presenting as an endobronchial mass. Monaldi Arch Chest Dis 2000; 55(3):709-4 12) McClain K, Weiss RA. Viruses and Langerhans Cell Histiocytosis. Is there a link? BrJ Cancer 1994; 78:34-6 13)Ryu HJ, Olson EJ, Myers J. Other Diffuse Lung Disease.Comprerhensive Respiratory Medicine.In:Albert R, Spiro S, Jett J. London:Hourcourt Brace and Company 1999:49.1-49.8 14) Sadoun D, Voylet F, Valeyre D et al. Bronchogenic Carcinoma in Patients with Pulmonary Histiocytosis-X. Chest 1992;101:1610-3 15) Soler P, Chollet S, Jacque C et al. Immuncytochemical Characterization of Pulmonary Histiocytosis-X Cells in Lung Biopsies. Am J Pathol 1985; 118: 439-51 16) Travis WD, Barok Z, Roun JH et al. Pulmonary Langerhans Cell Granulamatosis. Am J Surg Pathol 1993; 17:971-86