Journals / Tüberküloz ve Toraks / 2015 / Cilt: 63 - Sayı: 4

Storage mite sensitivity and related factors in asthmatic patients

Astımlı hastalarda depo akarı duyarlılığı ve ilişkili faktörler

Pages
226–234
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Besides, respiratory screening spesific IgE, L. destructor spesific IgE was examined in a group of patients who were allergic to storage mites according to prick tests.Results: Prick test results showed that; 115 of the patients were sensitized while 34 of them were not.

📌 3 Key Takeaways

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Objective & Hypothesis:Introduction: The aim of the study was to investigate the storage mite sensitivity and related factors in patients with asthma or asthma and rhinitis.Patients and Methods: 149 patients with asthma or asthma and rhinitis were included to the study.
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Key Findings & Data:Besides, respiratory screening spesific IgE, L. destructor spesific IgE was examined in a group of patients who were allergic to storage mites according to prick tests.Results: Prick test results showed that; 115 of the patients were sensitized while 34 of them were not.
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Conclusion & Impact:Addition of storage mite allergens to the standart prick test panel of patients living in rural area is suitable.
🔬Design:Survey & Empirical Study
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Introduction: The aim of the study was to investigate the storage mite sensitivity and related factors in patients with asthma or asthma and rhinitis.Patients and Methods: 149 patients with asthma or asthma and rhinitis were included to the study. Prick test was performed after addition of Acarus siro (A. siro), Lepidoglyphus destructor (L. destructor), Glycophagus domesticus (G. domesticus) and Tyrophagus putrescentiae (T. putrescentiae) to the standart prick test. Living conditions, smoking history, allergic diseases status, seasonal variations in symptoms were evaluated by a questionnaire. Besides, respiratory screening spesific IgE, L. destructor spesific IgE was examined in a group of patients who were allergic to storage mites according to prick tests.Results: Prick test results showed that; 115 of the patients were sensitized while 34 of them were not. House dust mite sensitivity was detected as mite 58.3%.The storage mite sensitivity for at least one of the studied species was detected in 61.7% of patients. The sensitivity rates were 50.4%, 48.7%, 47%, %40 for A. siro, L. destructor, G. domesticus and T. putrescentiae, respectively. The storage mite sensivity was found higher in the patients from the rural areas (p< 0.05). L. destructor IgE positiveness was detected in 9.1% of the group that antibody levels were examined. Positive reaction was detected for at least one of the storage mite species in %22.7 of the patients who were considered as not sensitized according to the results of the standart prick tests.Conclusion: As a result, storage mites are important allergens in subjects who live in rural areas and close contact with barn, haymow, bin and pantry. Addition of storage mite allergens to the standart prick test panel of patients living in rural area is suitable.

Özet

Giriş: Çalışmamızda astım ve astım ve rinit tanısı almış hastalardaki depo akarı duyarlılığı ve duyarlanmada etkili olan faktörlerin araştırılması amaçlandı.Hastalar ve Metod: Astım ve astım + rinit tanısı bulunan 149 hasta çalışmaya alındı. Standart deri testine depo akarlarından Acarus siro (A. Siro), Lepidoglyphus destructor (L. destructor), Glycophagus domesticus (G. domesticus) ve Tyrophagus putrescentiae (T. putrescentiae) eklenerek uygulandı. Hastaların yaşam koşulları, sigara içme öyküleri, allerjik hastalık öyküleri, semptomların mevsimlerle ilişkisini sorgulayan bir anket uygulandı. Solunum tarama spesifik IgE yanı sıra deri testinde depo akarlarına duyarlılığı olanlar arasından seçilen bir gruba L. destructor spesifik IgE düzeyi ölçümleri yapıldı.Bulgular: Prick test sonuçlarına göre hastaların 115 hastada en az bir allerjene karşı duyarlılık saptanırken, 34 hastada hiçbir allerjene karşı duyarlılık saptanmadı. En az bir depo akarı türüne karşı duyarlılık %61.7 olarak tespit edildi. A. siro %50.4, L. destructor %48.7, G. domesticus %47 ve T. putrescentiae %40 oranında deri testi pozitifliği mevcuttu. Ev tozu akarı duyarlılığı %58.3 olarak tespit edildi. Kırsal alanda yaşayanlarda depo akarı duyarlılığı, kentsel alanda yaşayanlarla karşılaştırıldığında, istatistiksel olarak anlamlı derecede yüksek bulundu (p< 0.05). L. destructor spesifik IgE çalışılan grupta %9.1 oranında L. destructor IgE pozitifliği vardı. Standart deri testi paneline göre duyarlılık saptanmayan olguların %22.7'si en az bir depo akarı türüne deri testi duyarlılığı göstermekteydi.Sonuç: Depo akarları kırsal alanda yaşayanlarla, ahır, samanlık, ambar ve kilerle ilişkili koşullarda yaşayanlarda önemli bir allerjendir. Kırsal alanda yaşayanlarda standart deri testi paneline depo akarlarının eklenmesi uygundur.

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Cite This Article

CANBAKAN, S., MUNGAN, D., BAŞER, Y., AKPINAR, E. E., AKPINAR, S. (2022). Storage mite sensitivity and related factors in asthmatic patients. Tüberküloz ve Toraks, Cilt: 63 - Sayı: 4, 226–234. https://ajindex.com/articles/618563

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References (14)

  1. Platt-Mills TAE. The role of allergens in airway disease. J Allergy Clin Immunol 1998;101:364-66. Bush RK. Indoor allergens, environmental avoidance, and allergic respiratory disease. Allergy Asthma Proc 2008;29:575-9.
  2. Olsson S, Van Hage-Hamsten M. Allergens from house dust and storage mites; similarities and differences, with empha- sis on the storage mite Lepidoglyphus destructor. Clin and Exp Allergy 2000;30:912-19.
  3. Solomon WR, Platts-Mills TAE. Aerobiology and inhalant allergens. In: Middleton E, Reeds CE, Ellis EF, Adkinson NF, Yunginger JW, Busse WW (eds). Allegy, Vol 2. 5th ed. St Louis, Missouri: Mosby-Year Book Inc, 1998:81-99.
  4. Gregory LG, Lloyd CM. Orchestrating house dust mite- associated allergy in the lung. Trends Immunol 2011;32:402- 11. Gaffin JM, Phipatanakul W. The role of indoor allergens in the development of asthma. Curr Opin Allergy Clin Immunol 2009;9:128-35.
  5. Kromquist M, Johansson E, Pershagen G, Johansson SG, van Hage-Hamsten M. Increasing prevalence of asthma over 12 years among dairy farmers on Gotland, Sweden: storage mites remain dominant allergens. Clin and Exp Allergy 1999;29:35-41. Türk Toraks Derneği Astım tanı ve tedavi rehberi 2014 güncellemesi. Turkish Thoracic Journal 2014;15:13-9.
  6. Fernandez- Caldas E, Iraola Calvo V. Mite allergens. Curr Allergy Asthma Rep 2005;5:402-10.
  7. Bavbek S, Çelik G, Ediger D, Mungan D, Sin B, Demirel YS, et al. Severity and associated risk factors in adults asthma patients in Turkey. Ann Allergy Asthma Immunol 2000;85:134-9.
  8. Magnan A, Fourre-Jullian C, Jullian H, Badier M, Lanteume A, Vervloet D, et al. Rhinitis alone or rhinitis plus asthma: What makes the difference? Eur Respir J 1998;12:1073-8.
  9. Gates EH, Platts-Mills TAE. What the pulmonologist needs to know about allergy. Clin in Chest Med 1995;16(Suppl 4):S603-S702. Van Hage-Hamsten M, Johansson SG. Storage mites. Review. Exp Appl Acarol 1992;16:117-28.
  10. Iversen M, Korsgaard J, Hallas T, Dahl R. Mite allergy and exposure to storage mites and house dust mites in farmers. Clin Exp Allegy 1990;20:211-9.
  11. Franz J-Th, Masuuch G, Müsken H, Bergman K-Ch. Mite fauna of German farms. Allergy 1997;52:1233-7.
  12. Marx JJ Jr, Twiggs JT, Ault BJ, Merchant JA, Fernandez-Caldas E. İnhaled aeroallergen and storage mite reactivity in a Wisconsin farmer nested case-control study. Am Rev Respir Dis 1993;147:354-8.
  13. Peden D, Reed CE. Environmental and occupational aller- gies. J Allergy Clin Immunol 2010;125:150-60.
  14. Van Hage-hamsten M, Laggin E, Harfast B, Johansson S