AI Summary & Key Takeaways
AI InsightDevelop¬ment of intracranial tuberculomas despite effective antituberculous drug treatment was attribu¬ted to paradoxical response.
📌 3 Key Takeaways
Abstract
A 24-year-old male patient was referred to our clinic from another hospital with the diagno¬sis ofmiliary tuberculosis. Although he was given effective antituberculosis treatment, some symp¬toms indicating to a central nervous system have disorder appeared. Cranial computed tomog¬raphy (CT) revealed multiple intracranial tuberculomas. Dexamethasone was added to the anti-tuberculous drug regimen. While dexamethasone dose tapered, intracranial lesions progressed radiologically. Dexamethasone dose was increased again and the patient was followed up by se¬rial CT. Intracranial tuberculomas were completely cleared out after steroid therapy. Develop¬ment of intracranial tuberculomas despite effective antituberculous drug treatment was attribu¬ted to paradoxical response.
Özet
Yirmidört yaşında erkek hasta bir başka hastaneden milier tüberküloz tanısı ile hastanemize sevk edildi. Yeterli anti-tüberküloz tedavi başlamamıza rağmen hastada santral sinir sistemi bo¬zukluğuna ait olabilecek yeni semptomlar gelişti. Bilgisayarlı beyin tomografisinde (BBT) mul¬tipl intrakranial tüberkülomalar saptandı ve antitüberküloz tedaviye deksametazon eklendi. Deksametazon dozu azaltıldığında intrakranial lezyonlann radyolojik olarak ilerlediği gözlen¬di. Deksametazon dozu tekrar artırıldı ve hasta seri BBT takibine alındı. Steroid tedavisi sonra¬sı intrakranial tüberkülomalar bütünüyle kayboldu. Etkili antitüberküloz ilaç tedavisine rağmen intrakranial tüberkülomalar gelişmesi paradoksal yanıta bağlandı.