Journals / Anadolu Kardiyoloji Dergisi / 2005 / Cilt: 5 - Sayı: 4

Metabolik sendromlu kadınlarda gizli sol ventrikül disfonksiyonu mu var?

Do female patients with metabolic syndrome have masked left ventricular dysfunction?

Pages
283–288
Publication Date
2022-10-10
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Patients with MS showed LV global dysfunctions compared to healthy subjects (MPI: 0.56±0.12 and 0.46±0.11 respectively, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Metabolic syndrome (MS) is a condition, which is recognized as raising the risk of cardiovascular disease.
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Key Findings & Data:The aim of our study is to estimate the left ventricular functions by atrioventricular plane displacement (AVPD), myocardial performance index (MPI) and conventional methods in patients with MS who were diagnosed according to NCEP (ATP III) criteria.Methods: Fifty-three female patients with MS (mean age 53.1±6.9 years) and 30 healthy female subjects (mean age 52.8±6.3 years, p>0.05) underwent complete echocardiographic assessment.
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Conclusion & Impact:Patients with MS showed LV global dysfunctions compared to healthy subjects (MPI: 0.56±0.12 and 0.46±0.11 respectively, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Metabolic syndrome (MS) is a condition, which is recognized as raising the risk of cardiovascular disease. The aim of our study is to estimate the left ventricular functions by atrioventricular plane displacement (AVPD), myocardial performance index (MPI) and conventional methods in patients with MS who were diagnosed according to NCEP (ATP III) criteria.Methods: Fifty-three female patients with MS (mean age 53.1±6.9 years) and 30 healthy female subjects (mean age 52.8±6.3 years, p>0.05) underwent complete echocardiographic assessment. All of the subjects had no heart and pulmonary diseases. The systolic mitral AVPD was recorded at 4 sites (septal, lateral, anterior, and posterior) by M-mode echocardiography and left ventricle ejection fraction (LVEF) was calculated from the AVPD-mean (EF-AVPD). The LVEF was also established by biplane Simpson’s (EF-2D) and Teichholz’s methods (EF-T). Left ventricular MPI was calculated as (isovolumic contraction time + isovolumic relaxation time) / aortic ejection time by Doppler echocardiography. Results: Patients with MS showed mild left ventricular diastolic dysfunction (DD) in comparison to healthy subjects. The EF-2D and EF-T in patients with MS and healthy subjects were not different significantly and were within normal limits. Patients with MS showed LV global dysfunctions compared to healthy subjects (MPI: 0.56±0.12 and 0.46±0.11 respectively, p

Özet

Amaç: Metabolik sendrom (MS), kardiyovasküler hastalık riskini artırdığı kabul edilen bir durumdur. Bu çalışmanın amacı, NCEP (ATP III) kriterlerine göre MS tanısı konmuş hastalarda, sol ventrikül fonksiyonlarını atriyoventriküler plan yer değişimi (AVPD), miyokardiyal performans indeksi (MPİ) ve konvansiyonel metodlarla değerlendirmektir. Yöntemler: Metabolik sendromlu 53 kadın hasta (ortalama yaş 53.5±6.9 yıl) ve 30 sağlıklı kadın (ortalama yaş 52.7±6.3 yıl, p>0.05) tam ekokardiyografik değerlendirmeye alındı. Olguların hiçbirinde kalp ve akciğer hastalığı yoktu. Sistolik mitral AVPD 4 bölgeden (septal, lateral, anteriyor ve posteriyor) M-mod ekokardiyografi ile ölçüldü ve ortalama AVPD’den sol ventrikül ejeksiyon fraksiyonu (EF) hesaplandı(EF-AVPD). Sol ventrikül EF, ayrıca biplan Simpson (EF-2D) ve Teichholz (EF-T) metodlarıyla da değerlendirildi. Miyokardiyal performans indeksi, Doppler ekokardiyografi ile (isovolümik kontraksiyon zamanı + isovolümik relaksasyon zamanı) / aortik ejeksiyon zamanı) formülünden hesaplandı. Bulgular: Metabolik sendromlu kadınlar, sağlıklı kişilerle kıyaslandığında hafif sol ventrikül diyastolik disfonksiyonu (DD) gösterdiler. Hasta ve kontrol gruplarında EF-2D ve EF-T anlamlı fark oluşturmadı ve normal sınırlardaydı. Metabolik sendromlu hastalar sağlıklı kişilere göre sol ventrikül global disfonksiyonu gösterdiler (MPİ sırasıyla 0.56±0.12 ve 0.46±0.11, p

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Cite This Article

DURSUNOĞLU, D., KURU, Ö., GÜR, Ş., EVRENGÜL, H., TANRIVERDİ, H., KAFTAN, A., KILIÇ, M. (2022). Metabolik sendromlu kadınlarda gizli sol ventrikül disfonksiyonu mu var?. Anadolu Kardiyoloji Dergisi, Cilt: 5 - Sayı: 4, 283–288. https://ajindex.com/articles/437409

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