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Journals / Anadolu Kardiyoloji Dergisi / 2005 / Cilt: 5 - Sayı: 3

Effects of beta-blockers on transmitral, pulmonary venous flows, and spontaneous echo-contrast grades in heart failure

Kalp yetersizliğinde beta-bloker tedavisinin transmitral ve pulmoner ven akımları ile spontan eko-kontrast düzeyi üzerine etkisi

Aydın DURSUN
Tolga ONUK
Sait Mesut DOĞAN
Hediye MADAK
Fatih ÇAM
Mustafa AYDIN
Metin GÜRSÜRER
Pages
178–181
Publication Date
2022-10-10
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

When the post treatment values were compared with the pretreatment values, it was detected that isovolumetric relaxation time significantly decreased (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: In this study, we aimed to investigate effects of metoprolol treatment on transmitral, pulmonary venous flows and spontaneous echo contrast in patients with heart failure.
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Key Findings & Data:Methods: Twenty-four patients (mean age: 55±8 years) with heart failure were enrolled to the study.
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Conclusion & Impact:When the post treatment values were compared with the pretreatment values, it was detected that isovolumetric relaxation time significantly decreased (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: In this study, we aimed to investigate effects of metoprolol treatment on transmitral, pulmonary venous flows and spontaneous echo contrast in patients with heart failure. Methods: Twenty-four patients (mean age: 55±8 years) with heart failure were enrolled to the study. All were given metoprolol succinate with titrated target dose of 50 mg/d controlled release tablets for 1 month. Transmitral flow and pulmonary venous flow, systolic, diastolic and atrial reversal flow velocities were measured, and compared with the pretreatment values.Results: Heart rate significantly decreased. No significant change was observed in ejection fraction. When the post treatment values were compared with the pretreatment values, it was detected that isovolumetric relaxation time significantly decreased (p

Özet

Amaç: Bu çalışmada sinüs ritmindeki kalp yetersizliği olan hastalarda metoprolol tedavisinin transmitral ve pulmoner ven akımları ile spontan eko-kontrast oluşumu üzerine etkisinin değerlendirilmesi amaçlandı.Yöntemler: Çalışmaya kalp yetersizliği bulunan 24 hasta (yaş ortalaması 55±8 yıl) dahil edildi. Hastalara 1 ay süre ile metoprolol süksinat, kontrollü salınım tableti, 12.5 mg’dan başlanarak hedef doz 50 mg olacak şekilde titre edilerek uygulandı. Tedavi öncesi ve sonrası transtorasik ekokardiyografi uygulandı. Transmitral ve pulmoner venöz akımları ile spontan eko kontrast düzeyi değerlendirildi.Bulgular: Kalp hızı anlamlı oranda azalma gösterdi. Ejeksiyon fraksiyonunda istatistiksel anlamlı değişiklik izlenmedi. Tedavi sonrası öncesi ile karşılaştırıldığında izovolümik gevşeme zamanında belirgin azalma saptandı, (108±27ms’ye karşı 98±22 ms, p

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Cite This Article

DURSUN, A., ONUK, T., DOĞAN, S. M., MADAK, H., ÇAM, F., AYDIN, M., GÜRSÜRER, M. (2022). Effects of beta-blockers on transmitral, pulmonary venous flows, and spontaneous echo-contrast grades in heart failure. Anadolu Kardiyoloji Dergisi, Cilt: 5 - Sayı: 3, 178–181. https://ajindex.com/articles/437399

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References (14)

  1. Xie GY, Berk MR, Smith MD, Gurley JC, De Maria AN. Prognostic value of Doppler transmitral flow patterns in patients with congestive heart failure. J Am Coll Cardiol 1994;24:132-9
  2. Rihal CS, Nishimura RA, Hatle LK, Bailey KR, Tajik AJ. Systolic and diastolic dysfunction in patients with clinical diagnosis of dilated cardiomyopathy: relation to symptoms and prognosis. Circulation 1994;90:2772-9
  3. Pozzoli M, Capomolla S, Sanarico M, et al. Doppler evaluations of left ventricular diastolic filling and pulmonary wedge pressure provide similar prognostic information in patients with systolic dysfunction after myocardial infarction. Am Heart J 1995;129:716-25
  4. Rajagopalan B, Friend JA, Stallard T, Lee GD. Blood flow in pulmonary veins: I. Studies in dog and man. Cardiovasc Res 1979;13:667-76
  5. Klein AL, Tajik AJ. Doppler assessment of pulmonary venous flow in healthy subjects and in patients with heart disease. J Am Soc Echocardiogr 1991;4:379-92
  6. Keren G, Sherez J, Megidish R, Levitt B, Laniado S. Pulmonary venous flow pattern--its relationship to cardiac dynamics. A pulsed Doppler echocardiographic study. Circulation 1985;71:1105-12
  7. Keren G, Meisner JS, Sherez J, Yellin EL, Laniado S. Interrelationship of mid-diastolic mitral valve motion, pulmonary venous flow, and transmitral flow. Circulation 1986;74:36-44
  8. Keren G, Sonnenblick EH, LeJemtel TH. Mitral annulus motion. Relation to pulmonary venous and transmitral flows in normal subjects and in patients with dilated cardiomyopathy. Circulation 1988;78:621-9
  9. Klein AL, Hatle LK, Burstow DJ, et al. Doppler characterization of left ventricular diastolic function in cardiac amyloidosis. J Am Coll Cardiol. 1989;13:1017-26
  10. Bristow M. b-Adrenergic receptor blockade in chronic heart failure. Circulation 2000;101:558–69
  11. Tangeman HJ, Patterson JH. Extended-release metoprolol succinate in chronic heart failure. Ann Pharmacother 2003 May;37:701-10
  12. Herlitz J, Wikstrand J, Denny M, et al. MERIT-HF Study Group. Effects of metoprolol CR/XL on mortality and hospitalizations in patients with heart failure and history of hypertension. J Card Fail. 2002;8:8-14
  13. Sahn DJ, De Maria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation 1978; 58: 1072-83
  14. Schiller NB, Shah PM, Crawford M, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography