Journals / Türk Kardiyoloji Derneği Arşivi / 2013 / Cilt: 41 - Sayı: 8

Effect of overweight on cardiac function in children

Çocuklarda kilo fazlalığının kalp fonksiyonlarına etkisi

Pages
714–723
Publication Date
2022-11-05
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

BMI is associated with a reduction in LV diastolic function in over- weight children.

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: It is known that obesity is related to heart failure.
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Key Findings & Data:Study design: A total of 153 children were enrolled in the study.
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Conclusion & Impact:BMI is associated with a reduction in LV diastolic function in over- weight children.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: It is known that obesity is related to heart failure. Asymptomatic left ventricular diastolic dysfunction (LVDD) is associated with the development of heart failure. The relation- ship between subclinical LVDD and overweight in children is not clear. The purpose of this study was to evaluate the effect of body mass index (BMI) and waist circumference on left ven- tricular mass index (LVMI) and LVDD in overweight children. Study design: A total of 153 children were enrolled in the study. Of these, 91 were normal weight (age-adjusted BMI: 15-85 percentile), and 62 were overweight (age-adjusted BMI: 85-95 percentile). After measuring two-dimensional and M-mode echocardiographic variables, left and right ventricle diastolic functions were assessed by conventional and tissue Doppler imaging. Results: Compared to controls, overweight children had in- creased left atrium, aortic and left ventricular diameters, left ventricular wall thickness, LVM and LVMI, and septal mitral annulus e , septal e /a , lateral e , lateral e /a , lateral tricuspid annulus e , and e /a values. There were negative correlations between tissue Doppler diastolic parameters (septal mitral annulus e , lateral mitral annulus e , lateral tricuspid annulus e , septal mitral annulus e /a , lateral mitral annulus e /a , and lateral tricuspid annulus e /a ) and BMI, waist circumference, insulin, HOMA index, as well as systolic and diastolic blood pressure. Positive correlations were found between LVMI and BMI and between LVMI and waist circumference. BMI was found to be the predictor of decreased mitral anulus septal e , septal e /a , lateral e , lateral e /a . Conclusion: Compared with normal-weight children, over- weight children have decreased LV diastolic function. BMI is associated with a reduction in LV diastolic function in over- weight children.

Özet

Amaç: Obezitenin kalp yetersizliği riski ile ilişkili olduğu bilinmektedir. Semptomsuz sol ventrikül (SV) diyastolik fonksiyon bozukluğu kalp yetersizliği gelişmesi ile ilişkilidir. Çocuklarda kilo fazlalığının subklinik SV diyastolik fonksiyon bozukluğu ile ilişkili olup olmadığı belli değildir. Bu çalışmanın amacı kilolu çocuklarda SV kitle indeksi ve SV diyastolik fonksiyonları üzerine beden kütle indeksi (BKİ) ve bel çevresinin etkisini değerlendirmektir. Çalışma planı: Çalışmaya normal kilolu (yaşa göre ayarlanmış BKİ: %15-85 arası) 91 ve fazla kilolu (yaşa göre ayarlanmış BKİ: %85-95 arası) 61 olmak üzere toplam 153 çocuk katıldı. İki boyutlu, M-Mode görüntüleme ile boyutlar ve çaplar ölçüldü. SV diyastolik fonksiyonu geleneksel ve doku Doppler görüntüleme ile değerlendirildi. Bulgular: Kilolu çocuklarda yüksek yoğunluklu kolesterol düşük, sistolik ve diyastolik kan basıncı (KB), serum insülini, HOMA indeksi, trigliserit (TG), sol atriyum, aort ve SV çapları, SV duvar kalınlıkları, sol ventrikül kitlesi (SVK) ve sol ventrikül kitle indeksi (SVKİ) fazla idi. Mitral anülüs septal e, septal e/a, lateral e, lateral e/a, triküspit lateral anülüs e ve e/a değerleri düşüktü. Mitral anülüs septal e, lateral e, triküspit lateral anülüs e, mitral anülüs septal e/a, lateral e/a ve triküspit lateral anülüs e/a ile BKİ, bel çevresi, serum insülin düzeyi, HOMA indeksi, sistolik ve diyastolik KB arasında negatif korelasyon bulundu. SVKİ ile BKİ ve bel çevresi arasında pozitif korelasyon bulundu. Mitral anülüs septal e, septal e/a, lateral e, lateral e/a için sadece BKİ öngördürücü olarak tespit edildi. Sonuç: Normal kilolu çoçuklara kıyasla kilolu çocuklarda SV diyastolik fonksiyonlarında azalma vardır. Kilolu çocuklarda BKİ, SV diyastolik fonksiyonlarında azalma ile ilişkilidir.

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Cite This Article

DONMA, M. M., AKYÜZ, A., TOPÇU, B., ALPSOY, Ş., NAlBANTOĞLU, B., ÖZDİLEK, B., DEĞİRMENCİ, H., AKKOYUN, D. C. (2022). Effect of overweight on cardiac function in children. Türk Kardiyoloji Derneği Arşivi, Cilt: 41 - Sayı: 8, 714–723. https://ajindex.com/articles/632950

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References (14)

  1. Ogden CL, Carroll MD, Kit BK, Flegal KM. Prevalence of obesity and trends in body mass index among US children and adolescents, 1999-2010. JAMA 2012
  2. CrossRef 2. Barness LA, Opitz JM, Gilbert-Barness E.Obesity: genetic, molecular, and environmental aspects. Am J Med Genet A 2007
  3. CrossRef 3. Daniels SR, Arnett DK, Eckel RH, Gidding SS, Hayman LL, Kumanyika S, et al. Overweight in children and adolescents: pathophysiology, consequences, prevention, and treatment. Circulation 2005
  4. CrossRef 4. Raj M. Obesity and cardiovascular risk in children and adolescents. Indian J Endocrinol Metab 2012
  5. CrossRef 5. Dietz WH. Overweight in childhood and adolescence. N Engl J Med 2004
  6. CrossRef 6. Daniels SR. The consequences of childhood overweight and obesity. Future Child 2006
  7. CrossRef 7. Berenson GS, Srinivasan SR, Bao W, Newman WP 3rd, Tracy RE, Wattigney WA. Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. The Bogalusa Heart Study. N Engl J Med 1998
  8. CrossRef 8. Kenchaiah S, Evans JC, Levy D, Wilson PW, Benjamin EJ, Larson MG, et al. Obesity and the risk of heart failure. N Engl J Med 2002
  9. CrossRef 9. Redfield MM, Jacobsen SJ, Burnett JC Jr, Mahoney DW, Bailey KR, Rodeheffer RJ. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA 2003
  10. Nagueh SF, Middleton KJ, Kopelen HA, Zoghbi WA, Quiñones MA. Doppler tissue imaging: a noninvasive technique for evaluation of left ventricular relaxation and estimation of filling pressures. J Am Coll Cardiol 1997
  11. CrossRef 11. Ommen SR, Nishimura RA, Appleton CP, Miller FA, Oh JK, Redfield MM, et al. Clinical utility of Doppler echocardiography and tissue Doppler imaging in the estimation of left ventricular filling pressures: A comparative simultaneous Doppler-catheterization study. Circulation 2000
  12. Mahfouz RA, Dewedar A, Abdelmoneim A, Hossien EM. Aortic and pulmonary artery stiffness and cardiac function in children at risk for obesity. Echocardiography 2012
  13. CrossRef 13. Zeybek C, Aktuglu-Zeybek C, Onal H, Altay S, Erdem A, Celebi A. Right ventricular subclinical diastolic dysfunction in obese children: the effect of weight reduction with a lowcarbohydrate diet. Pediatr Cardiol 2009
  14. CrossRef 14.Aknc A, Karakurt C, Gurbuz S, Elkran O, Nalba