Journals / Anadolu Kardiyoloji Dergisi / 2006 / Cilt: 6 - Sayı: 2

Tredmil efor testinin oksidan/antioksidan parametreler ve DNA hasarı üzerine etkisi

Effects of treadmill exercise test on oxidative/antioxidative parameters and DNA damage

Pages
135–140
Publication Date
2022-10-10
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Results: Treadmill exercise test leads to the increase of total peroxide (12 ± 3 µmol H2O2/L to 14 ± 3 µmol H2O2/L, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We investigated the acute effects of treadmill exercise test (TET) on total peroxide, total antioxidant capacity (TAC), oxidative stress index (OSI) and DNA damage levels in voluntary and untrained healthy subjects.
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Key Findings & Data:Methods: A total of 113 untrained healthy subjects were included in the study.
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Conclusion & Impact:Results: Treadmill exercise test leads to the increase of total peroxide (12 ± 3 µmol H2O2/L to 14 ± 3 µmol H2O2/L, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We investigated the acute effects of treadmill exercise test (TET) on total peroxide, total antioxidant capacity (TAC), oxidative stress index (OSI) and DNA damage levels in voluntary and untrained healthy subjects. Methods: A total of 113 untrained healthy subjects were included in the study. All subjects maintained a similar diet and physical activity for a week before the test. Blood samples were obtained before and after TET. Total peroxide, TAC, vitamin C and DNA damage were measured. The DNA damage was analyzed by using the Comet assay and OSI was calculated using total peroxide and TAC values. Results: Treadmill exercise test leads to the increase of total peroxide (12 ± 3 µmol H2O2/L to 14 ± 3 µmol H2O2/L, p

Özet

Amaç: Bu çalışmada gönüllü ve antrenmansız sağlıklı kişilerde tredmil efor testinin total peroxid, total antioksidan kapasite (TAK), oksidatif stres indeksi (OSİ) ve DNA hasarı üzerine olan etkisi araştırıldı. Yöntemler: Toplam 113 sağlıklı antrenmansız kişi çalışmaya dahil edildi. Bütün kişiler tredmil testinde bir hafta öncesinde benzer diyet ve fiziki aktivite önerildi. Efor testine önce ve hemen sonra kan örnekleri alındı. Total peroxid, TAK, vitamin C ve DNA hasarı ölçümleri yapıldı. DNA hasarı Comet değerlendirme yöntemi ile OSİ'de total peroxidin TAK'a bölünmesi ile hesaplandı. Bulgular: Tredmil testi sonucunda öncesine göre total peroxid (12 ± 3 µmol H2O2/L'den 14 ± 3 µmol H2O22/L’ye, p

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Cite This Article

DEMİRBAĞ, R., KOÇYİĞİT, A., ÇELİK, H., GÜZEL, S., YILMAZ, R., ÖZCAN, E. (2022). Tredmil efor testinin oksidan/antioksidan parametreler ve DNA hasarı üzerine etkisi. Anadolu Kardiyoloji Dergisi, Cilt: 6 - Sayı: 2, 135–140. https://ajindex.com/articles/437306

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