Journals / Anadolu Kardiyoloji Dergisi / 2008 / Cilt: 8 - Sayı: 3

Koşu bandı egzersiz Bruce protokolü ve stres miyokard perfüzyon görüntüleme ile submaksimal hedef kalp hızı ve miyokardiyal iskeminin saptanması

Submaximal target heart rate and the detection of myocardial ischemia by stress myocardial perfusion imaging using the treadmill exercise Bruce protocol

Pages
192–196
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In these settings, in patients who fail to attain the THR, it would be possible to proceed to the stress MPI test.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: It has been postulated that if patients fail to achieve their age-predicted target heart rate (THR: 85% of predicted maximal HR), the electrocardiographic changes following exercise treadmill test (ETT) and also scintigraphic results of this stress protocol for myocardial perfusion imaging (MPI) are unreliable.
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Key Findings & Data:We decided to assess the ability of submaximal ETT in provoking ischemia as determined by MPI.Methods: One hundred and nine patients (60 female, 49 male, mean age: 50.8±11.4, range: 32-76 years), were prospectively assessed with MPI after stress protocol of ETT.
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Conclusion & Impact:In these settings, in patients who fail to attain the THR, it would be possible to proceed to the stress MPI test.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: It has been postulated that if patients fail to achieve their age-predicted target heart rate (THR: 85% of predicted maximal HR), the electrocardiographic changes following exercise treadmill test (ETT) and also scintigraphic results of this stress protocol for myocardial perfusion imaging (MPI) are unreliable. We decided to assess the ability of submaximal ETT in provoking ischemia as determined by MPI.Methods: One hundred and nine patients (60 female, 49 male, mean age: 50.8±11.4, range: 32-76 years), were prospectively assessed with MPI after stress protocol of ETT. Forty-nine patients failed to attain THR. Myocardial perfusion imaging was performed based on the 1-day protocol, using Technetium-99m sestamibi (99mTc-MIBI).Results: Sixty patients attained THR, of which 28 patients (46.7%) had normal myocardial perfusion pattern and 32 patients (53.3%) had scintigraphic evidence of ischemia. The remaining 49 patients had submaximal ETT, of which 15 patients (30.6%) had normal results and 34 patients (69.4%) had scintigraphic evidence of ischemia. Although ischemia was more common in those patients with submaximal ETT, however the difference was not statistically significant (p=0.088).Conclusion: Ischemia is more common in patients who had performed a sub-maximal ETT. It could be a logical hypothesis that ischemic heart disease may limit the ability of patients to complete ETT and therefore, it would not be judged that submaximal ETT is always insufficient for MPI. In these settings, in patients who fail to attain the THR, it would be possible to proceed to the stress MPI test.

Özet

Amaç: Egzersiz stres test sırasında hastalar, yaşa bağlı tahmin edilen hedef kalp hızına (THR: 85% maksimum tahmin edilen kalp hızı) ulaşamazlar ise, egzersiz koşu bandı testi (ETT) sırasındaki elektrokardiyografik değişiklikleri ile miyokard perfüzyon görüntüleme (MPI) stres protokolü sintigrafik sonuçlarının güvenilmez olduğu kabul edilmektedir. Biz, MPI tarafından belirlenmiş olan, iskemiyi provoke etmekte olan alt-azami ETT'nin yeteneğini değerlendirmeyi kararlaştırdık.Yöntemler: Toplam 190 hasta (60 kadın 49 erkek, ortalama yaş: 50.8 ±-11.4 yıl, oran: 32-76 yaş), ETT'nin stres protokolünden sonra MPI ile ileriye dönük olarak değerlendirildi. Kırk dokuz hasta THR hedefine ulaşmakta başarısız oldu. Miyokard perfüzyon görüntüleme çalışması, 1 - gün protokolüne göre, Technetium-99m sestamibi (99mTc-MIBI) protokolü kullanılarak yapıldı. Bulgular: Kalp hızı hedefine ulaşan 60 hastanın, 28’nde (46.7%) normal miyokard perfüzyon saptandı ve 32 hastada (53.3%) sintigrafide iskemi kanıtı vardı. Kalan 49 hasta submaksimal ETT ye ulaştı, bunların 15’nde (30.6%) normal perfüzyon mevcuttu ve 34 hastada (69.4%), iskemi kanıtı vardı. Submaksimal ETT ile birlikte bu hastalarda daha sık iskemi olmasına rağmen, yine de fark, istatistiksel yönden önemli değildi (p=0.088). Sonuç: İskemi submaksimal ETT’li olan hastalarda daha yaygındır. İskemik kalp hastalığının, ETT'i tamamlaması için hastaların yeteneğini sınırlayabildiği mantıklı bir hipotez olabilir ve bu yüzden, submaksimal ETT’in, her zaman MPI için yetersiz olduğu kararı doğru değildi. Bu şartlarda, THR hedefine ulaşmakta başarısız olan hastalarda, stres MPI testi yapmak mümkün olabilir.

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Cite This Article

GHOLAMREZANEZHAD, A., MIRPOUR, S., HAJIMOHAMMADI, H., POURMOSLEMI, A. (2022). Koşu bandı egzersiz Bruce protokolü ve stres miyokard perfüzyon görüntüleme ile submaksimal hedef kalp hızı ve miyokardiyal iskeminin saptanması. Anadolu Kardiyoloji Dergisi, Cilt: 8 - Sayı: 3, 192–196. https://ajindex.com/articles/436976

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