Journals / Anadolu Kardiyoloji Dergisi / 2009 / Cilt: 9 - Sayı: 6

Furosemid infüzyonu kalp cerrahisi sonrası renal replasman tedavi ihtiyacını önlemektedir

Furosemide infusion prevents the requirement of renal replacement therapy after cardiac surgery

Pages
499–504
Publication Date
2022-10-10
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Methods: Between August 1, 2007 and July 31, 2008, 100 adult patients undergoing elective coronary artery bypass surgery (CABG) surgery with normal renal function (creatinine

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Acute kidney injury (AKI) is a devastating complication following cardiac surgery and the ideal management is controversial.
📊
Key Findings & Data:This prospective, randomized, open-label and double-blinded study analyzed the renoprotective effects of furosemide infusion and intermittent bolus therapy administered with dopamine infusion in cardiac surgical patients.
💡
Conclusion & Impact:Methods: Between August 1, 2007 and July 31, 2008, 100 adult patients undergoing elective coronary artery bypass surgery (CABG) surgery with normal renal function (creatinine
🔬Design:Research Article
📍Scope:2007 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: Acute kidney injury (AKI) is a devastating complication following cardiac surgery and the ideal management is controversial. This prospective, randomized, open-label and double-blinded study analyzed the renoprotective effects of furosemide infusion and intermittent bolus therapy administered with dopamine infusion in cardiac surgical patients. Methods: Between August 1, 2007 and July 31, 2008, 100 adult patients undergoing elective coronary artery bypass surgery (CABG) surgery with normal renal function (creatinine

Özet

Amaç: Akut böbrek yetmezliği (ABY) kalp cerrahisi sonrası gelişen önemli bir komplikasyondur ve tedavisi tartışmalıdır. Bu prospektif, randomize, açık, çift kör çalışmanın amacı dopamin infüzyonu eşliğinde sürekli veya bolus furosemid uygulamasının renal koruyucu etkilerini analiz etmektir. Yöntemler: Çalışmaya 1 Ağustos 2007 ve 31 Temmuz 2008 tarihleri arasında izole koroner arter baypas cerrahisi uygulanan 100 erişkin hasta dahil edildi. Hastalar bolus (Grup 1, n=50,1-3mg/kg) veya infüzyon (Grup 2, n=50,10mg/ml) furosemidin renal koruyuculuğu karşılaştırılmak üzere randomize edildi. Devamlı değişkenler ortalama ± SS olarak belirtildi ve Student’s t testi veya ANOVA (tekrarlı ölçümler varyans analizi) testleri kullanıldı. Önemlilik p

🔖

Cite This Article

ARSAN, S., BİTİR, N., KUNT, T. A., ATALAN, N., AKGÜN, S. (2022). Furosemid infüzyonu kalp cerrahisi sonrası renal replasman tedavi ihtiyacını önlemektedir. Anadolu Kardiyoloji Dergisi, Cilt: 9 - Sayı: 6, 499–504. https://ajindex.com/articles/436944

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (13)

  1. Conlon PJ, Stafford-Smith M, White WD, Newman MF, King S, Winn MP, et al. Acute renal failure following cardiac surgery. Nephrol Dial Transplant 1999; 14: 1158-62
  2. Rosner MH, Okusa MD. Acute kidney injury associated with cardiac surgery. Clin J Am Soc Nephrol 2006; 1: 19-32
  3. Andersson LG, Ekroth R, Bratteby LE, Hallhagen S, Wesslén O. Acute renal failure after coronary surgery-a study of incidence and risk factors in 2009 consecutive patients. Thorac Cardiovasc Surg 1993; 41: 237-41
  4. Sirivella S, Gielchinsky I, Parsonnet V. Mannitol, furosemide, and dopamine infusion in postoperative renal failure complicating cardiac surgery. Ann Thorac Surg 2000; 69: 501-6
  5. Doddakula K, Al-Sarraf N, Gately K, Hughes A, Tolan M, Young V, et al. Predictors of acute renal failure requiring renal replacement therapy post cardiac surgery in patients with preoperatively normal renal function. Interact Cardiovasc and Thorac Surg 2007; 6: 314-8
  6. Weerasinghe A, Hornick P, Smith P, Taylor K, Ratnatunga C. Coronary artery bypass grafting in non-dialysis-dependent mild-to-moderate renal dysfunction. J Thorac Cardiovasc Surg 2001; 121: 1083-9
  7. Chertow GM, Lazarus JM, Christiansen CL, Cook EF, Hammermeister KE, Grover F, et al. Preoperative renal risk stratification. Circulation 1997; 95: 878-84
  8. Suen WS, Mok CK, Chiu SW, Cheung KL, Lee WT, Cheung D, et al. Risk factors for development of acute renal failure (ARF) requiring dialysis in patients undergoing cardiac surgery. Angiology 1998; 49: 789-800
  9. Hall RI, Smith MS, Rocker G. The systemic inflammatory response to cardiopulmonary bypass: pathophysiological, therapeutic, and pharmacological considerations. Anesth Analg 1997; 85: 766-82
  10. Isbir SC, Tekeli A, Ergen A, Yılmaz H, Ak K, Civelek A, et al. Genetic polymorphisms contribute to acute kidney injury after coronary artery bypass grafting. Heart Surg Forum 2007; 10: E439-44
  11. Lassnigg A, Donner E, Grubhofer G, Presterl E, Druml W, Hiesmayr M. Lack of renoprotective effects of dopamine and furosemide during cardiac surgery. J Am Soc Nephrol 2000; 11: 97-104
  12. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute Dialysis Quality Initiative workgroup. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004; 8: R204-12
  13. Bojar RM. Manual of perioperative care in cardia