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Journals / Anadolu Kardiyoloji Dergisi / 2010 / Cilt: 10 - Sayı: 5

D-dimer testi akut aort disseksiyonlarını belirlemede acil servis hekimlerine yardımcı olabilir mi?

Can D-dimer testing help emergency department physicians to detect acute aortic dissections?

Selen BAYRAKTAROĞLU
Tanzer ÇALKAVUR
Selahattin KIYAN
Murat ÖZSARAÇ
Aslıhan YÜRÜKTÜMEN
Ersin AKSAY
Murat ERSEL
Pages
434–439
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In comparison of the two groups, positive D-dimer results were found to be significantly higher in acute aortic dissection group than in non-acute aortic dissection group (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: To determine the diagnostic accuracy of D-dimer testing for detection of acute aortic dissection.
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Key Findings & Data:The study was conducted in a tertiary care center between February 2006-August 2008.
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Conclusion & Impact:In comparison of the two groups, positive D-dimer results were found to be significantly higher in acute aortic dissection group than in non-acute aortic dissection group (p
🔬Design:Review & Systematic Survey
📍Scope:2006 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: To determine the diagnostic accuracy of D-dimer testing for detection of acute aortic dissection. Methods: This study is a retrospective chart review of patients who had been evaluated with suspicion of acute aortic dissection. All patients’ D-dimer levels were determined prior to their further work up in the emergency department. The study was conducted in a tertiary care center between February 2006-August 2008. The D-dimer assay used was the immunoturbidimetric assay, with a normal range up to 0.246 µg/ml. Statistical analysis was accomplished using Chi-square test, Student’s t-test and a receiver-operating characteristics (ROC) curve analysis.Results: Ninety-nine patients were included in the study, 30 patients were diagnosed as having acute aortic dissection and 69 patients were evaluated in non-acute aortic dissection group. In comparison of the two groups, positive D-dimer results were found to be significantly higher in acute aortic dissection group than in non-acute aortic dissection group (p

Özet

Amaç: D-dimer testinin akut aort disseksiyonunu belirlemede tanısal değerini saptamak. Yöntemler: Bu çalışma retrospektif bir çalışmadır. Acil serviste akut aort disseksiyonu şüphesi mevcut olan ve ileri tetkik öncesi D-dimer testi istenen hastalar çalışmaya dâhil edilmiştir. 3. basamak bir sağlık kuruluşunda gerçekleştirilen çalışmada, Şubat 2006-Ağustos 2008 tarihleri arasındaki kayıtlar incelenmiştir. Kullanılan D-dimer ölçüm yöntemi immunoturbidimetrik yöntemdir ve 0.246 µg/ml'ye kadar olan sonuçlar normal olarak kabul edilmiştir. İstatistiksel analizde Ki-kare testi, Student’s t-testi kullanılmış, ayrıca ROC eğrisi analizi yapılmıştır. Bulgular: Çalışmaya 30 akut aort disseksiyonu mevcut, 69 akut aort disseksiyonu mevcut olmayan kontrol grubu olmak üzere 99 hasta dâhil edilmiştir. Bu iki gruba ait D-dimer ölçümlerinin karşılaştırılmasında akut aort disseksiyonu olan hastaların olmayanlara göre istatistiksel anlamlı olarak daha fazla pozitif sonucunun olduğu görülmüştür (p

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Cite This Article

BAYRAKTAROĞLU, S., ÇALKAVUR, T., KIYAN, S., ÖZSARAÇ, M., YÜRÜKTÜMEN, A., AKSAY, E., ERSEL, M. (2022). D-dimer testi akut aort disseksiyonlarını belirlemede acil servis hekimlerine yardımcı olabilir mi?. Anadolu Kardiyoloji Dergisi, Cilt: 10 - Sayı: 5, 434–439. https://ajindex.com/articles/436705

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References (13)

  1. Mehta RH, Suzuki T, Hagan PG, Bossone E, Gilon D, Llovet A, et al. Predicting death in patients with acute type a aortic dissection. Circulation 2002; 105: 200-6
  2. Hagan PG, Nienaber CA, Isselbacher EM, Bruckman D, Karavite DJ, Russman PL, et al. The International Registry of Acute Aortic Dissection (IRAD): New insights into an old disease. JAMA 2000; 283: 897-903
  3. Sarasin FP, Louis-Simonet M, Gaspoz JM, Junod AF. Detecting acute thoracic aortic dissection in the emergency department: time constraints and choice of the optimal diagnostic test. Ann Emerg Med 1996; 28: 278-88
  4. Sie P. The value of laboratory tests in the diagnosis of venous thromboembolism. Haematologica 1995; 80: 57-60
  5. The DVTENOX Study Group. Markers of haemostatic system activation in acute deep venous thrombosis evolution during the first days of heparin treatment. Thromb Haemost 1993; 70: 909-14
  6. Weber T, Högler S, Auer J, Berent R, Lassnig E, Kvas E, et al. D-dimer in acute aortic dissection. Chest 2003; 123: 1375-8
  7. Eggebrecht H, Naber CK, Bruch C, Kröger K, Von Birgelen C, Schmermund A, et al. Value of plasma fibrin D-dimers for detection of acute aortic dissection. J Am Coll Cardiol 2004; 44: 804-9
  8. Perez A, Abbet P, Drescher MJ. D-dimers in the emergency department evaluation of aortic dissection. Acad Emerg Med 2004; 11: 397-400
  9. Hazui H, Fukumoto H, Negoro N, Hoshiga M, Muraoka H, Nishimoto M, et al. Simple and useful tests for discriminating between acute aortic dissection of the ascending aorta and acute myocardial infarction in the emergency setting. Circ J 2005; 69: 677-82
  10. Akutsu K, Sato N, Yamamoto T, Morita N, Takagi H, Fujita N, et al. A rapid bedside D-dimer assay (Cardiac D-dimer) for screening of clinically suspected acute aortic dissection. Circ J 2005; 69: 397-403
  11. Ohlmann P, Faure A, Morel O, Petit H, Kabbaj H, Meyer N, et al. Diagnostic and prognostic value of circulating D-Dimers in patients with acute aortic dissection. Crit Care Med 2006; 34: 1358-64
  12. Weber T, Rammer M, Auer J, Maurer E, Aspoeck G, Eber B. Plasma concentrations of D-dimer predict mortality in acute type A aortic dissection. Heart 2006; 92: 836-7
  13. Hazui H, Nishimoto M, Hoshiga M, Negoro N, Muraoka H, Murai M, et al. Young adult patients with short dissection length and thrombosed false lumen without ulcer-like projections are liable to have false-negative results of D-dimer testing for acute aortic dissection based on a study of 113 cases. Circ J 2006; 70: