Journals / Anadolu Kardiyoloji Dergisi / 2012 / Cilt: 12 - Sayı: 8

Hemodinamik olarak stabil pulmoner embolili hastalarda sağ ventrikül Tei indeksi ve troponin-T arasındaki ilişki

Relationship between cardiac troponin-T and right ventricular Tei index in patients with hemodynamically stable pulmonary embolism: an observational study

Pages
659–665
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Significant correlations were observed between RV Tei index and sPAP with cTn-T levels (r=0.467 and r=0.468, p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The role of increased troponin level in risk stratification of acute pulmonary embolism (PE) is well documented.
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Key Findings & Data:However, relation between right ventricular (RV) myocardial performance (Tei) index and cardiac troponin-T (cTn-T) has not been well investigated.
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Conclusion & Impact:Significant correlations were observed between RV Tei index and sPAP with cTn-T levels (r=0.467 and r=0.468, p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: The role of increased troponin level in risk stratification of acute pulmonary embolism (PE) is well documented. However, relation between right ventricular (RV) myocardial performance (Tei) index and cardiac troponin-T (cTn-T) has not been well investigated. The purpose of this observational prospective study was to assess the relationship between the RV Tei index and cTn-T in patients with acute normotensive PE. Methods: Thirty-eight patients with acute PE diagnosed by computed spiral tomography pulmonary angiography were enrolled to this prospective observational study. All study population underwent a comprehensive echocardiographic study including tissue Doppler imaging within first 12 hours of admission. cTn-T levels were measured on admission. Follow-up echocardiography was performed routinely at the 7th day of hospitalization. Echocardiographic evaluation was repeated at 90 days in patients with insufficient improvement of RV Tei index. The difference between the baseline and follow-up data was analyzed using the paired sample t-test or Wilcoxon test according to normality of distribution. Results: The mean of the RV Tei index was 0.46±0.14 and the mean systolic pulmonary artery pressure (sPAP) was 40±20 mmHg. Increased cTn-T level was detected in 37% of the patients (normal value 0.01< ng/mL). Significant correlations were observed between RV Tei index and sPAP with cTn-T levels (r=0.467 and r=0.468, p

Özet

Amaç: Akut pulmoner embolide (PE) risk tayinde kardiyak troponin-T (cTrop-T)nin rolü iyi dokümante edilmiştir. Bununla birlikte, sağ ventrikül (SV) miyokardiyal performans (Tei) indeksi ve cTn-T arasındaki ilişki çok iyi araştırılmamıştır. Bu çalışmanın amacı, normotansif akut PE hastalarında SV Tei indeksi ile cTn-T arasındaki ilişkiyi değerlendirmektir. Yöntemler: Prospektif gözlemsel bu çalışmaya, bilgisayarlı spiral tomografik pulmoner anjiyografi ile tanısı konulan 38 PE hastası dahil edildi. Tüm çalışma popülâsyonuna, hastaneye kabulün ilk 12 saati içinde, doku Doppler görüntülemeyi içeren kapsamlı bir ekokardiyografik inceleme yapıldı. cTn-T seviyesi hastaneye kabulde ölçüldü. Hastanedeki tedavinin yedinci gününde rutin olarak takip ekokardiyografisi yapıldı. SV Tei indeksinde düzelme olmayan hastaların ekokardiyografisi doksanıncı günde tekrarlandı. Başlangıç ve takip değerleri dağılıma uygun olarak bağımsız örneklem t-testi veya Wilcoxon test ile değerlendirildi. Bulgular: Ortalama SV Tei indeksi 0.46±0.14 ve ortalama sistolik pulmoner arter basıncı (sPAP) 40±20 mmHg idi. Hastaların %37sinde artmış cTn-T düzeyi saptandı (normal değer 0.01< ng/mL). SV Tei indeksi, sPAP ve cTn-T düzeyi arasında anlamlı korelasyon gözlendi (r=0.467 ve r=0.468, p

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Cite This Article

KARAMAN, K., KUTLU, M., KIRIŞ, A., BÜLBÜL, Y., ÖZTUNA, F., ÖZLÜ, T., ÖZSU, S. (2022). Hemodinamik olarak stabil pulmoner embolili hastalarda sağ ventrikül Tei indeksi ve troponin-T arasındaki ilişki. Anadolu Kardiyoloji Dergisi, Cilt: 12 - Sayı: 8, 659–665. https://ajindex.com/articles/436453

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