Journals / Türk Kardiyoloji Derneği Arşivi / 2014 / Cilt: 42 - Sayı: 1

Romatoit artritli hastalarda Tp-e süresi ve Tp-e/QT oranının değerlendirilmesi

Evaluation of Tp-e interval and Tp-e/QT ratio in patients with rheumatoid arthritis

Pages
29–34
Publication Date
2022-11-05
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Results: Tp-e interval and Tp-e/QT ratio were increased in RA patients compared to the controls (72.6±8.2 vs 66.4±8.5 ms, 0.20±0.02 vs 0.18±0.02; p

📌 3 Key Takeaways

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Objective & Hypothesis:Objectives: Several studies have suggested that the interval rom the peak to the end of the electrocardiographic T wave Tp-e) may correspond to the transmural dispersion of repolar- zation and that increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias.
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Key Findings & Data:Study design: Ninety-six patients (72 females, 24 males; mean age 43.8±11.8 years) with RA and 50 controls (35 females, 15 males; mean age 44.2±11.1 years) were included.
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Conclusion & Impact:Results: Tp-e interval and Tp-e/QT ratio were increased in RA patients compared to the controls (72.6±8.2 vs 66.4±8.5 ms, 0.20±0.02 vs 0.18±0.02; p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objectives: Several studies have suggested that the interval rom the peak to the end of the electrocardiographic T wave Tp-e) may correspond to the transmural dispersion of repolar- zation and that increased Tp-e interval and Tp-e/QT ratio are associated with malignant ventricular arrhythmias. The aim of his study was to evaluate ventricular repolarization by using he Tp-e interval and Tp-e/QT ratio in patients with rheumatoid arthritis (RA), and to assess the relation with inflammation. Study design: Ninety-six patients (72 females, 24 males; mean age 43.8±11.8 years) with RA and 50 controls (35 females, 15 males; mean age 44.2±11.1 years) were included. From the 12- ead electrocardiogram, Tp-e interval and Tp-e/QT ratio were measured. Blood samples were taken for erythrocyte sedi- mentation rate (ESR) and plasma levels of C-reactive protein CRP). These parameters were compared between groups. The relationship between ventricular repolarization and inflam- mation was assessed by Pearson correlation coefficients. Results: Tp-e interval and Tp-e/QT ratio were increased in RA patients compared to the controls (72.6±8.2 vs 66.4±8.5 ms, 0.20±0.02 vs 0.18±0.02; p

Özet

Amaç: Elektrokardiyogramda T dalgasının tepesinden sonuna kadar olan aralığın (Tp-e) repolarizasyon dispersiyonuna karşılık gelebileceği ve Tp-e aralığı ve Tp-e/QT oranındaki artışın hayatı tehdit eden ventrikül aritmileri ile ilişkili olduğu çeşitli çalışmalarda gösterilmiştir. Bu çalışmanın amacı romatoit artrit (RA) saptanan hastalarda Tp-e aralığı ve Tp-e/QT oranını kullanarak ventrikül repolarizayonunu değerlendirmek ve enflamasyon ile ilişkisini araştırmaktır. Çalışma planı: Romatoit artritli 96 hasta (72 kadın, 24 erkek; ort. yaş 43.8±11.8 yıl) ve kontrol grubu için 50 kişi (35 kadın, 15 erkek; ort. yaş. 44.2±11.1 yıl) çalışmaya alındı. On iki derivasyonlu elektrokardiyogramdan Tp-e süresi ve Tp-e/QT oranı ölçüldü. Eritrosit sedimentasyon hızı (ESH) ve C-reaktif protein (CRP) düzeyleri için kan örneği alındı. Bu parametreler gruplar arasında karşılaştırıldı. Ventrikül repolarizasyonu ve enflamasyon arasındaki ilişki Pearson korelasyon analizi ile değerlendirildi. Bulgular: Kontrol grubu ile karşılaştırıldığında, Tp-e aralığı ve Tp-e/QT oranı RAlı hastalarda daha yüksek idi (sırasıyla, 72.6±8.2 ve 66.4±8.5 ms, p

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Cite This Article

KARAMAN, K., ZENCİR, C., ÇETİN, M., ÇETİN, G. Y., NACAR, A. B., AKKOYUN, M., ACAR, G., DİMAK, İ., YILDIRIM, M. N., SAYARLIOĞLU, M. (2022). Romatoit artritli hastalarda Tp-e süresi ve Tp-e/QT oranının değerlendirilmesi. Türk Kardiyoloji Derneği Arşivi, Cilt: 42 - Sayı: 1, 29–34. https://ajindex.com/articles/632815

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References (14)

  1. Voskuyl AE. The heart and cardiovascular manifestations in rheumatoid arthritis. Rheumatology (Oxford) 2006
  2. 45 Suppl 4:iv4-7. CrossRef 2. Charles-Schoeman C. Cardiovascular disease and rheumatoid arthritis: an update. Curr Rheumatol Rep 2012
  3. Seferović PM, Ristić AD, Maksimović R, Simeunović DS, Ristić GG, Radovanović G, et al. Cardiac arrhythmias and conduction disturbances in autoimmune rheumatic diseases. Rheumatology (Oxford) 2006
  4. 45 Suppl 4:iv39-42. CrossRef 4. Evrengül H, Dursunoglu D, Cobankara V, Polat B, Seleci D, Kabukçu S, et al. Heart rate variability in patients with rheumatoid arthritis. Rheumatol Int 2004
  5. CrossRef 5. Janse van Rensburg DC, Ker JA, Grant CC, Fletcher L. Autonomic impairment in rheumatoid arthritis. Int J Rheum Dis 2012
  6. CrossRef 6. Mountantonakis S, Deo R. Biomarkers in atrial fibrillation, ventricular arrhythmias, and sudden cardiac death. Cardiovasc Ther 2012
  7. CrossRef 7. Antzelevitch C, Shimizu W, Yan GX, Sicouri S. Cellular basis for QT dispersion. J Electrocardiol 1998
  8. 30 Suppl:168-75. 8. Kors JA, Ritsema van Eck HJ, van Herpen G. The meaning of the Tp-Te interval and its diagnostic value. J Electrocardiol 2008
  9. CrossRef 9. Antzelevitch C, Sicouri S, Di Diego JM, Burashnikov A, Viskin S, Shimizu W, et al. Does Tpeak-Tend provide an index of transmural dispersion of repolarization? Heart Rhythm 2007
  10. CrossRef 10. Castro Hevia J, Antzelevitch C, Tornés Bárzaga F, Dorantes Sánchez M, Dorticós Balea F, Zayas Molina R, et al. Tpeak- Tend and Tpeak-Tend dispersion as risk factors for ventricular tachycardia/ventricular fibrillation in patients with the Brugada syndrome. J Am Coll Cardiol 2006
  11. CrossRef 11. Smetana P, Schmidt A, Zabel M, Hnatkova K, Franz M, Huber K, et al. Assessment of repolarization heterogeneity for prediction of mortality in cardiovascular disease: peak to the end of the T wave interval and nondipolar repolarization components. J Electrocardiol 2011
  12. CrossRef 12. Erikssen G, Liestøl K, Gullestad L, Haugaa KH, Bendz B, Amlie JP. The terminal part of the QT interval (T peak to T end): a predictor of mortality after acute myocardial infarction. Ann Noninvasive Electrocardiol 2012
  13. CrossRef 13. Watanabe N, Kobayashi Y, Tanno K, Miyoshi F, Asano T, Kawamura M, et al. Transmural dispersion of repolariza tion and ventricular tachyarrhythmias. J Electrocardiol 2004
  14. CrossRef 14. Gupta P, Patel C, Patel H, Nara