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Journals / Anadolu Kardiyoloji Dergisi / 2013 / Cilt: 13 - Sayı: 4

Hafif orta derecede romatizmal mitral kapak darlığı ve normal sol ventrikül ejeksiyon fraksiyonu olan hastalarda subklinik sol ventrikül sistolik disfonksiyonu: Bir gözlemsel çalışma

Subclinical left ventricular systolic dysfunction in patients with mild-to-moderate rheumatic mitral stenosis and normal left ventricular ejection fraction: An observational study

Özlem YILDIRIMTÜRK
Selen YURDAKUL
Fatma Funda HELVACIOĞLU
Saide AYTEKİN
Yelda TAYYARECİ
Pages
328–336
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Both longitudinal and circumferential S and SRs were significantly reduced in patients with MS (p

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Mitral valve stenosis (MS) remains as an important cause of morbidity despite evolution in diagnosis and treatment.
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Key Findings & Data:The purpose of this study was to evaluate subclinical LV systolic dysfunction in a cohort of isolated mild-to-moderate MS patients with normal LV ejection fraction (EF) by using tissue Doppler imaging (TDI) and velocity vector imaging (VVI) techniques.
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Conclusion & Impact:Both longitudinal and circumferential S and SRs were significantly reduced in patients with MS (p
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Mitral valve stenosis (MS) remains as an important cause of morbidity despite evolution in diagnosis and treatment. Generally, left ventricular (LV) systolic functions are well preserved in patients with MS. However, there are some studies showing impaired LV systolic functions in patients with pure MS. The purpose of this study was to evaluate subclinical LV systolic dysfunction in a cohort of isolated mild-to-moderate MS patients with normal LV ejection fraction (EF) by using tissue Doppler imaging (TDI) and velocity vector imaging (VVI) techniques. Methods: Fifty patients with isolated mild-to-moderate MS (84% female, mean age 49.1±10.0 years) and 60 healthy subjects (76.7% female, mean age 49.1±10.5) were included in this cross-sectional observational study. Conventional echocardiography, TDI, strain (S) and strain rate (SRs) analysis were performed in all patients. Results: Transmitral mean pressure gradient was 6.4±3.0 mmHg and mean mitral valve area was 1.45±0.36 cm2 in patients with MS. Both longitudinal and circumferential S and SRs were significantly reduced in patients with MS (p

Özet

Amaç: Tanı ve tedavideki gelişmelere rağmen mitral kapak darlığı (MD) genç erişkinlerde morbiditenin önemli bir sebebidir. Genellikle, MD olan hastalarda sol ventrikül (SV) fonksiyonları iyi korunmuştur. Ancak bazı çalışmalarda saf MD olan hastalarda SV sistolik fonksiyonlarının bozulduğu gösterilmiştir. Bu çalışmanın amacı; izole hafif-orta MD olan, normal SV ejeksiyon fraksiyonlu hasta kohortunda doku Doppler görüntüleme (DDG) ve hız vektör görüntüleme (HVG) yöntemlerini kullanarak, bu hastalarda subklinik sol ventrikül sistolik disfonksiyon varlığını araştırmaktır. Yöntemler: İzole hafif-orta MD olan 50 hasta (%84 kadın, ortalama yaş 49.1±10.0 yıl) ve 60 sağlıklı kişi (%76.7 kadın, ortalama yaş 49.1±10.5 yıl) göz- lemsel kesitsel çalışmaya dahil edildi. Tüm hastalara konvansiyonel ekokardiyografi, DDG ve HVG ile strain (S) ve strain oranı (SR) analizi yapıldı. Bulgular: MD olan hastalarda ortalama transmitral gradient 6.4±3.0 mmHg ve ortalama mitral kapak alanı 1.45±0.36 cm2 olarak bulundu. MD olan hastalarda hem longitüdinal hem de sirkümferensiyal S ve SR değerleri belirgin olarak düşük bulundu (p

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Cite This Article

YILDIRIMTÜRK, Ö., YURDAKUL, S., HELVACIOĞLU, F. F., AYTEKİN, S., TAYYARECİ, Y. (2022). Hafif orta derecede romatizmal mitral kapak darlığı ve normal sol ventrikül ejeksiyon fraksiyonu olan hastalarda subklinik sol ventrikül sistolik disfonksiyonu: Bir gözlemsel çalışma. Anadolu Kardiyoloji Dergisi, Cilt: 13 - Sayı: 4, 328–336. https://ajindex.com/articles/436289

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