Journals / Anadolu Kardiyoloji Dergisi / 2014 / Cilt: 14 - Sayı: 8

Association between admission mean platelet volume and ST segment resolution after thrombolytic therapy for acute myocardial infarction

Pages
728–734
Publication Date
2022-10-10
DOI
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⚡ TL;DR(Too Long; Didn't Read)

Patients were grouped into two as with

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Mean platelet volume (MPV), one of the indices of platelet reactivity has been shown to be related to impaired angiographic reperfusion in ST-segment elevation myocardial infarction (STEMI) patients treated with primary angioplasty or thrombolytics.
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Key Findings & Data:In this study, we aimed to investigate whether MPV on admission is associated with ST-segment resolution in STEMI patients treated with thrombolytics.Methods: We retrospectively evaluated 232 consecutive patients with a diagnosis of first STEMI who were administered thrombolytic therapy within 12 hours of onset of chest pain.
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Conclusion & Impact:Patients were grouped into two as with
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: Mean platelet volume (MPV), one of the indices of platelet reactivity has been shown to be related to impaired angiographic reperfusion in ST-segment elevation myocardial infarction (STEMI) patients treated with primary angioplasty or thrombolytics. However data regarding MPV and its association with ST-segment resolution; an indicator of epicardial and tissue level reperfusion in the setting of STEMI are limited. In this study, we aimed to investigate whether MPV on admission is associated with ST-segment resolution in STEMI patients treated with thrombolytics.Methods: We retrospectively evaluated 232 consecutive patients with a diagnosis of first STEMI who were administered thrombolytic therapy within 12 hours of onset of chest pain. ST segment resolution based on baseline and 90 minute electrocardiographies were measured. Patients were grouped into two as with

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Cite This Article

KIRBAŞ, Ö., KURMUŞ, Ö., KÖSEOĞLU, C., KARADUMAN, B. D., YAŞAR, A. S., ALEMDAR, R., ALİ, S., BİLGE, M. (2022). Association between admission mean platelet volume and ST segment resolution after thrombolytic therapy for acute myocardial infarction. Anadolu Kardiyoloji Dergisi, Cilt: 14 - Sayı: 8, 728–734. https://ajindex.com/articles/436033

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References (1)

  1. Davi G, Patrono C. Platelet activation and atherothrombosis. N Engl J Med 2007; 357: 2482-94. [CrossRef] 2. Meadows TA, Bhatt DL. Clinical aspects of platelet inhibitors and thrombus formation. Circ Res 2007; 100: 1261-75. [CrossRef] 3. Van der Loo B, Martin JF. A role for changes in platelet production in the cause of acute coronary syndromes. Arterioscler Thromb Vasc Biol 1999; 19: 672-9. [CrossRef] 4. Chu SG, Becker RC, Berger PB, Bhatt DL, Eikelboom JW, Konkle B, et al. Mean platelet volume as a predictor of cardiovascular risk: a systematic review and meta-analysis. J Thromb Haemost 2010; 8: 148-56. [CrossRef] 5. Giles H, Smith RE, Martin JF. Platelet glycoprotein IIb/IIIa and size are increased in acute myocardial infarction. Eur J Clin Invest 1994; 24: 69-72. [CrossRef] 6. Schoene NW. Design criteria: tests used to assess platelet function. Am J Clin Nutr 1997; 65: 1665-8. 7. Bath PM, Butterworth RJ. Platelet size: measurement, physiology and vascular disease. Blood Coagul Fibrinolysis 1996; 7: 157-61. [CrossRef] 8. Corash L, Tan H, Gralnick HR. Heterogenity of human whole blood platelet subpopulations. I. Relationship between buoyant density, cell volume, and ultrastructure. Blood 1977; 49: 71-87. 9. Huczek Z, Kochman J, Filipiak KJ, Horszczaruk GJ, Grabowski M, Piatkowski R, et al. Mean platelet volume on admission predicts impaired reperfusion and long-term mortality in acute myocardial infarction treated with primary percutaneous coronary intervention. J Am Coll Cardiol 2005; 46: 284-90. [CrossRef] 10. Matetzky S, Freimark D, Chouraqui P, Novikov I, Agranat O, Rabinowitz B, et al. The distinction between coronary and myocardial reperfusion after thrombolytic therapy by clinical markers of reperfusion. J Am Coll Cardiol 1998; 32: 1326-30. [CrossRef] 11. Claeys MJ, Bosmans J, Veenstra L, Jorens P, De RaedtH, Vrints CJ. Determinants and prognostic implications of persistent ST-segment elevation after primary angioplasty for acute myocardial infarction. Circulation 1999; 99: 1972-7. [CrossRef] 12. Doevendans PA, Gorgels AP, van der Zee R, Partouns J, Bar FW, Wellens HJ. Electrocardiographic diagnosis of reperfusion during thrombolytic therapy in acute myocardial infarction. Am J Cardiol 1995; 75: 1206-10. [CrossRef] 13. Van t’ Hof AWJ, Liem A, de Boer MJ, Zijlstra F. Clinical value of 12-lead electrocardiogram after successful reperfusion therapy for acute myocardial infarction. Zwolle Myocardial infarction Study Group. Lancet 1997; 350: 615-9. [