Journals / Acta Medica Anatolia / 2016 / Cilt: 4 - Sayı: 1

Are Leukocyte and Platelet Indices Associated with Small for Gestational Age Birth and/or Oligohydramnios?

Pages
14–20
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

A new prospective study with larger sample size may present more definitive results.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:ntroduction: To investigate whether certain leukocyte and platelet indices predict Small for Gestational Age (SGA) birth and/ or oligohydramnios.
📊
Key Findings & Data:Materials and Methods: In this retrospective study, 408 pregnant women were included, who didn’t have foreknown systemic diseases and other risk factors like drug use, smoking.
💡
Conclusion & Impact:A new prospective study with larger sample size may present more definitive results.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

ntroduction: To investigate whether certain leukocyte and platelet indices predict Small for Gestational Age (SGA) birth and/ or oligohydramnios. Materials and Methods: In this retrospective study, 408 pregnant women were included, who didn’t have foreknown systemic diseases and other risk factors like drug use, smoking. Patients diagnosed with SGA birth (Group-I, n=59), SGA birth and oligohydramnios (Group-II, n=46), solely oligohydramnios (Group-III, n=23) and control group (Group-IV, n=280, matched for maternal age and body mass index) were selected from medical records. Leukocyte and platelet indices in first trimester and third trimester, demographic and obstetric data were obtained from medical records. Then, groups were compared. Results: Maternal ages and body mass indices were similar among groups. Total leukocyte, neutrophil, lymphocyte and platelet counts, platelet indices (p<0.001), neutrophil to lymphocyte ratios (p<0.001) were significantly different between first and third trimester values in all patients. Platelet distribution width values of group-II in both trimester were significantly higher than ones of group-IV. Conclusion: Most hematologic parameters were not associated with SGA birth and/or oligohydramnios, but it was clarified that they differ significantly between first and third trimester. A new prospective study with larger sample size may present more definitive results.

🔖

Cite This Article

ERSOY, A. Ö., ÖZLER, S., ÖZTAŞ, E., ERSOY, E., KIRBAŞ, A., DANIŞMAN, N. (2016). Are Leukocyte and Platelet Indices Associated with Small for Gestational Age Birth and/or Oligohydramnios?. Acta Medica Anatolia, Cilt: 4 - Sayı: 1, 14–20. https://ajindex.com/articles/142621

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (11)

  1. Battaglia FC, Lubchenco LO. A practical classification of newborn infants by weight and gestational age. J Pediatr 1967; 71: 59-163
  2. Chauhan SP, Gupta LM, Hendrix NW, Berghella V. Intrauterine growth restriction: comparison of American College of Obstetricians and Gynecologists practice bulletin with other national guidelines. Am J Obstet Gynecol 2009; 200: 409.e1–6
  3. Mayer C, Joseph KS. Fetal growth: a review of terms, concepts and issues relevant to obstetrics. Ultrasound Obstet Gynecol 2013; 41: 136–145 4. Locatelli A, Vergani P, Toso L, Verderio M, Pezzullo JC, Ghidini A. Perinatal outcome associated with oligohydramnios in uncomplicated term pregnancies. Arch Gynecol Obstet 2004; 269: 130-3
  4. Johnston TA, Greer IA, Dawes J, Calder AA. Neutrophil activation in small for gestational age pregnancies. Br J Obstet Gynaecol 1991; 98: 105-6
  5. Neyzi O, Gunoz H, Furman A, Bundak R, Gokcay G, Darendeliler F, et al. Weight, height, head circumference and body mass index references for Turkish children. Turkish Pediatric Journal 2008; 51: 1-14
  6. Werner EF, Savitz DA, Janevic TM, Ehsanipoor RM, Thung SF, Funai EF, et al. Mode of delivery and neonatal outcomes in preterm, small-for-gestational-age newborns. Obstet Gynecol 2012; 120: 560-4
  7. Fratelli N, Valcamonico A, Prefumo F, Pagani G, Guarneri T, Frusca T. Effects of antenatal recognition and followup on perinatal outcomes in small-for-gestational age infants delivered after 36 weeks. See comment in PubMed Commons belowActa Obstet Gynecol Scand 2013; 92: 223-9
  8. Varma TR, Bateman S, Patel RH, Chamberlain GV, Pillai U. Ultrasound evaluation of amniotic fluid: outcome of pregnancies with severe oligohydramnios. Int J Gynaecol Obstet 1988; 27: 185-92
  9. Abbassi-Ghanavati M, Greer LG, Cunningham FG. Pregnancy and laboratory studies: a reference table for clinicians. Obstet Gynecol 2009; 114: 1326-31 11. Gordon MC. Maternal Physiology. In: Gabbe SG, Niebyl JR, Simpson JL, Landon MB, Galan HL, Jauniaux ERM et al. Obstetrics: Normal and Problem Pregnancies, Sixth edition. Philadelphia. Saunders, an imprint of Elsevier Inc; 2012. p: 53
  10. Harita N, Kariya M, Hayashi T, Sato KK, Nakamura K, Endo G, et al. Increment of absolute neutrophil count in the third trimester and increased risk of small-for-gestational-age birth: Hirakata Risk Associated with Pregnancy Assessment Research (HIRAPAR). Eur J Obstet Gynecol Reprod Biol 2012; 164: 30-4
  11. Pitkin R, Witte D. Platelet and leukocyte counts in pregn