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Journals / Akdeniz Tıp Dergisi / 2019 / Cilt: 5 - Sayı: 3

Two Sibling Cases who were Diagnosed with Sjögren Syndrome and were Positive for Anti-DFS70 Antibodies

Anti-DFS70 Antikor Pozitifliği Saptanan ve Sjögren Sendromu Tanısı Alan İki Kardeş

Sevcan UĞUR
Cahit KAÇAR
Pages
545–547
Publication Date
2022-10-11
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article, we report two sisters who were diagnosed with Sjögren syndrome and had anti-DFS70 antibodies

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Sjögren syndrome is a systemic autoimmune disease and causes sicca symptoms.
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Key Findings & Data:Anti-dense fine speckled 70 Anti-DFS70 antibodies are common among ANA-positive healthy individuals.
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Conclusion & Impact:In this article, we report two sisters who were diagnosed with Sjögren syndrome and had anti-DFS70 antibodies
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Sjögren sendromu · Anti-DFS70 · ANA

Abstract

Sjögren syndrome is a systemic autoimmune disease and causes sicca symptoms. Patients with Sjögren syndrome can also have relatives with Sjögren syndrome. Anti-dense fine speckled 70 Anti-DFS70 antibodies are common among ANA-positive healthy individuals. In this article, we report two sisters who were diagnosed with Sjögren syndrome and had anti-DFS70 antibodies

Özet

Sjögren sendromu sistemik otoimmün bir hastalıktır ve sicca semptomlarına neden olur. Sjögren sendromlu hastaların Sjögren sendromlu yakınları olabilir. Anti-yoğun ince benekli 70 Anti-DFS70 antikor pozitifliği anti nükleer antikor pozitif ANA sağlıklı bireylerde sık görülür. Biz bu raporda, anti-DFS70 antikoru pozitifliği olmasına rağmen Sjögren sendromu tanısı alan iki kız kardeşi sunmayı amaçladık

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Cite This Article

UĞUR, S., KAÇAR, C. (2022). Two Sibling Cases who were Diagnosed with Sjögren Syndrome and were Positive for Anti-DFS70 Antibodies. Akdeniz Tıp Dergisi, Cilt: 5 - Sayı: 3, 545–547. https://ajindex.com/articles/434370

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References (10)

  1. Brito-Zerón P, Baldini C, Bootsma H, Bowman SJ, Jonsson R, Mariette X, Sivils K, Theander E, Tzioufas A, Ramos-Casals M. Sjögren syndrome. Nat Rev Dis Primers 2016;2:16047 Soto-Cárdenas MJ, Gandía M, Brito-Zerón P, Arias MT, Armiger N, Bové A, Bosch X, Retamozos S, Akusbi M, Perez-D-Lis M, Gueitasi H, Kostov B, Perez- Alvarez, Siso- Almirall A, Lozano F, Ramos-Casals M. Etiopathogenic role of surfactant protein d in the clinical and immunological expression of primary Sjögren syndrome. J Rheumatol 2015;42(1):111- 8. Lichtenfeld JL, Kirschner RH, Wiernik PH. Familial Sjögren’s syndrome with associated primary salivary gland lymphoma. Am J Med 1976;60(2):286-92.
  2. Lee H, Kim Y, Han K, Oh EJ. Application of anti-DFS70 antibody and specific autoantibody test algorithms to patients with the dense fine speckled pattern on HEp-2 cells. Scand J Rheumatol 2016;45(2):122-8.
  3. Lichtenfeld JL, Kirschner RH, Wiernik PH. Familial Sjogren’s syndrome with associated primary salivary gland lymphoma. Am J Med 1976;60:286-92.
  4. Sabio JM, Milla E, Jimenez-Alonso J. A multicase family with primary Sjogren’s syndrome. J Rheumatol 2001;28:1932-4.
  5. Boling EP, Wen J, Reveille JD, Bias WB, Chused TM, Arnett FC. Primary Sjogren’s syndrome and autoimmune hemolytic anemia in sisters: A family study. Am J Med 1983;74:1066-71.
  6. Kuo CF, Grainge MJ, Valdes AM, See LC, Luo SF, Yu KH, Zhang W, Doherty M. Familial risk of Sjögren’s syndrome and co-aggregation of autoimmune diseases in affected families: A nationwide population study. Arthritis Rheumatol 2015;67(7):1904-12.
  7. Michael Mahler, Pier-Luigi Meroni, Xavier Bossuyt, Marvin J. Fritzler current concepts and future directions for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies. J Immunol Res 2014;2014:315179. Seelig CA, Bauer O, Seelig HP. Autoantibodies against DFS70/LEDGF exclusion markers for systemic autoimmune rheumatic diseases (SARD). Clin Lab 2016;62(4):499-517.
  8. Shovman O, Gilburd B, Chayat C, Amital H, Langevitz P, Watad A, Guy A, Perez D, Azoulay D, Blank M, Segal Y, Bentow C, Mahler M, Shoenfeld Y Prevalence of anti- DFS70 antibodies in patients with and without systemic autoimmune rheumatic diseases. Clin Exp Rheumatol 2018;36(1):121-6.
  9. Watanabe A, Kodera M, Sugiura K, Usuda T, Tan EM, Takasaki Y, Tomita Y, Muro Y. Anti-DFS70 antibodies in 597 healthy hospital workers. Arthritis Rheum 2004;50(3):892-900.
  10. Muro Y, Ogawa Y, Sugiura K, Tomita Y. HLA-associated production of anti-DFS70/LEDGF a