Journals / Adnan Menderes Üniversitesi Tıp Fakültesi Dergisi / 2003 / Cilt: 4 - Sayı: 3

Comparison of the efficency of dexamethasone and droperidole in the prevention of postoperative nausea and vomiting

Postoperatif bulantı-kusmanın önlenmesinde deksametazon ve droperidol'ün etkilerinin karşılaştırılması

Pages
17–20
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

There was no difference in analgesic requirement and side effects between the study groups.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: We compared the antiemetic effect of dexametasone with droperidole in patients who had undenvent laparascopic cholecystetomy.
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Key Findings & Data:Materials ve methods: 40 patients were randomly divided into two groups with 20 patients in each group.
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Conclusion & Impact:There was no difference in analgesic requirement and side effects between the study groups.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: We compared the antiemetic effect of dexametasone with droperidole in patients who had undenvent laparascopic cholecystetomy. Materials ve methods: 40 patients were randomly divided into two groups with 20 patients in each group. Group DHBP (Droperidole), received 1.25 mg droperidole IV and Group D (Dexamethasone), received 5 mg dexamethasone IV ten minutes before extubation. Results: Nausea-vomiting score was not statistically different betweenthe study groups.The incidence of nausea in group D was found to be more frequent in comparison to group DHBP within a 24 hour period although this was not statistically significant. Additional antiemetic requirement was more in Group D compared to Group DHBP and this was not statistically signifıcant. There was no difference in analgesic requirement and side effects between the study groups.

Özet

Amaç: Genel anestezi ile laparoskopik kolesistektomi girişimi geçirecek hastalarda POBK'yı önlemede deksametazonun etkinliğini diğer bir antiemetik ajan olan droperidol ile karşılaştırarak araştırmayı amaçladık.Gereç ve Yöntem: Çalışmamızda; ASA I-II grubundan rastgele 40 hasta 20'şer kişilik iki gruba ayrıldı. Grup DHBP (Droperidol), ekstübasyondan l O dk. önce l .25 mg droperidol, Grup D (Deksametazon), ekstübasyondan l O dk. önce 5 mg deksametazon iv yapıldı. Bulgular: Grupların bulantı-kusma skoru açısından karşılaştırılmasında istatistiksel fark bulunmadı. 24 saatlik periyotta bulantı görülme sıklığı Grup D'de Grup DHBP'e göre artmışken, istatistiksel anlamlılık bulunmamaktaydı. Ek antiemetik gereksinimi; Grup D'de Grup DHBP'e göre artmıştı ancak, istatistiksel olarak anlamlı fark yoktu. Analjezi gereksinimi ve yan etkiler açısından gruplar arası istatistiksel anlamlı fark belirlenmedi. Sonuç: Çalışmamız; POBK'nın önlenmesinde tek doz 5 mg deksametazonun kullanılabileceğini göstermiştir.

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Cite This Article

AKÇABAY, M., ARSLAN, M., GÜNGÖR, İ., ÇEKMEN, N. (2022). Comparison of the efficency of dexamethasone and droperidole in the prevention of postoperative nausea and vomiting. Adnan Menderes Üniversitesi Tıp Fakültesi Dergisi, Cilt: 4 - Sayı: 3, 17–20. https://ajindex.com/articles/429110

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