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Journals / Adnan Menderes Üniversitesi Tıp Fakültesi Dergisi / 2005 / Cilt: 6 - Sayı: 3

Effects of esmolol on hemodynamic responses to endotracheal intubation

ndEndotrakeal entübasyon sırasında oluşan hemodinamik değişikliklere esmololün etkisi

Mustafa OĞURLU
Feray GÜRSOY
Bakiye UĞUR
Erdal GEZER
Pages
23–28
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In Group E, HR decreased after induction, in 3rd, 5th, 7th, and 10th minutes (P

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: To evaluate the efficacy of esmolol in modifying hemodynamic response to laryngoscopy and endotracheal intubation.
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Key Findings & Data:Materials and methods: ASA I-II 60 subjects, aged between 20-50 years, were included in this prospective, randomized and single-blind study.
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Conclusion & Impact:In Group E, HR decreased after induction, in 3rd, 5th, 7th, and 10th minutes (P
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Objective: To evaluate the efficacy of esmolol in modifying hemodynamic response to laryngoscopy and endotracheal intubation. Materials and methods: ASA I-II 60 subjects, aged between 20-50 years, were included in this prospective, randomized and single-blind study. Patients were divided into two groups. Group Esmolol(Group E) and Group Control (Group C) received IV bolus of esmolol 1.5 mg/kg and %5 dextrose 5 cc respectively, 2 minutes before laryngoscopy and intubation. We recorded heart rates (HR), mean arterial pressures (MAP), and rate pressure products (RPP) preoperatively, after induction and intubation and in 1st, 3rd, 5th, 7th , and 10th minutes after intubation.Results: In Group C, HR decreased after induction in 5th, 7th, and 10th minutes, whereas it increased after intubation. In Group E, HR decreased after induction, in 3rd, 5th, 7th, and 10th minutes (P

Özet

Amaç: Çalışmamızın amacı laringoskopi ve endotrakeal entübasyona yanıt olarak oluşan taşikardi ve hipertansiyonu baskılamada, bir beta bloker olan esmolol'ün etkilerini araştırmaktır. Gereç ve yöntem: Çalışma prospektif, randomize, tek kör olarak düzenlendi,ASAI-II, 20-50 yaş arası 60 olgu 2 gruba ayrılarak yapıldı. Grup Esmolol'e (Grup E) esmolol (Brevibloc®) 1.5 mg/kg, Grup Kontrol'e (Grup K)%5 dekstroz 5 cc, laringoskopi ve entübasyondan 2 dakika önce I.V bolus verildi. Preoperatif, indüksiyondan sonra, entübasyonun ardından ve 1., 3., 5., 7., 10. dakikalarda kalp atımhızı (KAH), ortalama arter basıncı (OAB) ve hız basınç ürünü (RPP) değerleri kaydedildi.Bulgular: Grup K'da KAH bazal değeri ile karşılaştırıldığında; indüksiyondan sonra ,5., 7., 10. dk'da anlamlı düşme, entübasyondan sonra ise anlamlı yükselme, Grup E'de ise; indüksiyondan sonra, 3., 5., 7., 10. dk'da anlamlı düşme saptandı (P

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Cite This Article

OĞURLU, M., GÜRSOY, F., UĞUR, B., GEZER, E. (2022). Effects of esmolol on hemodynamic responses to endotracheal intubation. Adnan Menderes Üniversitesi Tıp Fakültesi Dergisi, Cilt: 6 - Sayı: 3, 23–28. https://ajindex.com/articles/429046

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