Journals / Adnan Menderes Üniversitesi Tıp Fakültesi Dergisi / 2011 / Cilt: 12 - Sayı: 3

Presentation of a case: Corpus callosum infarct associated with hypoglycemia, presenting with psychiatric finding

Psikiyatrik bulgular ile prezente olan hipoglisemi ile ilişkili korpus kallosum infarktı: Olgu sunumu

Pages
45–48
Publication Date
2022-10-10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This case was considered interesting because of the temporal association between corpus callosum infarct and psychiatric symptoms in the context of coexistent hypoglycemia and left anterior cerebral artery occlusion.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A 54 years old female patient, presenting with psychiatric symptoms, after which corpus callosum infarct was detected is presented with the clinical, laboratory and radiological findings here.
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Key Findings & Data:The patient, who did not have any psychiatric complaints before was evaluated because of personality changes and sleepy state starting 3 days before and disturbance in gait and speech of one day's duration.
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Conclusion & Impact:This case was considered interesting because of the temporal association between corpus callosum infarct and psychiatric symptoms in the context of coexistent hypoglycemia and left anterior cerebral artery occlusion.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

A 54 years old female patient, presenting with psychiatric symptoms, after which corpus callosum infarct was detected is presented with the clinical, laboratory and radiological findings here. The patient, who did not have any psychiatric complaints before was evaluated because of personality changes and sleepy state starting 3 days before and disturbance in gait and speech of one day's duration. Previously she had a diagnosis of diabetes mellitus. Blood glucose was 45 mg/dL. An increase in signal intensity reciprocal to ADC in the corpus callosum was detected in cerebral diffusion magnetic resonance imaging (MRI). The psychiatric findings in this case were considered as “acute and temporary schizoid personality disorder” that may be explained by an underlying organic cause according to DSM-IV. The clinical symptoms that arise from corpus callosum abnormalities are variable. A psychiatric picture develops in approximately one thirds of the cases. On the other hand, corpus callosum infarct presenting with pure psychiatric findings are rarely observed in the literature. This case was considered interesting because of the temporal association between corpus callosum infarct and psychiatric symptoms in the context of coexistent hypoglycemia and left anterior cerebral artery occlusion.

Özet

Ellidört yaşında psikiyatrik bulgular ile prezente olan ve korpus kallozum infarktı saptanan bir kadın hasta klinik, laboratuar ve radyolojik bulgular eşliğinde sunuldu. Daha öncesinde herhangi bir psikiyatrik yakınması olmayan hasta 3 gündür olan kişilik değişiklikleri, uyku hali ve bir gün önce başlayan yürüme ve konuşma bozukluğu nedeniyle değerlendirildi. Öncesinde diabetes mellitus tanısı mevcuttu. Kan şekeri 45mg/dL saptandı. Olgunun serebral difüzyon MRG (DWI) incelemesinde Korpus kallozum'da ADC karşılığı olan sinyal artışı izlendi. DSM-IV'e göre olgudaki psikiyatrik bulgular altta yatan organik neden ile açıklanabilecek “akut ve geçici şizoid kişilik bozukluğu” olarak değerlendirildi. Korpus kallo¬zum anormallikleri sonucu gelişen klinik belirtiler değişkenlik göstermektedir. Olguların yaklaşık üçte birinde ise psikiyatrik tablolar gelişmektedir. Ancak saf psikiyatrik bulgular ile başlayan korpus kallozum infarktı literatürde nadiren gözlenmektedir. Bu olgu hipoglisemiyle birliktelik gösteren sol anterior serebral arter oklüzyonu zemininde korpus kallozum infarktı ve psikiyatrik semptomlar arasındaki zamansal ilişki nedeniyle ilginç bulunmuştur.

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Cite This Article

GÜLER, S., AYGÜN, M. S. (2022). Presentation of a case: Corpus callosum infarct associated with hypoglycemia, presenting with psychiatric finding. Adnan Menderes Üniversitesi Tıp Fakültesi Dergisi, Cilt: 12 - Sayı: 3, 45–48. https://ajindex.com/articles/428913

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References (15)

  1. Fundamentals of the nervous system. In: de Groot J, Chusid JG, editors. Correlative neuroanatomy. 21st ed. Prentice- Hall, Sydney, 1991; 12(1):1-5
  2. Hetts SW, Sherr EH, Chao S, Gobuty S, Barkovich AJ. Anomalies of the corpus callosum: an MR analysis of the phenotypic spectrum of associated malformations. AJR Am J Roentgenol 2006;187(5):1343-8
  3. Ferrante L, Mastronardi L, Acqui M, Fortuna A. Mutism after posterior fossa surgery in children. J Neurosurg 1990;72(6):959-63
  4. Josse G, Seghier ML, Kherif F, Price CJ. Explaining function with anatomy: language lateralization and corpus callosum size. J Neurosci 2008;28(52):14132-9
  5. Marangolo P, De Renzi E, Di Pace E, Ciurli P, Castriota- Skandenberg A. Let not thy left hand know what thy right hand knoweth. The case of a patient with an infarct involving the callosal pathways. Brain 1998;121(8):1459-67
  6. Sauerwein H, Lassonde MC. Intra- and interhemispheric processing of visual information in callosal agenesis. Neuropsychologia 1983;21(2):167-71
  7. Sauerwein HC, Lassonde MC, Cardu B, Geoffroy G. Interhemispheric integration of sensory and motor functions in agenesis of the corpus callosum. Neuropsychologia 1981;19(3):445-54
  8. Forget J, Lippé S, Lassonde M. Perceptual priming does not transfer interhemispherically in the acallosal brain. Exp Brain Res 2009;192(3):443-54
  9. Rosenberg DR, Keshavan MS, Dick EL, Bagwell WW, MacMaster FP, Birmaher B. Corpus callosal morphology in treatment-naive pediatric obsessive compulsive disorder. Prog Neuropsychopharmacol Biol Psychiatry 1997;21(8):1269-83
  10. Fitzgerald KD, MacMaster FP, Paulson LD, Rosenberg DR. Neurobiology of childhood obsessive-compulsive disorder. Child Adolesc Psychiatr Clin N Am 1999;8(3):533-75
  11. Coffman JA, Bornstein RA, Olson SC, Schwarzkopf SB, Nasrallah HA. Cognitive impairment and cerebral structure by MRI in bipolar disorder. Biol Psychiatry 1990;27(11):1188-96
  12. Bellani M, Marzi CA, Savazzi S, Perlini C, Cerruti S, Ferro A, et al. Laterality effects in schizophrenia and bipolar disorder. Exp Brain Res 2010; 201(2):339-44
  13. Hauser P, Dauphinais ID, Berrettini W, DeLisi LE, Gelernter J, Post RM. Corpus callosum dimensions measured by magnetic resonance imaging in bipolar affective disorder and schizophrenia. Biol Psychiatry 1989; 26(7): 659-68
  14. Taylor M, David AS. Agenesis of the corpus callosum: A United Kingdom series of 56 cases. J Neurol Neurosurg Psychiatry 1998; 64(1):131-4
  15. Jeeves MA. Agenesis of the corpus