AI Summary & Key Takeaways
AI InsightIn addition, it was found that the population was not at Hardy-Weinberg equilibrium in terms of related SNP genotypes.
📌 3 Key Takeaways
Abstract
In this study, Stearoyl CoA Desaturase (SCD) gene polymorphism was determined in Hereford cattle breed. A702G, T762C and C878T single nükleotid polymorfphisms (SNPs) have been identified based on DNA sequence information of exon V region in SCD gene. AA, AG and GG genotype frequencies were 20.69%, 44.83% and 34.45% in A702G region, and TT, TC and CC genotype frequencies were 13.79%, 62.07% and 24.14% T762C region, and CC, CT and TT genotype frequencies were %44.83, 31.03 and 24.14 in C878T region, respectively. In addition, A and G allele frequencies were 0.431 and 0.569 in A702G region, T and C allele frequencies were 0.448 and 0.552 in T762C region, and C and T allele frequencies were 0.603 and 0.397 in C878T region, respectively. In addition, it was found that the population was not at Hardy-Weinberg equilibrium in terms of related SNP genotypes.
Özet
Bu çalışmada, Hereford ırkı sığır populasyonunda Stearoyl CoA Desaturase (SCD) gen polimorfizmi belirlenmiştir. SCD geni ekson V bölgesi gen dizi bilgilerine göre A702G, T762C ve C878T tek nükleotid polimorfizmleri (SNP) tespit edilmiştir. A702G bölgesinde AA, AG ve GG genotiplerinin frekansları sırasıyla; %20.69, 44.83 ve 34.45, T762C bölgesinde TT, TC ve CC genotiplerinin frekansları sırasıyla; %13.79, 62.07 ve 24.14, C878T bölgesinde CC, CT ve TT genotiplerinin frekansları sırasıyla; %44.83, 31.03 ve 24.14 olarak hesaplanmıştır. Bununla beraber, A702G bölgesinde A ve G allel frekansları 0.431 ve 0.569, T762C bölgesinde T ve C allel frekansları 0.448 ve 0.552, C878T bölgesinde C ve T allel frekansları 0.603 ve 0.397'dir. Ayrıca ilgili SNP’ler bakımından populasyonun Hardy-Weinberg dengesinde olmadığı belirlenmiştir (P>0.05).