Journals / Hitit Medical Journal / 2021 / Cilt: 3 - Sayı: 3

Correlation between body mass index and erythrocyte sedimentation rates in healthy participants

Sağlıklı İnsanlarda Vücut Kitle İndeksi ile Sedimantasyon Arasındaki İlişki

Pages
82–87
Publication Date
2021-10-14
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: According to the results of this study, ESR is a parameter associated with BMI and it may reflect the magnitude of inflammation taking place in obesity.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Erythrocyte sedimentation rate (ESR) is a cheap, fast and readily available test and its still being used for many medical conditions in order to help diagnosis and evaluation of diseases.
📊
Key Findings & Data:It has been conducted in a university hospital with people admitting to internal medicine outpatient clinics between January 2020 and December 2020.
💡
Conclusion & Impact:Conclusion: According to the results of this study, ESR is a parameter associated with BMI and it may reflect the magnitude of inflammation taking place in obesity.
🔬Design:Research Article
📍Scope:2020 Verileri
⚙️Variables:Beden kitle indeksi · HDL · Lipoprotein

Abstract

Objective: Erythrocyte sedimentation rate (ESR) is a cheap, fast and readily available test and its still being used for many medical conditions in order to help diagnosis and evaluation of diseases. In this study, association of ESR, cholesterol levels and monocyte to high density lipoprotein ratio (MHR) with body mass index were inspected in healthy population. Material and Method: This study is an observational, retrospective study. It has been conducted in a university hospital with people admitting to internal medicine outpatient clinics between January 2020 and December 2020. Demographic characteristics, body mass indexes and laboratory parameters of 689 patients were evaluated. Participants were divided into three groups according to body mass indexes; Group 1 (normal weight), Group 2 (overweight), Group 3 (obese). Data obtained from three groups were compared. Results: There were significant associations between body mass index and height, weight, ESR, glucose, monocyte counts, total cholesterol, low density lipoprotein, Non-HDL cholesterol and MHR among groups. ESR was significantly higher in women compared to men. There were significant correlations between body mass index and ESR (r=0.346, p=0.001), glucose (r=0.239, p=0.001) and monocyte count (r=0.096, p=0.013). Conclusion: According to the results of this study, ESR is a parameter associated with BMI and it may reflect the magnitude of inflammation taking place in obesity. ESR was used for more than a century in evaluation of diseases and it still has a place in different medical disorders.

Özet

Amaç: Uzun yıllardır kullanılan ucuz, kolay ve hızlı bir test olan sedimantasyon hala birçok durumda tanıya yardımcı olmaktadır. Bu çalışmada, sağlıklı bireylerde sedimantasyon, kolesterol değerleri ve monosit yüksek dansiteli lipoprotein oranı (MHR) ile vücut kitle indeksi arasındaki ilişki değerlendirilmiştir. Gereç ve Yöntem: Ocak 2020 ile Aralık 2020 tarihleri arasında; iç hastalıkları kliniğine belirgin şikayeti olmadan, rutin sağlık kontrolü ve check-up için başvuran 689 sağlıklı bireylerin sonuçları retrospektif olarak değerlendirilmiştir. Hastaların demografik özellikleri, vücut kitle indeksi ve kan parametreleri değerlendirilmiştir. Katılımcılar; vücut kitle indeksine göre; Grup 1 (normal kilolu), Grup 2 (aşırı kilolu) ve Grup 3 (obez) olarak sınıflandırılmıştır. Bulgular: Gruplar arasında; vücut kitle indeksi ile; boy, kilo, sedimantasyon değeri, glikoz, monosit sayısı, total kolesterol, düşük dansiteli lipoprotein, yüksek dansiteli lipoprotein dışı kolesterol ve MHR arasında anlamlı bir ilişki saptanmıştır. Kadınların sedimantasyon değeri erkeklerden anlamlı olarak fazla saptanmıştır. Vücut kitle indeksi ile sedimantasyon değeri (r=0.346, p=0.001), glikoz (r=0.239, p=0.001) ve monosit sayısı (r=0.096, p=0.013) arasında anlamlı bir korelasyon bulunmuştur. Sonuç: Bu çalışmanın neticelerine göre sedimantasyon hızı sağlıklı bireylerde VKI ile ilişkili bir parametre olarak sağlıklı bireylerde inflamasyon şiddetini göstermek için kullanılabilir. Sedimantasyon değeri yüzyıl önce bulunmasına rağmen kullanışlılığını devam ettirmektedir.

🔖

Cite This Article

ALANLI, R., KÜÇÜKAY, M. B., YALÇIN, K. S. (2021). Correlation between body mass index and erythrocyte sedimentation rates in healthy participants. Hitit Medical Journal, Cilt: 3 - Sayı: 3, 82–87. https://ajindex.com/articles/421159

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. Jou JM, Lewis SM, Briggs C et al. ICSH review of the measurement of the erythrocyte sedimentation rate. Int J Lab Hematol 2011;33:125-132
  2. Samocha-Bonet D, Lichtenberg D, Tomer A et al. Enhanced erythrocyte adhesiveness/aggregation in obesity corresponds to low-grade inflammation. Obes Res 2003;11:403-407
  3. Brigden M. The erythrocyte sedimentation rate. Still a helpful test when used judiciously. Postgrad Med 1998;103:257-262
  4. Asan N. Relationship of Cardiac Structures and Functions with Adiponectin, C-Reactive Protein and Interleukin-6 Levels in Obese Children. J Clin Exp Invest 2017;8:45-51. 5. de Maat MP, Pietersma A, Kofflard M, Sluiter W, Kluft C. Association of plasma fibrinogen levels with coronary artery disease, smoking and inflammatory markers. Atherosclerosis 1996; 121:185-191
  5. Imaizumi K, Shiga T. Effect of immunoglobulins and IgGfragments on the human erythrocyte aggregation, studied by rheoscope combined with image analyzer. Biorheology 1983; 20:569-577
  6. Weng X, Roederer GO, Beaulieu R, Cloutier G. Contribution of acute-phase proteins and cardiovascular risk factors to erythrocyte aggregation in normolipidemic and hyperlipidemic individuals. Thromb Haemost 1998;80:903-908
  7. Choi JW, Pai SH. Influences of hypercholesterolemia on red cell indices and erythrocyte sedimentation rate in elderly persons. Clin Chim Acta 2004;341:117-121
  8. Mottaghi T, Khorvash F, Khorvash F, Maracy M, Kheirrollahi M, Askari G. Association Between BMI and Inflammation Among Diabetic Polyneuropathy Patients. Int J Prev Med 2019;10: 212
  9. Friedrich K, Sommer M, Strobel S et al. Perturbation of the Monocyte Compartment in Human Obesity. Front Immunol 2019;10:1874
  10. Battaglia S, Scialpi N, Berardi E et al. Gender, BMI and fasting hyperglycaemia influence Monocyte to-HDL ratio (MHR) index in metabolic subjects. PLoS One 2020;15:e0231927
  11. Herkiloglu D, Gokce S. Correlation of monocyte/HDL ratio (MHR) with ınflammatory parameters in obese patients diagnosed with polycystic ovary syndrome. Ginekol Pol 2021;92:537-543
  12. Gostynski M, Gutzwiller F, Kuulasmaa K et al. WHO MONICA Project. Analysis of the relationship between total cholesterol, age, body mass index among males and females in the WHO MONICA Project. Int J Obes Relat Metab Disord 2004;28: 1082-1090
  13. Barbalho SM, Tofano RJ, de Oliveira MB et al. HDL-C and nonHDL-C levels are associated with anthropometric and biochemical parameters. J Vasc Bras 2019;18:e20180109
  14. Donma M,