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Journals / Tıp Araştırmaları Dergisi / 2003 / Cilt: 1 - Sayı: 2

The role of lymphocyte subsets CD4 and CD8 in differential diagnosis of pleural effusions

Lenfosit alt tiplerinden CD4 ve CD8'in plevra sıvılarının ayırıcı tanısındaki rolü

Haluk DÜLGER
Bülent ÖZBAY
Cengizhan SEZGİ
Ayten İŞLEK
Reha ERKOÇ
Kürşat UZUN
Pages
23–26
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Contusions: In conclusion plevral CD4 measurament may have a role in the differential diagnosis of pleural effusion due to tuberculosis or pneumonia.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: Tuberculosis pleurisy develops by delayed type hypersensitivitiy reaction.
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Key Findings & Data:Plevral CD4 was found to be increased when compared to peripheral blood in different studies.
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Conclusion & Impact:Contusions: In conclusion plevral CD4 measurament may have a role in the differential diagnosis of pleural effusion due to tuberculosis or pneumonia.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Antijenler · CD8 · Tüberküloz

Abstract

Objective: Tuberculosis pleurisy develops by delayed type hypersensitivitiy reaction. Plevral CD4 was found to be increased when compared to peripheral blood in different studies. In this study, the role of CD4 and CDS ratios in pleural effusion and peripheral blood was investigated in the dif-ferential diagnosis of pleural effusion. Methods: Eighty eight patients with pleural effusion were included and divided in to four groups (1- Tuberculous pleurisy, 2-Parapneumonic effusion, 3-Malignancy, 4-Transudate). Results: In tuberculosis group, mean serum CD4 and CDS, and pleural mean CD4 values were higher when compared to pneumonia group. Additionally, in tuberculosis group plevral CD4 value was higher than the serum CD4. Contusions: In conclusion plevral CD4 measurament may have a role in the differential diagnosis of pleural effusion due to tuberculosis or pneumonia.

Özet

Amaç: Tüberküloz (tb) plörezi gecikmiş tipte bir hipersensitivite reaksiyonu ile meydana gelmektedir. Çeşitli çalışmalarda CD4'ün tb plörezilerde periferik kanla karşılaştırıldığında plevra sıvısında periferik kana göre daha fazla arttığı gösterilmiştir. Bu çalışmada çeşitli nedenler ile plevra sıvısı gelişen olgularda serum ve plevra sıvılarında CD4 ve CD8 bakılarak bunların ayırıcı tanıdaki rolü araştırılmıştır. Gereç ve Yöntem: Çalışmaya 88 plevra sıvılı olgu alınmıştır. Olgular 4 gruba ayrılmıştır (l- tb, 2-parapnömonik efüzyon, 3- malignite, 4- transuda). Bulgular: Çalışmada elde edilen değerlere göre tb plörezilerin ortalama serum CD4, CD8 ve plevra CD4 değerleri pnömonili olguların ortalama değerlerinden istatistiksel olarak yüksekti. Ayrıca tb olguların plevra CD4 değeri serum CD4 değerinden anlamlı derecede yüksekti. Sonuç: Bu değerler tüberküloz ve pnömoniye bağlı plörezilerde plevra CD4 bakılmasının ayırıcı tanıda rolü olabileceğini düşündürmektedir.

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Cite This Article

DÜLGER, H., ÖZBAY, B., SEZGİ, C., İŞLEK, A., ERKOÇ, R., UZUN, K. (2003). The role of lymphocyte subsets CD4 and CD8 in differential diagnosis of pleural effusions. Tıp Araştırmaları Dergisi, Cilt: 1 - Sayı: 2, 23–26. https://ajindex.com/articles/361741

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References (1)

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