Journals / Kulak Burun Boğaz ve Baş Boyun Cerrahisi / 2002 / Cilt: 10 - Sayı: 2

Application of intratympanic gentamicin with ventilation tube in Meniere's disease

Meniere hastalığında ventilasyon tüpü yolu ile intratimpanik gentamisin uygulaması

Pages
63–66
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

As a conclusion; intratympanic gentamicin application recovers vertigo, preserving hearing with a high rate and becomes a considerable treatment choice in semptomatic treatment of Meniere's disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Results of intratympanic gentamicin applications were researched on Meniere's disease diagnosed patients who were résistent to medical treatment.
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Key Findings & Data:Meniere's disease diagnosed 20 patients were applied intratympanic gentamicin with ventilation tube as 0.5 ml ( 20 mg ) and 3 times a day for a total of 60 mg daily.
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Conclusion & Impact:As a conclusion; intratympanic gentamicin application recovers vertigo, preserving hearing with a high rate and becomes a considerable treatment choice in semptomatic treatment of Meniere's disease.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:İlaç uygulama yolları · Kulak · orta

Abstract

Results of intratympanic gentamicin applications were researched on Meniere's disease diagnosed patients who were résistent to medical treatment. Meniere's disease diagnosed 20 patients were applied intratympanic gentamicin with ventilation tube as 0.5 ml ( 20 mg ) and 3 times a day for a total of 60 mg daily. Changes in vertigo and hearing were recorded for 6-16 months after treatment according to the criterias designated by American Academy of Head and Neck Surgery (AAO-HNS ) in 1985. Intratympanic gentamicin treatment resulted to complete vertigo control on %50 of patients, evident control on %25 while resulting to hearing loss on %10. As a conclusion; intratympanic gentamicin application recovers vertigo, preserving hearing with a high rate and becomes a considerable treatment choice in semptomatic treatment of Meniere's disease.

Özet

Meniere hastalığı tanısı konulan ve ilaç tedavisine cevap vermeyen olgularda intratimpanik gentamisin uygulamasının sonuçları araştırıldı. Meniere hastalığı tanısı konulan 20 hastaya ventilasyon tüpü yolu ile 0.5 mi (20 mg) gün aşırı 3 kez toplam doz 60 mg olacak şekilde intratimpanik gentamisin tedavisi uygulandı. Tedavi sonrası 6-16 ay süre ile takip edilen olguların baş dönmesi ve işitmelerindeki değişiklikler Amerikan Kulak Burun Boğaz Baş ve Boyun Cerrahisi Akademisi (AAO-HNS)'nin 1985 de belirlediği kriterlere göre kaydedildi. İntratimpanik gentamisin tedavisi olguların % 50'sinde tam, % 25'inde ise belirgin vertigo kontrolü sağlarken, % 10 olguda işitmenin kötüleştlği görüldü. Sonuç olarak intratimpanik gentamisin uygulaması büyük oranda işitmeyi koruyarak vertigoyu düzeltmekte ve Meniere sendromunun semptomatlk tedavisinde önemli bir tedavi seçeneği oluşturmaktadır.

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Cite This Article

ÜNLÜ, M., YİĞİT, Ö., ÇINAR, U., AKGÜL, G., ALKAN, S., TURGUT, S., DADAŞ, B. (2002). Application of intratympanic gentamicin with ventilation tube in Meniere's disease. Kulak Burun Boğaz ve Baş Boyun Cerrahisi, Cilt: 10 - Sayı: 2, 63–66. https://ajindex.com/articles/346594

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