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Journals / Records of Natural Products / 2017 / Cilt: 11 - Sayı: 3

Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum

Rezzan ALİYAZICIOĞLU
SELİM DEMİR
Merve BADEM
Sıla Özlem ŞENER
Nuriye KORKMAZ
Elif Ayazoğlu DEMİR
UFUK ÖZGEN
ŞENGÜL ALPAY KARAOĞLU
Yüksel ALİYAZICIOĞLU
Pages
270–284
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Dianthus carmelitarum can be considered in the food, cosmetic, and drug industries due to its antioxidant, antimicrobial, and antigenotoxic activities

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, we investigated the phytochemical composition, antioxidant, antimicrobial, and antigenotoxic properties of the aqueous extract of Dianthus carmelitarum for the first time.
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Key Findings & Data:The polyphenolic content and ferric reducing power values of the extract were found 12.6 ± 0.27 mg gallic acid and 238 ± 2.89 μM trolox equivalents per g sample, respectively.
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Conclusion & Impact:Dianthus carmelitarum can be considered in the food, cosmetic, and drug industries due to its antioxidant, antimicrobial, and antigenotoxic activities
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

In this study, we investigated the phytochemical composition, antioxidant, antimicrobial, and antigenotoxic properties of the aqueous extract of Dianthus carmelitarum for the first time. The phenolic and volatile compounds, antioxidant, antimicrobial and antigenotoxic activities of the extract were determined by HPLC and SPME-GC-FID/MS, spectrophotometric, agar well diffusion methods and comet assay, respectively. The polyphenolic content and ferric reducing power values of the extract were found 12.6 ± 0.27 mg gallic acid and 238 ± 2.89 μM trolox equivalents per g sample, respectively. Syringaldehyde and chlorogenic acid were detected as major phenolic compounds, while terpenes were determined as major volatile compound. Dianthus carmelitarum extract especially exhibited moderate antimicrobial activity against Mycobacterium smegmatis. Extract reduced H2O2-induced DNA damage in a concentration dependent manner in fibroblast cells compared to positive control (only 20 μM H2O2 treatment). Dianthus carmelitarum can be considered in the food, cosmetic, and drug industries due to its antioxidant, antimicrobial, and antigenotoxic activities

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Cite This Article

ALİYAZICIOĞLU, R., DEMİR, S., BADEM, M., ŞENER, S. Ö., KORKMAZ, N., DEMİR, E. A., ÖZGEN, U., KARAOĞLU, Ş. A., ALİYAZICIOĞLU, Y. (2017). Antioxidant, Antigenotoxic, Antimicrobial Activities and Phytochemical Analysis of Dianthus carmelitarum. Records of Natural Products, Cilt: 11 - Sayı: 3, 270–284. https://ajindex.com/articles/308635

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