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Journals / Records of Natural Products / 2021 / Cilt: 15 - Sayı: 2

A New Alkaloid Glycoside from the Stems of Zanthoxylum dissitum Hemsl.

Xian WEI
Yang TAN
Yuhe SHI
Yuan YUAN
Shunmin LI
Pages
76–81
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Compounds 1-3, 6 and 7 showed significant inhibition activities with IC50 values of 26.12±0.81, 8.41±0.23, 13.75±0.54, 6.97±0.77, and 5.78±0.42 μM, respectively.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:A new alkaloid glycoside (1) and six known alkaloids (2–7) were isolated from the stems of Zanthoxylum dissitum Hemsl.
📊
Key Findings & Data:The structure of compound 1 was elucidated by UV, IR, 1H NMR, 13C NMR and mass spectroscopic analyses.
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Conclusion & Impact:Compounds 1-3, 6 and 7 showed significant inhibition activities with IC50 values of 26.12±0.81, 8.41±0.23, 13.75±0.54, 6.97±0.77, and 5.78±0.42 μM, respectively.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Özet

A new alkaloid glycoside (1) and six known alkaloids (2–7) were isolated from the stems of Zanthoxylum dissitum Hemsl. The structure of compound 1 was elucidated by UV, IR, 1H NMR, 13C NMR and mass spectroscopic analyses. All compounds obtained in this research were evaluated for their inhibitions against NO release from LPS-activated RAW264.7 macrophages. Compounds 1-3, 6 and 7 showed significant inhibition activities with IC50 values of 26.12±0.81, 8.41±0.23, 13.75±0.54, 6.97±0.77, and 5.78±0.42 μM, respectively.

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Cite This Article

WEI, X., TAN, Y., SHI, Y., YUAN, Y., LI, S. (2021). A New Alkaloid Glycoside from the Stems of Zanthoxylum dissitum Hemsl.. Records of Natural Products, Cilt: 15 - Sayı: 2, 76–81. https://ajindex.com/articles/308575

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