Journals / Turkish Neurosurgery / 2012 / Cilt: 22 - Sayı: 5

Büyük medial sfenoid kanat menenjiyomları: Arka arkaya 127 olguda mikrocerrahi tedavi sonrasında uzun dönemli sonuç ve tümör büyüklüğüyle korelasyon

Large medial sphenoid wing meningiomas: Long-term outcome and correlation with tumor size after microsurgical treatment in 127 consecutive cases

Pages
547–557
DOI
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⚡ TL;DR(Too Long; Didn't Read)

The size of tumor affected the extent of tumor removal determining clinical outcomes including VA improvement and KPS score immediately after surgery; however, it was not correlated with long-term overall outcomes.

📌 3 Key Takeaways

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Objective & Hypothesis:AIM: We present the long-term outcomes as well as their correlation with tumor size in 127 consecutive patients harboring large MSWM after microsurgical treatment.
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Key Findings & Data:MaterIal and Methods: The retrospective analysis of clinical data and follow-up data of 127 microsurgical treated patients with MSWM was performed.
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Conclusion & Impact:The size of tumor affected the extent of tumor removal determining clinical outcomes including VA improvement and KPS score immediately after surgery; however, it was not correlated with long-term overall outcomes.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

AIM: We present the long-term outcomes as well as their correlation with tumor size in 127 consecutive patients harboring large MSWM after microsurgical treatment. MaterIal and Methods: The retrospective analysis of clinical data and follow-up data of 127 microsurgical treated patients with MSWM was performed. The mean maximum diameter of tumors was 5.2cm (ranged 1.5-10.0cm). Results: 104 cases (81.9%) achieved gross total resection. There was no operative mortality. Detailed follow-up data was available in 120 cases for a mean duration of 81.6 months (12-216 months). The permanent morbidity was 14.2%. The mean KPS score 1 year after surgery was 90.6 (ranged 60-100). Among 74 patients of preoperative visual acuity (VA) impairment, postoperative VA improved in 42 cases (56.8%), unchanged in 30 (40.5%), and deteriorated in 2 (2.7%). MR images revealed tumor recurrence after total resection in 10 cases (10.2%) and tumor progression after subtotal resection in 10 cases (45.5%). ConclusIon: Tumor recurrence was the major risk in the long run, thus the initial surgery was extremely important and hence should be aggressive. The size of tumor affected the extent of tumor removal determining clinical outcomes including VA improvement and KPS score immediately after surgery; however, it was not correlated with long-term overall outcomes.

Özet

AMAÇ: Büyük MSWM bulunan arka arkaya 127 olguda mikrocerrahi tedavi sonrasında uzun süreli sonuçları ve tümör büyüklüğüyle korelasyonlarını sunuyoruz. YÖNTEM ve GEREÇLER: MSWM bulunan ve mikrocerrahi ile tedavi edilen 127 hastanın klinik verileri ve takip verilerinin retrospektif analizi yapıldı. Tümörlerin ortalama maksimum çapı 5,2 cm (aralık 1,5 - 10,0 cm) bulundu. BULGULAR: 104 olguda (%81,9) gros total rezeksiyon yapıldı. Operatif mortalite yoktu. Ayrıntılı takip verileri 120 olguda ortalama 81,6 ay (12-216 ay) için mevcuttu. Kalıcı morbidite %14,2 oranında görüldü. Cerrahiden 1 yıl sonra ortalama KPS skoru 90,6 (aralık 60-100) bulundu. Preoperatif görme keskinliği bozukluğu olan 74 hasta içinde postoperatif dönemde görme keskinliği 42 hastada (%56,8) arttı, 30’unda (%40,5) değişmedi ve 2’sinde (%2,7) kötüye gitti. MR görüntüleri total rezeksiyon sonrasında 10 olguda (%10,2) tümör reküransı ve subtotal rezeksiyon sonrasında 10 olguda (%45,5) tümör ilerlemesi gösterdi. SONUÇ: Uzun dönemde temel risk tümör reküransıydı ve bu nedenle ilk cerrahi çok önemlidir ve agresif olmalıdır. Tümör büyüklüğü, tümör çıkarma kapsamını etkileyerek ameliyattan hemen sonra görme keskinliği düzelmesi ve KPS skoru dahil klinik sonuçları etkiledi ancak uzun dönemli genel sonuçlarla korelasyon göstermedi.

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Cite This Article

LIU, D., YUAN, X., LIU, Q., JIANG, X., JIANG, W., PENG, Z., DING, X., LUO, D., YUAN, J. (2012). Büyük medial sfenoid kanat menenjiyomları: Arka arkaya 127 olguda mikrocerrahi tedavi sonrasında uzun dönemli sonuç ve tümör büyüklüğüyle korelasyon. Turkish Neurosurgery, Cilt: 22 - Sayı: 5, 547–557. https://ajindex.com/articles/405529

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References (1)

  1. Abdel-Aziz KM, Froelich SC, Dagnew E, Jean W, Breneman JC, Zuccarello M, van Loveren HR, Tew JM Jr: Large sphenoid wing meningiomas involving the cavernous sinus: Conservative surgical strategies for better functional outcomes. Neurosurgery 54:1375-1383, discussion 1383- 1374, 2004 2. Al-Mefty O: Clinoidal meningiomas. J Neurosurg 73:840-849, 1990 3. al-Mefty O, Ayoubi S: Clinoidal meningiomas. Acta Neurochir Suppl (Wien) 53:92-97, 1991 4. Al-Mefty O, Smith RR: Surgery of tumors invading the cavernous sinus. Surg Neurol 30:370-381, 1988 5. Bassiouni H, Asgari S, Sandalcioglu IE, Seifert V, Stolke D, Marquardt G: Anterior clinoidal meningiomas: Functional outcome after microsurgical resection in a consecutive series of 106 patients. Clinical article. J Neurosurg 111:1078-1090, 2009 6. Behari S, Giri PJ, Shukla D, Jain VK, Banerji D: Surgical strategies for giant medial sphenoid wing meningiomas: A new scoring system for predicting extent of resection. Acta Neurochir (Wien) 150:865-877, discussion 877, 2008 7. Bikmaz K, Mrak R, Al-Mefty O: Management of bone-invasive, hyperostotic sphenoid wing meningiomas. J Neurosurg 107:905-912, 2007 8. Bonnal J, Thibaut A, Brotchi J, Born J: Invading meningiomas of the sphenoid ridge. J Neurosurg 53:587-599, 1980 9. DeMonte F, Smith HK, al-Mefty O: Outcome of aggressive removal of cavernous sinus meningiomas. J Neurosurg 81:245-251, 1994 10. Dufour H, Muracciole X, Metellus P, Regis J, Chinot O, Grisoli F: Long-term tumor control and functional outcome in patients with cavernous sinus meningiomas treated by radiotherapy with or without previous surgery: Is there an alternative to aggressive tumor removal? Neurosurgery 48:285-294, discussion 294-286, 2001 11. Goel A, Gupta S, Desai K: New grading system to predict resectability of anterior clinoid meningiomas. Neurol Med Chir (Tokyo) 40:610-616; discussion 616-617, 2000 12. Iwai Y, Yamanaka K, Ishiguro T: Gamma knife radiosurgery for the treatment of cavernous sinus meningiomas. Neurosurgery 52:517-524, discussion 523-514, 2003 13. Klink DF, Sampath P, Miller NR, Brem H, Long DM: Long-term visual outcome after nonradical microsurgery patients with parasellar and cavernous sinus meningiomas. Neurosurgery 47:24-31, discussion 31-22, 2000 14. Lee JH, Jeun SS, Evans J, Kosmorsky G: Surgical management of clinoidal meningiomas. Neurosurgery 48:1012-1019, discussion 1019-1021, 2001 15. Lee JH, Sade B, Park BJ: A surgical technique for the removal of clinoidal meningiomas. Ne