Journals / Retina-Vitreus / 2010 / Cilt: 18 - Sayı: 2

Intravitreal bevacizumab for the treatment of ecurrent choroidal neovascular membrane secondary to Angioid Streak

Anjioid Streak’a bağlı tekrarlayan koroid neovasküler membran tedavisinde intravitreal bevacizumab

Pages
174–176
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Intravitreal bevacizumab injection will be a promising and primarily applied treatment option for such cases in the future.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Angioid streaks are irregular breaks in the Bruch’s membrane and they predispose to the development of choroidal neovascular membrane (CNVM), which carries a poor visual prognosis.
📊
Key Findings & Data:We report the successful treatment of a 51-year-old woman with CNVM secondary to angioid streak in the right eye who received two doses of intravitreal bevacizumab injections with a one-month interval.
💡
Conclusion & Impact:Intravitreal bevacizumab injection will be a promising and primarily applied treatment option for such cases in the future.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Angioid streaks are irregular breaks in the Bruch’s membrane and they predispose to the development of choroidal neovascular membrane (CNVM), which carries a poor visual prognosis. We report the successful treatment of a 51-year-old woman with CNVM secondary to angioid streak in the right eye who received two doses of intravitreal bevacizumab injections with a one-month interval. Rapid regression of CNVM was observed after the injections. After two months, her visual acuity improved from 0.4 to 1.0 and remained at this level for 10 months. Intravitreal bevacizumab injection will be a promising and primarily applied treatment option for such cases in the future.

Özet

Anjioid streak Bruch membranındaki düzensiz çatlaklar olup görme açısından kötü prognoz taşıyan koroid neovasküler membran (KNVM) gelişimine yatkınlık oluşturur. Biz 51 yaşında kadın olgunun sağ gözünde anjioid streak zemininde gelişen KNVM’nin 1 ay arayla yapılan 2 doz intravitreal bevacizumab enjeksiyonu ile elde edilen başarılı tedaviyi sunacağız. Enjeksiyonlardan sonra KNVM’de hızlı gerileme gözlendi. Olgunun görme keskinliği 2 ay sonra 0.4’ten 1.0’a yükseldi ve 10 ay boyunca bu seviyede kaldı. İntravitreal bevacizumab enjeksiyonu bu tür olgularda gelecek için umut verici ve öncelikli uygulanabilecek bir tedavi yöntemidir.

🔖

Cite This Article

ÖZCURA, F., DÜNDAR, O. S. (2010). Intravitreal bevacizumab for the treatment of ecurrent choroidal neovascular membrane secondary to Angioid Streak. Retina-Vitreus, Cilt: 18 - Sayı: 2, 174–176. https://ajindex.com/articles/308094

References (10)

  1. Gurwood AS, Mastrangelo DL.: Understanding angioid streaks. J Am Optom Assoc. 1997;68:309-324
  2. Lim JI, Bressler NM, Marsh MJ, et al.: Laser treatment of choroidal neovascularization in patients with angioid streaks. Am J Ophthalmol. 1993;116:414-423
  3. Arias L, Pujol O, Rubio M, et al.: Long-term results of photodynamic therapy for the treatment of choroidal neovascularization secondary to angioid streaks. Graefes Arch Clin Exp Ophthalmol. 2006;244:753-757
  4. Aras C, Başerer T, Yolar M, et al.: Two cases of choroidal neovascularization treated with transpupillary thermotherapy in angioid streaks. Retina. 2004;24:801-803
  5. Kwak N, Okamoto N, Wood JM, et al.: VEGF is major stimulator in model of choroidal neovascularization. Invest Ophthalmol Vis Sci. 2000;41:3158-3164
  6. Kır N.: Yaşa bağlı makula dejeneresansında bevacizumab. RetVit. 2007;15(özel sayı):46-49
  7. Chang LK, Spaide RF, Brue C, et al.: Bevacizumab treatment for subfoveal choroidal neovascularization from causes other than age-related macular degeneration. Arch Ophthalmol. 2008;126:941-945
  8. Teixeira A, Moraes N, Farah ME, et al.: Choroidal neovascularization treated with intravitreal injection of bevacizumab (Avastin) in angioid streaks. Acta Ophthalmol Scand. 2006;84:835-836
  9. Şentürk F, Özdemir H, Karaçorlu SA, ve ark.: Angioid streak’e bağlı submaküler koroid neovaskülarizasyonunda intravitreal bevacizumab injeksiyonu. Ret-Vit. 2008;16:278-281
  10. Kovach JL, Schwartz SG, Hickey M, et al.: Thirty-two month follow-up of successful treatment of choroidal neovascularization from angioid streaks with intravitreal bevacizumab. Ophthalmic Surg Lasers Imaging. 2009;40:77-79.