Journals / MN Kardiyoloji / 2004 / Cilt: 11 - Sayı: 4

Evaluation of relationship between functional capacity and right ventricular diastolic function in patients with isolated mitral stenosis and sinus rhythm via tissue doppler

Sinüs ritimli izole mitral darlığında fonksiyonel kapasite ile sağ ventrikül diyastolik fonksiyonları arasındaki ilişkinin doku doppler ile değerlendirilmesi

Pages
266–271
DOI
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Symptomatic patients with isolated mitral stenosis, diastolic functions of right ventricle may deteriorate in presence of normal right ventricular systolic functions.

📌 3 Key Takeaways

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Objective & Hypothesis:Aim: The right ventricular systolic function is an important determinant of clinical symptoms, exercise capacity, pre-operative survival and post-operative outcome in patients with mitral stenosis.
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Key Findings & Data:In presence of normal right ventricular systolic function and sinus rhythm, right ventricular diastolic functions of asymptomatic patients with mitral stenosis of moderate or severe degree were compared to symptomatic ones with similiar features via pulsed wave tissue Doppler echocardiography in this study.
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Conclusion & Impact:Symptomatic patients with isolated mitral stenosis, diastolic functions of right ventricle may deteriorate in presence of normal right ventricular systolic functions.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Diyastol · Mitral kapak darlığı · Sistol

Abstract

Aim: The right ventricular systolic function is an important determinant of clinical symptoms, exercise capacity, pre-operative survival and post-operative outcome in patients with mitral stenosis. No sufficient data is available concerning the effect of right ventricular diastolic function on symptoms of patients with mitral stenosis. In presence of normal right ventricular systolic function and sinus rhythm, right ventricular diastolic functions of asymptomatic patients with mitral stenosis of moderate or severe degree were compared to symptomatic ones with similiar features via pulsed wave tissue Doppler echocardiography in this study. Material and Method: The study included 40 patients with mitral stenosis. Patients were divided into 2 groups according to NYHA class (asymptomatic group NYHA class I, symptomatic group NYHA class II-III). Right ventricular diastolic functions were evaluated via pulsed wave tissue Doppler in terms of isovolumic contraction time (IVCT), systolic wave velocity (S), isovolumic relaxation time (IVRT), early diastolic wave velocity (E), late diastolic wave velocity (A) were calculated right ventricular tricuspid annulus, respectively. Results: Pulsed wave tissue Doppler applied for right ventricular diastolic functions revealed the following: IVCT in group I and group II were 110.5$\pm$8.4 ms and 113.5$\pm$25.4 ms (p>0.05), respectively, while peak amplitude of S wave in group I and group II were found to be 12.1$\pm$1.37 cm/s and 11.38$\pm$1.24 cm/s (p>0.05), respectively. IVRT in group I and group II were 54.21$\pm$11.93 ms, 86.19$\pm$16.23 ms (p<0.0001) respectively, E velocity in group I and group II were 11.68$\pm$1.60 cm/s and 10.25$\pm$2.73 cm/s (p=0.009), respectively. While A velocity in group I and group II were found to be 10.16$\pm$2.14 cm/s and 13.55$\pm$3.35 cm/s (p<0.0001) respectively, resulting in an E/A ratio of 1.18$\pm$0.23 and 0.76$\pm$0.17 (p<0.0001) in group I and group II respectively. Conclusion: In isolated mitral stenosis, pulsed wave tissue Doppler may aid in detection of right ventricular diastolic pathology. Besides systolic functions, diastolic functions of right ventricular plays on important role in occurence of symptoms. Symptomatic patients with isolated mitral stenosis, diastolic functions of right ventricle may deteriorate in presence of normal right ventricular systolic functions.

Özet

Amaç: Mitral darlığında sağ ventrikül sistolik fonksiyonu operasyon öncesi yaşam beklentisi ve operasyon sonrası sonuçlar, egzersiz kapasitesi, klinik semptomların belirlenmesinde önemlidir. Ancak sağ ventrikül diyastolik fonksiyonlarının semptomlara olan etkisi hakkında yeterli bilgi yoktur. Bu çalışmada, sağ ventrikül sistolik fonksiyonları normal sinüs ritimli orta ve şiddetli izole mitral darlığı olan asemptomatik hastalar ile semptomatik hastaların sağ ventrikül diyastolik fonksiyonları pulsed wave doku Doppler ile karşılaştırılmıştır. Gereç ve Yöntem: Çalışmaya Türkiye Yüksek İhtisas Hastanesi'ne başvuran, 40 izole mitral darlıklı hasta alındı. Hastalar New York Kalp Cemiyetinin sınıflandırmasına göre asemptomatik (NYHA klas I) olan ve semptomatik (NYHA klas II ve III) olarak iki gruba ayrıldı. Sağ ventrikül diyastolik fonksiyonları, pulsed wave doku Doppler ile triküspit lateral anulusundan sırasıyla, izovolümik kontraksiyon zamanı (IVKZ), sistolik dalga hızı (S), izovolümik relaksasyon zamanı (IVRZ), erken diyastolik akım hızı (E), geç diyastolik akım hızı (A) elde edildi. Bulgular: Sağ ventrikül diyastolik parametreleri için yapılan pulsed wave doku Doppler bulguları IVKZ grup I'de 110.5$\pm$8.4 ms, grup II için 113.5$\pm$25.4 ms (p>0.05), S dalga tepe amplitüd grup I'de 12.1$\pm$1.37 cm/s, grup II'de 11.38$\pm$1.24 cm/s (p>0.05) saptanmıştır. İVRZ grup I'de 54.21$\pm$11.93 ms, grup II'de 86.19$\pm$16.23 ms (p<0.0001), E hızı grup I'de 11.68$\pm$1.60 cm/s, grup II'de 10.25$\pm$2.73 cm/s (p=0.009), A hızı grup I'de 10.16$\pm$2.14 cm/s, grup II'de 13.55$\pm$3.35 cm/s (p<0.0001), E/A oranı grup I'de 1.18$\pm$0.23, grup II'de 0.76$\pm$0.17 (p<0.0001) olarak anlamlı bulunmuştur. Sonuç: Sonuç olarak pulsed doku Doppler izole mitral darlığında sağ ventrikül diyastolik patolojiyi gösterebilir. İzole mitral darlığında semptomların ortaya çıkmasında sağ ventrikülün sistolik fonksiyonlarının yanısıra diyastolik fonksiyonları da önemlidir. Semptomatik izole mitral darlıklı hastalarda sağ ventrikül sistolik fonksiyonları normal olmasına rağmen diyastolik fonksiyonlarının bozulmuş olabilir.

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Cite This Article

SARIÇAM, E., ÖZBAKIR, C., TÜFEKÇİOĞLU, O., ÖCAL, A., BOZBOĞA, S., YALTA, K., BAŞCIL, S., ERBAŞI, S., SABAH, İ. (2004). Evaluation of relationship between functional capacity and right ventricular diastolic function in patients with isolated mitral stenosis and sinus rhythm via tissue doppler. MN Kardiyoloji, Cilt: 11 - Sayı: 4, 266–271. https://ajindex.com/articles/297659

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