SavedAdd your journal

Journals / MN Kardiyoloji / 2006 / Cilt: 13 - Sayı: 2

Evaluation of diastolic function in amyloidosis with conventional and tissue doppler echocardiography

Amiloidozlu hastalarda diyastolik fonksiyonların konvansiyonel ve doku doppler ekokardiyografiyle değerlendirilmesi

İbrahim ÖZDOĞRU
Ergün SEYFELİ
Ali DOĞAN
Tuğrul İNANÇ
Mustafa GÜR
NİHAT KALAY
Namık Kemal ERYOL
Ramazan TOPSAKAL
Ali ERGİN
Pages
94–97
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Different stages of diastolic dysfunction can be detected with conventional and tissue Doppler echocardiography.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: Cardiac involvement in amyloidosis is frequently observed and causes diastolic dysfunction.
📊
Key Findings & Data:There is a significant correlation between diastolic dysfunction stage and mortality.
💡
Conclusion & Impact:Conclusion: Different stages of diastolic dysfunction can be detected with conventional and tissue Doppler echocardiography.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Amiloidoz · Diyastol · Ekokardiyografi

Abstract

Aim: Cardiac involvement in amyloidosis is frequently observed and causes diastolic dysfunction. There is a significant correlation between diastolic dysfunction stage and mortality. We aimed to evaluate diastolic function in amyloidosis with conventional and tissue Doppler echocardiography. Material and Methods: The study was performed by enrollment of 30 patients with amyloidosis (mean age 41±15 years) and 20 healthy subjects (mean age 43±13 years). Diastolic function parameters were evaluated by conventional and tissue Doppler echocardiography. Results: When the diastolic parameters of left ventricle were evaluated; 8 patients (27.5%) have normal diastolic functions,14 patients (48.2%) have impaired relaxation, 6 patients (20.6%) have pseudonormal pattern, and one patient (3.4%) has restrictive pattern. In tissue Doppler imaging mitral lateral annulus E (m/s) velocity decreased (p<0.01) and A (m/s) and S (m/s) velocities were found similar compared with the control group (p>0.05). Conclusion: Different stages of diastolic dysfunction can be detected with conventional and tissue Doppler echocardiography.

Özet

Amaç: Amiloidozda kardiyak tutulum sık olarak görülmekte ve diyastolik fonksiyon bozukluğuna neden olmaktadır. Diyastolik fonksiyon bozukluğunun evresi ile mortalite arasında sıkı bir ilişki vardır. Çalışmamızın amacı amiloidozlu hastalarda sol ventrikül (SV) diyastolik fonksiyonlarını konvansiyonel ve doku Doppler ekokardiyografiyle (DDE) değerlendirmektir. Gereç ve Yöntem: Bu çalışma amiloidozlu 30 hasta (yaş ortalamaları 41±15 yıl) ve 20 sağlıklı birey (yaş ortalamaları 43±13 yıl) alınarak gerçekleştirildi. Diyastolik fonksiyon parametreleri konvansiyonel ve DDE ile değerlendirildi. Bulgular: Sol ventrikül diyastolik fonksiyon parametreleri incelendiğinde 8 hastada (%27.5) diyastolik fonksiyonlar normal, 14 hastada (%48.2) relaksasyon bozukluk paterni, 6 hastada (%20.6) yalancı normal patern ve bir hastada (%3.4) restriktif patern mevcuttu. Doku Doppler ekokardiyografide mitral lateral annulus E hızı (m/s) kontrol grubuna göre azalmış (p 0.05). Sonuç: Konvansiyonel ve DDE’yle amiloidozlu hastalarda farklı evrelerde diyastolik fonksiyon bozukluğu saptanabilmektedir.

🔖

Cite This Article

ÖZDOĞRU, İ., SEYFELİ, E., DOĞAN, A., İNANÇ, T., GÜR, M., KALAY, N., ERYOL, N. K., TOPSAKAL, R., ERGİN, A. (2006). Evaluation of diastolic function in amyloidosis with conventional and tissue doppler echocardiography. MN Kardiyoloji, Cilt: 13 - Sayı: 2, 94–97. https://ajindex.com/articles/297525

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (12)

  1. Mueller P, Edwards W, Gertz M. Symptomatic Ischemic Heart Disease Resulting from Obstructive Intramural Coronary Amyloidosis. Am J Medicine 2000; 109:181-8.
  2. Kushwaha S, Fallon J, Fuster Valentin. Restrictive cardio myopathy. N Engl J Med 1997; 336:267-74.
  3. Falk R, Plehn J, Deering T, et al. Sensivity and specificity of the echocardiographic features of cardiac amyloidosis. Am J Cardiol 1987; 59:418-22.
  4. Siqueria-Filho A, Cuncha C, Tajik A, Seward J, Schattenberg T, Giuliani E. M-mode and two-dimensional echocardiographic features in cardiac amyloidosis. Circulation 1981; 63:188-96.
  5. Cacoub P, Axler O, De Zuttere D, et al. Amyloidosis and car­ diac involvement. Ann. Med. Interne 2000; 151:611-7.
  6. Falk R, Comenzo R, Skinner I N Engl J Med 1997; 337:898-909.
  7. Demir M, Paydaş S, Cayli M, Akpinar O, Balal M, Acarturk E. Tissue Doppler is a more reliable method in early detection of cardiac dysfunction in patients with AA amyloidosis. Ren Fail. 2005; 27:415-20.
  8. Teichholz L, Kreulen T, Herman MV, Gorlin R. Problems in echocardiographic volume determinations: echocardiographic angiographic correlations in the presence or absence of asy negy. Am J Cardiol. 1976; 37:7-11. Otto CM. Ventricular diastolic filling and function. Textbook of Clinical Echocardiography: Third ed. WB Saunders Company 2004:185. Cueto-Garcia L, Reeder GS, Kyle RA, et al. Echocardiograp­ hic findings in systemic amyloidosis: spectrum of cardiac involve­ ment and relation to survival. J Am Coll Cardiol 1985; 6:737-43.
  9. Hongo M, Kono J, Yamada H, et al. Doppler echocardiograp­ hic assessments of left ventricular diastolic filling in patients with amyloid heart disease. Journal of Cardiology 1991; 21:391-401.
  10. Klein A, Hatle L, Burstow D, et al. Doppler characterization of left ventricular diastolic function in cardiac amyloidosis. J Am Coll Cardiol 1989; 13:1017-26.
  11. Klein A, Tajik A. Doppler assessment of diastolic function in cardiac amyloidosis. Echocardiography 1991; 2:233-51.
  12. Koyama J, Ray-Sequin P, Davidoff R, Falk R. Usefulness of Pulsed Tissue Doppler Imaging for Evaluating Systolic and Dias­ tolic Left Ventricular Function in Patients With AL (Primary) Amy­ loidosis. Am J Cardiol 2002; 89;.1067-71.