Journals / Ondokuz Mayıs Üniv. Diş Hekimliği Derg. / 2007 / Cilt: 8 - Sayı: 2

The role platelet rich plasma in oral and maxilofacial surgery

Oral ve maksillofasiyal cerrahide plateletten zengin plazmanın rolü

Pages
141–146
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this article we describe the use of platelet rich plasma in oral and maxillofacial surgery.

📌 3 Key Takeaways

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Objective & Hypothesis:Platelet rich plasma (PRP), is a new and potentially useful adjunt in oral and maxillofacial surgery.
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Key Findings & Data:They release multiple wound healing growth factors and cytokines such as platelet-derived growth factor (PDGF), transforming growth factor beta 1 (TGF-$1), transforming growth factor beta! (TGF-$2), insulin-like growth factor (IGF), epitermal growth factor (EGF), epithelial cell growth factor (ECGF) and growth factor for hepatocytes.
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Conclusion & Impact:In this article we describe the use of platelet rich plasma in oral and maxillofacial surgery.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Platelet rich plasma (PRP), is a new and potentially useful adjunt in oral and maxillofacial surgery. Platelets are very important in wound healing process. They arrive quickly at the wound site and begin coagulation. They release multiple wound healing growth factors and cytokines such as platelet-derived growth factor (PDGF), transforming growth factor beta 1 (TGF-$1), transforming growth factor beta! (TGF-$2), insulin-like growth factor (IGF), epitermal growth factor (EGF), epithelial cell growth factor (ECGF) and growth factor for hepatocytes. These growth factors are thought to contribute to bone regeneration and increased vascularity. Platelet-rich plasma is used as a source of growth factors to stimulate and accelerate bone formation and soft tissue healing. Early controlled studies indicate that combining platelet-rich plasma with bone grafts significantly enhances the rate of bone formation and maturation. It can be used in combination with different bone grafting materials. In this article we describe the use of platelet rich plasma in oral and maxillofacial surgery.

Özet

Plateletten zengin plazma (PRP), oral ve maksillofasiyal bölgedeki kemik rekonstrüksiyonu cerrahisinde yeni ve potan¬siyel olarak kullanışlı bir seçenektir. Plateletler, yara iyileşmesi için çok önemli hücrelerdir. Yara bölgesine doğru çok hızlı hareket eder ve koagülasyonu başlatırlar. Platelet kaynaklı büyüme faktörü (PDGF), transforming büyüme fak¬törü beta 1 (TGF-$I), transforming büyümü faktörü beta 2 (TGF-$2), insülin benzeri büyüme faktörü (IGF), epidermal büyüme faktörü (EGF), epitelial hücre büyüme faktörü (ECGF) ve hepatositler için büyüme faktörü gibi bir çok yara iyileşmesi büyüme faktörü ve stokin salarlar. Bu büyüme faktörlerinin kemik rejenerasyonu ve kanlanmanın artmasını sağladığı düşünülmektedir. Plateletten zengin plazma kemik formasyonu ve yumuşak doku iyileşmesini stimüle eden büyüme faktör¬lerinin kaynağı olarak kullanılır. Yapılan son çalışmalar plateletten zengin plazma ile kombine edilerek kullanılan kemik greftlerinin kemik formasyonu ve maturasyonu oranını arttırdığını göstermektedir. Plateletten zengin plazma bir çok değişik kemik greft materyali ile kombine olarak kullanılabilir. Bu makalede plateletten zengin plazmanın hazırlanışı ve mak¬sillofasiyal bölgede kullanımı anlatılmaktadır.

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Cite This Article

GÜMGÜM, S., ARIK, A. M. (2007). The role platelet rich plasma in oral and maxilofacial surgery. Ondokuz Mayıs Üniv. Diş Hekimliği Derg., Cilt: 8 - Sayı: 2, 141–146. https://ajindex.com/articles/293192

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