Journals / Ondokuz Mayıs Üniv. Diş Hekimliği Derg. / 2008 / Cilt: 9 - Sayı: 1

Cilinical and histomorphometric comparison of platet pellet/biactive glass combination with or without GTR in the treatment of class II furcation defects in dogs

Köpeklerde oluşturulan sınıf II furkasyon defektlerinin tedavisinde platelet pellet/bioaktif cam kombinasyonunun tek başına veya YDR ile birlikte uygulanmasının klinik ve histomorfometrik olarak karşılaştırılması

Pages
1–9
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: It can be concluded that both PP/BG ve PP/BG/ GTR is effective in treating Class II furcation defects however, GTR increases the regenerative potential with respect to new bone formation.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Aim: The purpose of this study is to compare clinical and histomorphometric effectiveness of platelet pellet/bioaktive glass (PP/BG) and platelet pellet/bioaktive glass/guided tissue regeneration (PP/BG/GTR) in treating Class IIfurcation defects in dogs and to examine the role of GTR in promoting the positive results.
📊
Key Findings & Data:Metarial ard Mettods: Class II furcation lesions (5mm in height, 2 mm in depth) were surgically created on the buccal surface of second, third, and fourth premolars of two quadrants in the maxilla in three adult mongrel dogs weighing about 10 kg.
💡
Conclusion & Impact:Conclusion: It can be concluded that both PP/BG ve PP/BG/ GTR is effective in treating Class II furcation defects however, GTR increases the regenerative potential with respect to new bone formation.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Karşılaştırmalı çalışma · Modeller · hayvan

Abstract

Aim: The purpose of this study is to compare clinical and histomorphometric effectiveness of platelet pellet/bioaktive glass (PP/BG) and platelet pellet/bioaktive glass/guided tissue regeneration (PP/BG/GTR) in treating Class IIfurcation defects in dogs and to examine the role of GTR in promoting the positive results. Metarial ard Mettods: Class II furcation lesions (5mm in height, 2 mm in depth) were surgically created on the buccal surface of second, third, and fourth premolars of two quadrants in the maxilla in three adult mongrel dogs weighing about 10 kg. After 5 weeks, right third and fourth premolars received PP/BG, left premolars received PP/BG/GTR. Right-left first premolars were used as control group. Clinical analysis included plaque index (PI), gingival index (GI), probing pocket depth (PPD), and clinical attachment loss (CAL), histometric anaysis included new sement and alveolar bone formation measurements. Results: Decrease in PI and GI were similar among all groups (p=0.770) while decrease in PPD and CAL scores in experimental groups were significantly greater than control group (p=0.004) with no significant differences between experimental groups (p=0.589). New sement formation was similar between experimental groups (p=0.37) while new bone formation in PP/BG/GTR group was greater than that in PP/BG group (p<0.001). Conclusion: It can be concluded that both PP/BG ve PP/BG/ GTR is effective in treating Class II furcation defects however, GTR increases the regenerative potential with respect to new bone formation.

Özet

Amaç: Bu çalışmanın amacı; köpeklerde oluşturulan Sınıf II furkasyon defektlerinin tedavisinde platelet pellet/bioaktif cam (PP/BC) ile platelet pellet/bioaktif cam/yönlendirilmiş doku rejenerasyonu (PP/BC/YDR) kombinasyonlarının rejeneratif etkinliğini klinik ve histomorfometrik olarak karşılaştırarak elde edilen pozitif sonuçlarda YDR'nin rolünü ortaya koymaktır. Gereç ve Yöntem: 10 kg ağırlığında üç adet erişkin mongrel tip köpeğin üst iki yarım çenesinde 2., 3. ve 4. premolar dişlerin bukkal yüzeylerinde Sınıf II furkasyon def ekti (5mm yükseklikte, 2mm derinlikte) oluşturuldu. İlk operasyondan 5 hafta sonra, sağ yarım çenedeki 3. ve 4. premolar dişlere PP/ BC, sol yarım çenedeki 3. 4. premolarlara PP/BC/YDR uygulandı. Sağ-sol l.premolar dişler kontrol grubu olarak kullanıldı. Klinik inceleme kapsamında; plak indeksi (Pİ), gingival indeks (Gİ), sondalanabilir cep derinliği (SCD) ve klinik ataş-man kaybı (KAK), histomorfometrik analiz kapsamında; yeni sement ve kemik miktarı ölçüldü. Bulgular: Deney periyodu sonunda Pİ ve Gİ değerlerin-deki azalmanın gruplar arasında farklılık göstermediği saptandı (p=0.770). SCD ve KAK değerlerindeki azalmanın ise deney gruplarında kontrol grubuna göre daha fazla olduğu (p=0.004), ancak iki deney grubu arasında farklılık olmadığı bulundu (p=0.589). Deney grupları karşılaştırıldığında yeni sement oluşumunun benzer olduğu (p=0.37) ancak yeni kemik miktarının PP/BC/YDR grubunda PP/BC grubuna göre istatistiksel anlamlı fazla olduğu (p<0.001) saptandı. Sonuç; PP/BC ve PP/BC/YDR uygulamasının Sınıf II furkasyon defektlerinin tedavisinde etkili olduğu ancak YDR uygulamasının kemik oluşumu açısından rejeneratif potansiyeli daha fazla arttırdığı düşünülmektedir.

🔖

Cite This Article

ÇETİNKAYA, B. Ö., KELEŞ, G. Ç., BARIŞ, S., GÜRGÖR, P. N. (2008). Cilinical and histomorphometric comparison of platet pellet/biactive glass combination with or without GTR in the treatment of class II furcation defects in dogs. Ondokuz Mayıs Üniv. Diş Hekimliği Derg., Cilt: 9 - Sayı: 1, 1–9. https://ajindex.com/articles/293173

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (1)

  1. Offenbacher S. Periodontal diseases: pathogenesis. Ann Periodontol. 1996; 1: 821-78. 2.Socransky SS, Haffajee AD. The nature of periodontal diseases. Ann Periodontol 1997.; 2: 3-10. 3.Flemmig TF. Periodontitis. Ann Periodontol. 1999; 4: 32-8. 4.Park JS, Suh JJ, Choi SH ve ark. Effects of pretreat-ment clinical parameters on bioactive glass implantation in intrabony periodontal defects. J Periodontol. 2001; 72 730-40. 5.Sculean A, Barbe G, Chiantella GC, Arweiler NB, Berakdar M, Brecx M. Clinical evaluation of an enamel matrix protein derivative combined with a bioactive glass for the treatment of intrabony periodontal defects in humans. J Periodontol. 2002; 73: 401-8. 6.Laurell L, Gottlow J, Zybutz M, Persson R. Treatment of intrabony defects by different surgical procedures. A literature review. J Periodontol. 1998; 69: 303-13. 7.Trejo PM, Weltman R, Caffesse R. Treatment of int-raosseous defects with bioabsorbable barriers alone or in combination with decalcified freeze-dried bone allog-raft: a randomized clinical trial. J Periodontol. 2000; 71: 1852-61. 8.Hanna R, Trejo PM, Weltman RL. Treatment of intrabony defects with bovine-derived xenograft alone and in combination with platelet-rich plasma: a randomized clinical trial. J Periodontol. 2004; 75: 1668-77. 9.Demir B, Demiralp B, Güncü GN, Uyanık MO, Çağlayan F. Intentional replantation of a hopeless tooth with the combination of platelet rich plasma, bioactive glass graft material and non-resorbable membrane: a case report. Dent Traumatol. 2007; 23:190-4. 10.Camargo PM, Lekovic V, Weinlaender M, Vasilic N, Madzarevic M, Kenney EB. Platelet-rich plasma and bovine porous bone mineral combined with guided tissue regeneration in the treatment of intrabony defects in humans. J Periodontal Res. 2002; 37: 300-6. 11.Lekovic V, Camargo PM, Weinlaender M, Vasilic N, Kenney EB. Comparison of platelet-rich plasma, bovine porous bone mineral, and guided tissue regeneration versus platelet-rich plasma and bovine porous bone mineral in the treatment of intrabony defects: a reentry study. J Periodontol. 2002; 73: 198-205. 12.Camargo PM, Lekovic V, Weinlaender M, Vasilic N, Madzarevic M, Kenney EB. A reentry study on the use of bovine porous bone mineral, GTR, and platelet-rich plasma in the regenerative treatment of intrabony defects in humans. Int J Periodontics Restorative Dent. 2005; 25: 49-59. 13.Keleş GÇ, Çetinkaya BÖ. Rejeneratif periodontal tedavide plateletten zengin plazmanın yeri. Türk Dişhek Der. 2007; 1