Journals / İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi / 2011 / Cilt: 1 - Sayı: 2

An evaluation of childhood infection related nephrectomies and the prevalence of xanthogranulomatous pyelonephritis

Pediatrik olgularda enfeksiyonla ilişkili nefrektomilerin irdelenmesi ve ksantogranülomatöz pyelonefrit prevalansı

Pages
75–78
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In addition it was conclude the reason of higher XGP percentage in our series.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:OBJECTIVE: We aimed to evaluate the childhood infection related nephrectomy reasons and to determine the frequency of xanthogranulomatous pyelonephritis (XGP).
📊
Key Findings & Data:METHODS: We retrospectively reviewed 56 pediatric patients who underwent nephrectomy secondary to chronic pyelonephritis between 1991 and 2010 at Izmir Dr.Behcet Uz children’s Hospital.
💡
Conclusion & Impact:In addition it was conclude the reason of higher XGP percentage in our series.
🔬Design:Review & Systematic Survey
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

OBJECTIVE: We aimed to evaluate the childhood infection related nephrectomy reasons and to determine the frequency of xanthogranulomatous pyelonephritis (XGP). METHODS: We retrospectively reviewed 56 pediatric patients who underwent nephrectomy secondary to chronic pyelonephritis between 1991 and 2010 at Izmir Dr.Behcet Uz children’s Hospital. Size and weight of kidneys, findings of radiological and scintigraphic investigations, presence of urinary infection at operation time, age and sex of patients and the relationship of these parameters were assessed. RESULTS: This series consisted of 35 boys (62.5%) and 21 girls (37.5%) with mean age of 3.05 years (6 months- 10 years). All patients present the loss of renal function more than 90- 95 percent detected by the radiological and scintigraphic evaluation. XGP was found in 9 cases (16.1%). Specific etiologic agents were not isolated in none of them. There are congenital predispositions such as ureteropelvic reflux or obstruction in 14 cases (25%). While kidney was large in 77.8% of XGP, was normal or small in 70.2% of other cases. Urinary infection was determined in 26 cases (46.4%). Hipertrophy of kidney was associated with the presence of XGP by both Chi-square test (p=0,021) and Spearman correlation analyses (p=0.019). CONCLUSION: In the present study, a realistic comprehensive picture of the nephrectomy secondary to infection has been provided. Then it was discussed if prevention nephrectomy in these disorders with early diagnosis and adequate medical treatment could be possible. In addition it was conclude the reason of higher XGP percentage in our series.

Özet

AMAÇ: Bu çalışmada enfeksiyona sekonder renal fonksiyonlarda şiddetli kayıp nedeniyle yapılan pediatrik nefrektomilerin değerlendirilmesi ve ksantogranülomatöz pyelonefrit (XGP) prevalansının belirlenmesi amaçlanmıştır. YÖNTEMLER: İzmir Dr. Behçet Uz Çocuk Hastanesinde 1991 ile 2010 yılları arasında kronik pyelonefrite bağlı renal fonksiyon kaybı nedeniyle nefrektomi uygulanan 56 olgu retrospektif olarak incelenmiştir. Böbrek boyutu ve ağırlığı, radyolojik ve sintigrafik inceleme bulguları, operasyon anında üriner enfeksiyon varlığı, olguların yaşı, cinsi ve tüm bu parametrelerin birbiriyle ilişkisi değerlendirilmiştir. BULGULAR: Olguların 35’i erkek (% 62,5) 21’i kız(%37,5) olup ortalama yaş 3,05 (6 ay- 10 yıl) bulunmuştur. Ksantogranülomatöz Pyelonefrit 9 olguda (%16,1) saptanmıştır. Bunların hiçbirinde spesifik etken bulunmamıştır. 14 olguda (% 25) kronik pyelonefrite predispozisyon yaratacak uretero-pelvik darlık ya da veziko-üreteral reflü benzeri konjenital bir patoloji mevcuttur. XGP saptanan olguların %77,8’inde böbrek büyük iken diğer olguların %70, 2’sinde böbrek boyutu normal ya da küçüktür. 26 olguda (%46,4) operasyon anında üriner enfeksiyon mevcuttur. Ki-kare testi ve Spearman Korelasyon analizlerinde renal hipertrofi ile XGP varlığı arasında anlamlı ilişki saptanmıştır (p=0,024 ve p=0,019). SONUÇ: Bu çalışmada çocukluk çağında enfeksiyona sekonder nefrektomi olgularının kapsamlı profili çıkartılmıştır. Erken tanı ve uygun tıbbi tedaviyle nefrektominin önlenilebilirliği sorgulanmıştır. Ek olarak XGP olgularının serimizdeki yüksek oranının nedenleri tartışılmıştır.

🔖

Cite This Article

ÜNLÜ, A. G. D., AKTAŞ, S., ORTAÇ, R., KAYHAN, A., ERGİN, M., SERDAROĞLU, E., BAK, M. (2011). An evaluation of childhood infection related nephrectomies and the prevalence of xanthogranulomatous pyelonephritis. İzmir Dr. Behçet Uz Çocuk Hastanesi Dergisi, Cilt: 1 - Sayı: 2, 75–78. https://ajindex.com/articles/268740

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (8)

  1. Mnttioli Cj. Pini-Prato A, Coslanzo S, Avanzini S, Rossi V, Basile A, Glıiggeri GM, Magnasco A, Leggio S, Rapuzzi G,.lasonııi V. Nephrectomy for multicyslİc dysplaslic kidney and renal hypodysplasia in children: where do we stand? Pediatr Surg hit 2010
  2. 26(5):523-8. http://dx.doi.org/10. i 007/s003S3-010-2592-7 PMid:20339S52 2. T horu p.1, Jokcla R, Cortes D, Nielsen OH. The results of 15 years of consistent strategy in treating ante nal ally suspected pelvi-ureteric junction obstruction. BJU hit 2003
  3. 91(9):S50-2. http://dx.doi.org/ 10.1046/j. 1464-410X.2003.04228.X PMid: 12780S46 3. Chabchoub K, Fakhfakh H, Kanoun S, Bahloul A, Mhiri MN. Childhood nephrectomy indications: a changing profile. Tunis Med 2010
  4. 88(7):474-7. PMid:20582882 4. Leumann EP, Egli F, Fanconi A, Guignard.IP, Koegel R, Oetliker O, Paunier L. Outcome of pediatric patients with end-stage renal disease in Switzerland 1973-1982. hit J Pediatr Nephrol 1984:5(3):155-S. PMid:6500810 5. Aziz MA, Hossain AZ. Banu T, Karim MS, islam N, Sultana H.Alam Ml, Hanif A, Khan AR. In hydronephrosis less than 10% kidnev function is not an indication for nephrectomy in children. Eur J Pediatr Surg 2002
  5. 12{5):304-7. http://dx.doi.org/10.l055/s-2002-35956 PMid: 12469255 6. Hammad FT Upadhyay V. Indications for nephrectomy in children: what has changed? J Pediatr Urol 2006
  6. 2(5):430-5. http://dx.doi.org/10.10l6/j-jpurol.2005.09.009 PMid: 18947651 7. S locker.IT. Appendices. In S locker JT, Dehner LP, ed. Pediatric Pathology. Vol 2. Philadelphia: Lippincoll, 2001. 8. Lac son A, Bernstein J, Risdon RA, Gilbert-Barnes E. Renal System: Kidney and urinary tract. In: Gil bert-Barnes E, ed. Potter's Pathol o ay of the fetus and infant, vol 2. II. Ed. St. Louis: Mosby-Elsevier, 2007: 1281-1344. 9. Husain AN, Pyshcr-TJ, Dehner LP. The kidney and lower urinary tract. In: St&cker JT, Dehner LP, cd. Pediatric pathology, 2nd ed, vol 2. Philadelphia: Lippincott, 2001. 10. Nercus W. Gunthcr IV, Lockatcll V, Johnson DE, Mobley HLT. In Vivo Dynamics of Type 1 fimbria Regulation in Uropathogenic Escherichia coli during Experimental Urinary Tract Infection. Infection and Immunity 2001
  7. 69(5):2838-2846. http://dx.doi.org/10.1128/1A 1.69.5.2838-2846.2001 PMid: 11292696 PMCid:98232 11. Connell H, Poulsen LK, Klemm P. Expression of type 1 and P fimbriae in situ and localisation of a uropalhogenic Escherichia coli strain in the murine bladder and kidney, hit J Med Microbiol 2000
  8. 290(7):587-97. PMid: 11200540 12. Snyder JA, Hau