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Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2019 / Cilt: 29 - Sayı: 1

Organ Transplantation in the Turkey and the World

Türkiye ve Dünyada Organ Transplantasyonu

AYŞE GÜLDEN DİNİZ ÜNLÜ
Cem TUĞMEN
İsmai̇l SERT
Pages
1–10
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review; historical development of transplantation in Turkey and in the world, transplantation pathology and rejection evaluation criteria are briefly reviewed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Organ transplantation significantly changed the life expectancy and quality of life of patients with advanced organ failure.
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Key Findings & Data:Solid organ transplantation techniques which had been used experimentally in animals until the middle of the twentieth century, have become a treatment option in the 21st century.
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Conclusion & Impact:In this review; historical development of transplantation in Turkey and in the world, transplantation pathology and rejection evaluation criteria are briefly reviewed.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Organ transplantation significantly changed the life expectancy and quality of life of patients with advanced organ failure. Solid organ transplantation techniques which had been used experimentally in animals until the middle of the twentieth century, have become a treatment option in the 21st century. With the discovery of new drugs that suppress immunity in the 1960s, transplantation has gained significant momentum. In this review; historical development of transplantation in Turkey and in the world, transplantation pathology and rejection evaluation criteria are briefly reviewed.

Özet

Organ nakli, ileri organ yetmezliği olan hastaların yaşam süresi ve yaşam kalitesini önemli ölçüde değiştirmiştir. Yirminci yüzyılın ortasına dek deney hayvanlarında bilimsel araştırma niteliğinde uygulanan solid organ transplantasyon teknikleri, 21. yüzyılda insanda bir tedavi seçeneği haline gelmiştir. 1960’larda bağışıklığı baskılayan yeni ilaçların keşfi ile transplantasyon ciddi bir ivme kazanmıştır. Bu derlemede; Türkiye ve dünyada transplantasyonun tarihsel gelişimi, transplantasyon patolojisi ve rejeksiyon değerlendirme kriterleri kısaca gözden geçirilmiştir

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Cite This Article

ÜNLÜ, A. G. D., TUĞMEN, C., SERT, İ. (2019). Organ Transplantation in the Turkey and the World. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 29 - Sayı: 1, 1–10. https://ajindex.com/articles/192737

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References (9)

  1. Ruiz P. Transplantation pathology. Cambridge University Press 2018: United Kingdom, 2. Edition: Chapter 1: p.1-24. Murray J. Interview with Dr Joseph Murray (by Francis L Delmonico). Am J Transplant. 2002;2(9):803-6.
  2. Black CK, Termanini KM, Aguirre O, Hawksworth JS, Sosin M. Solid organ transplantation in the 21st century. Ann Transl Med. 2018;6(20):409. Haberal M. Historical evolution of kidney and liver transplantation in Turkey. Transplant Proc. 1995;27(5):2771-4. http://organ.saglik.gov.tr (07.01.2019).
  3. Zeytunlu M, Uğuz A, Ünalp Ö, Ergün O, Karasu Z, Günşar F et al, Results of 1001 liver transplantations in 23 years: Ege University experience. Turk J Gastroenterol. 2018; 29(6):664- 668. Tuğmen C, Baran M, Sert İ, Anıl AB, Kebapçı E, Doğan SM, et al. Pediatric small bowel transplantation: A single-center experience from Turkey. Turk J Gastroenterol. 2016; 27(5):428-32. Choo SY. Immunogenetics of the HLA system. Yonsei Med J. 1991;32(1):1-8. https://doi.org/10.3349/ymj.1991.32.1.1 PMID: 1908609. Rock KL, Reits E, Neefjes J. Present Yourself! By MHC Class I and MHC Class II Molecules. Trends Immunol. 2016;37(11):724-37.
  4. Schultz KR, Bader S, Nelson D, Wang MD, HayGlass KT. Immune suppression by lysosomotropic amines and cyclosporine on T-cell responses to minor and major histocompatibility antigens: does synergy exist? Transplantation. 1997 15;64(7):1055-65. PMID: 9381529. Salehi S, Reed EF. The divergent roles of macrophages in solid organ transplantation. Curr Opin Organ Transplant. 2015;20(4):446-53.
  5. Benichou G, Yamada Y, Aoyama A, Madsen JC. Natural killer cells in rejection and tolerance of solid organ allografts. Curr Opin Organ Transplant. 2011;16(1):47-53.
  6. Zhang Q, Reed EF. Non-MHC antigenic targets of the humoral immune response in transplantation. Curr Opin Immunol. 2010;22(5):682-8. https://tpis.upmc.com/(07.01.2019)
  7. Roufosse C, Simmonds N, Clahsen- van Groningen M. Haas M, Henriksen KJ, Horsfield C. et al. A 2018 reference guide to the Banff Classification of renal allogreft pathology. Transplantation. 2018;102:1795-1814.
  8. Stefoni S, Campieri C, Donati G, Orlandi V. The history of clinical renal transplant. J Nephrol. 2004;17(3):475-8. PMID: 15365975. Danovitch GM, Cohen DJ, Weir MR, Stock PG, Bennett WM, Christensen LL, Sung RS. Current status of kidney and pancreas transplantation in the United States, 1994-2003. Am J Transplant. 2005;5(4 Pt 2):904-15.
  9. Joshi A, Oyer PE, Berry GJ, Billingham ME. Heart-lung transplantation: Cardiac clinicopathol