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Journals / İzmir Tepecik Eğitim Hastanesi Dergisi / 2015 / Cilt: 25 - Sayı: 2

Pathological outcomes of gender differences in the diagnosis of primer bladder cancer

Primer mesane kanseri tanısında cinsiyet farklılığının patolojik sonuçları

Rahmi Gökhan EKİN
Zübeyde EKİN YILDIRIM
Gökhan KOÇ
AYŞE GÜLDEN DİNİZ ÜNLÜ
Yusuf Özlem İLBEY
Ferruh ZORLU
Pages
89–92
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Also, high grade tumor is more frequent in men.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We aimed to examine the impact of gender differences on tumor stage retrospectively in a single-centered study.
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Key Findings & Data:Methods: 470 patients who underwent transurethral resection for the first time between January 2010-January 2015 were examined retrospectively.
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Conclusion & Impact:Also, high grade tumor is more frequent in men.
🔬Design:Research Article
📍Scope:2010 Verileri
⚙️Variables:Domain Parameters

Abstract

Objective: We aimed to examine the impact of gender differences on tumor stage retrospectively in a single-centered study. Methods: 470 patients who underwent transurethral resection for the first time between January 2010-January 2015 were examined retrospectively. Age, gender, smoking habbits, presence of gross hematuria, the first episode of gross hematuria, and time from the first episode of hematuria to the diagnosis of the bladder cancer, stage and grade of the tumor were evaluated. Results: 450 patients (male, n=376; 83.5%, and female, n=74; 16.5%) were included in this study. (p<0.5) Distribution of tumour grades was analyzed In men pTa (59.9%; n=225) vs 51.4%; n=38), p<0.05), and pT1 (29.8%; n=112) vs. 25.7%; n=19), p<0.05) were statistically significant more frequent while in women pT2 (10.3%; n=39) vs 22.9% (n=17), p<0.05) was statistically significantly more frequent. Conclusion: While non- muscle invasive bladder cancer is seen more frequently in men, muscle invasive bladder cancer is observed more frequently in women. Also, high grade tumor is more frequent in men.

Özet

Amaç: Cinsiyet farklılığının primer mesane kanserinde tümör evresine etkisini, geriye dönük ve tek merkezli olarak araştırılması amaçladık. Yöntemler: Ocak 2010 ile Ocak 2015 arasında ilk defa transüretral rezeksiyon yapılan 470 hastanın hepsi geriye dönük olarak incelendi. Çalışmada yaş, cinsiyet, sigara alışkanlığı, makroskopik hematüri varlığı, ilk makroskopik hematüri zamanı ile tanıya kadar geçen zaman, tümör evresi ve tümör derecesi değerlendirildi. Bulgular: Çalışmaya 450 hasta dâhil edildi. Hastaların 376’sı (%83,5) erkek ve 74’ü (%16,5) kadın idi (p<0,05). Tümör evresi dağılımı, erkeklerde pTa (%59,9 (n=225) vs. %51,4 (n=38), p<0,05) ve pT1 (%29,8 (n=112) vb. %25,7 (n=19), p<0,05) daha sık iken, kadınlarda pT2 (%10,3 (n=39) vs. %22,9 (n=17), p<0.05) daha sık tespit edildi. Yüksek dereceli tümör görülme oranı erkeklerde %69,9 (n=263) ve kadınlarda %56,7 (n=42) olup, istatistiksel olarak anlamlı olarak erkeklerde daha fazla idi (p<0,05). Sonuç: Kas invaziv olmayan mesane kanseri erkek cinsiyetinde sık görülürken, kadın cinsiyetinde kas invaziv mesane kanseri daha sık görülür. Ayrıca, erkek cinsiyetinde yüksek dereceli tümör daha sıktır.

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Cite This Article

EKİN, R. G., YILDIRIM, Z. E., KOÇ, G., ÜNLÜ, A. G. D., İLBEY, Y. Ö., ZORLU, F. (2015). Pathological outcomes of gender differences in the diagnosis of primer bladder cancer. İzmir Tepecik Eğitim Hastanesi Dergisi, Cilt: 25 - Sayı: 2, 89–92. https://ajindex.com/articles/210964

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