Journals / Glokom Katarakt / 2010 / Cilt: 5 - Sayı: 1

Primer açık açılı Glokomu olan bir olguda tamoksifen ile meme kanseri tedavisi esnasında bilateral göz içi basıncı yükselişi

Bilateral intraocular pressure rise during the therapy of breast cancer by tamoxifen in a patient with primary open angle Glaucoma

Pages
51–53
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Here, we aim to attract attention among ophthalmologists and oncologists a possible adverse effect of tamoxifen therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Tamoxifen is an anti-estrogen agent used in therapy of the breast cancer.
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Key Findings & Data:We report a case of bilateral intraocular pressure rise observed during tamoxifen therapy in a 50-yearold woman with primary open angle glaucoma which has not been previously reported.
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Conclusion & Impact:Here, we aim to attract attention among ophthalmologists and oncologists a possible adverse effect of tamoxifen therapy.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Tamoxifen is an anti-estrogen agent used in therapy of the breast cancer. A number of ocular complications such as maculopathy have been described secondary to tamoxifen therapy. We report a case of bilateral intraocular pressure rise observed during tamoxifen therapy in a 50-yearold woman with primary open angle glaucoma which has not been previously reported. Rapid decline of intraocular pressure in both eyes was achieved by means of cessation of tamoxifen and administered oral acetazolamide therapy. Here, we aim to attract attention among ophthalmologists and oncologists a possible adverse effect of tamoxifen therapy.

Özet

Tamoksifen meme kanseri tedavisinde kullanılan antiöstrojen bir ajandır. Tamoksifene bağlı makülopati gibi birtakım oküler komplikasyonlar tanımlanmıştır. Biz primer açık açılı glokomu olan 50 yaşında bir kadın olguda tamoksifen ile meme kanseri tedavisi esnasında bilateral göz içi basıncı yükselişini sunacağız. Bu durum daha önce bildirilmemiştir. Tamoksifenin kesilmesi ve oral asetazolamid tedavisi başlanmasıyla her iki gözde de hızlı göz içi basıncı düşüsü elde edildi. Biz burada göz ve onkoloji hekimleri arasında tamoksifen tedavisinin olası bir beklenmeyen etkisi hakkında dikkat çekmek istiyoruz.

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Cite This Article

ÖZCURA, F., GUIOCHET, N., CROZAFON, P., HERY, M. (2010). Primer açık açılı Glokomu olan bir olguda tamoksifen ile meme kanseri tedavisi esnasında bilateral göz içi basıncı yükselişi. Glokom Katarakt, Cilt: 5 - Sayı: 1, 51–53. https://ajindex.com/articles/226549

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