Journals / Güncel Retina Dergisi / 2018 / Cilt: 2 - Sayı: 2

Systemic and Genetic Risk Factors in Diabetic Retinopathy and Diabetic Macular Edema

Diyabetik Retinopati ve Diyabetik Maküler Ödem’de Sistemik ve Genetik Risk Faktörleri

Pages
102–107
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, we have summarized the known systemic risk factors as well as the genetic basis of the disease under the light of genetic studies

📌 3 Key Takeaways

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Objective & Hypothesis:Diabetic retinopathy (DR) is an increasingly common health problem in our country as it is all over the world.
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Key Findings & Data:It is important to increase the understanding of these responsible risk factors and develop preventive strategies.
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Conclusion & Impact:In this review, we have summarized the known systemic risk factors as well as the genetic basis of the disease under the light of genetic studies
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Diabetic retinopathy (DR) is an increasingly common health problem in our country as it is all over the world. DR is a leading cause of loss of vision patients at productive age. Current treatment of diabetic macular edema (DME) is distressing, expensive and not suitable for some patient subgroups. For this reason, the development and progression of DR and DME are affected by many systemic risk factors. It is important to increase the understanding of these responsible risk factors and develop preventive strategies. However, the presence of systemic risk factors is inadequate to predict the progression of the disease on an individual basis. It indicates the presence of a genetic effect. In this review, we have summarized the known systemic risk factors as well as the genetic basis of the disease under the light of genetic studies

Özet

Diyabetik retinopati (DR) bütün dünyada olduğu gibi ülkemizde de artan yaygın bir sağlık sorunudur. Üretken yaş grubundaki kişiler arasında görsel kayıpların önde gelen nedenidir. Diyabetik maküler ödemin (DMÖ) güncel tedavisi sıkıntılı, pahalı ve ayrıca bazı hasta alt grupları için uygun olmamaktadır. Bu nedenle DR ve DMÖ'in gelişme ve progresyonu birçok sistemik risk faktöründen etkilenmektedir. Bu sorumlu risk faktörlerinin anlaşılmasını arttırmak ve önleyici stratejiler geliştirmek önemlidir. Buna karşın sistemik risk faktörlerinin varlığı bireysel bazda hastalığın progresyonunu tahmin etmede yetersiz kalmaktadır. Bu durum genetik bir etkinin varlığını işaret etmektedir. Bu çalışmada bilinen sistemik risk faktörlerini ve ayrıca genetik çalışmaların ışığı altında hastalığın genetik zeminini gözden geçirdik

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Cite This Article

DEMİRCAN, S., PANGAL, E. (2018). Systemic and Genetic Risk Factors in Diabetic Retinopathy and Diabetic Macular Edema. Güncel Retina Dergisi, Cilt: 2 - Sayı: 2, 102–107. https://ajindex.com/articles/224251

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