Journals / Güncel Retina Dergisi / 2021 / Cilt: 5 - Sayı: 2

Dyschromatopsy, Achromatopsia and Blue Cone Monochromatism; Pathophysiology, Clinical Findings, Diagnosis and Treatmentand Treatment

Diskromatopsi, Akromatopsi ve Mavi Kon Monokromatizmi; Patofizyoloji, Klinik Bulgular, Tanı ve Tedavi

Pages
159–164
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Although it can be easily diagnosed with color vision tests and electrophysiological tests, current treatment options are limited and its success rate is low.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Color vision is a complex perception caused by the stimulation of cone photoreceptors in the retina and the perception of this stimulation in the brain.
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Key Findings & Data:Hereditary color vision deficiencies are caused by a defect in the functions of cone cells.
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Conclusion & Impact:Although it can be easily diagnosed with color vision tests and electrophysiological tests, current treatment options are limited and its success rate is low.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Color vision is a complex perception caused by the stimulation of cone photoreceptors in the retina and the perception of this stimulation in the brain. Hereditary color vision deficiencies are caused by a defect in the functions of cone cells. Color vision deficiencies are named according to three different types of pigments contained in cones. These disorders, which are seen in high prevalence in worldwide, are found more frequently in male. Contrary to thought, colored vision defects often affect daily life. Although it can be easily diagnosed with color vision tests and electrophysiological tests, current treatment options are limited and its success rate is low.

Özet

Renkli görme, retinadaki koni fotoreseptörlerinin uyarılması ve bu uyarının beyinde algılanması ile oluşan karmaşık bir algıdır. Kalıtsal renkli görme kusurları koni hücrelerinin fonksiyonlarındaki bozukluk sonucu oluşur. Renkli görme bozuklukları konilerin içerdiği üç farklı pigment tipine göre adlandırılır. Dünya genelinde yüksek prevalansta görülen bu bozukluklar, erkeklerde daha sık saptanmaktadır. Düşünülenin aksine renkli görme kusurları günlük hayatı sıklıkla etkiler. Tanı renkli görme testleri ve elektrofizyolojik testler ile kolaylıkla konabilmekle beraber günümüzde tedavi seçenekleri sınırlı ve başarı oranı düşüktür.

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Cite This Article

SIRAKAYA, E., ATAŞ, M. (2021). Dyschromatopsy, Achromatopsia and Blue Cone Monochromatism; Pathophysiology, Clinical Findings, Diagnosis and Treatmentand Treatment. Güncel Retina Dergisi, Cilt: 5 - Sayı: 2, 159–164. https://ajindex.com/articles/219681

References (10)

  1. Birch J. A practical guide for colour-vision examination: report of the Standardization Committee of the International Research Group on Colour-Vision Deficiencies. Ophthalmic Physiol Opt [Internet] 1985;5(3):265–85. C. D. No Title. In: Ryan’s Retina. Vol 1. 6th ed. Philadelphia: Elsevier/ Saunders; Fuortes MGF, Gunkel RD, Rushton WAH. Increment thresholds in a subject deficient in cone vision. J Physiol [Internet] 1961;156(1):179–92. Procedures for Testing Color Vision. National Academies Press; 1981.
  2. Crognale MA, Teller DY, Yamaguchi T, Motulsky AG, Deeb SS. Analysis of red/green color discrimination in subjects with a single X- linked photopigment gene. Vision Res 1999;39(4):707–19.
  3. Neitz M, Neitz J. Molecular genetics of color vision and color vision defects. Arch Ophthalmol 2000;118(5):691–700. Post RH. Population differences in red and green color vision deficiency: a review, and a query on selection relaxation. Eugen Q 1962;9:131–46.
  4. Nathans J, Piantanida TP, Eddy RL, Shows TB, Hogness DS. Molecular genetics of inherited variation in human color vision. Science (80- ) 1986;232(4747):203–10.
  5. Nathans J, Hogness DS. Isolation and nucleotide sequence of the gene encoding human rhodopsin. Proc Natl Acad Sci U S A 1984;81(15 I):4851–5. Schefrin BE. Diagnosis of Defective Colour Vision, by Jennifer Birch, Oxford University Press, New York, 1993, Paperback, 187 pp. Color Res Appl [Internet] 1994;19(6):484–484.
  6. Weitz CJ, Miyake Y, Shinzato K, Montag E, Zrenner E, Went LN, et al. Human tritanopia associated with two amino acid substitutions in the blue- sensitive opsin. Am J Hum Genet 1992;50(3):498–507.
  7. Regan BC, Reffin JP, Mollon JD. Luminance noise and the rapid determination of discrimination ellipses in colour deficiency. Vision Res 1994;34(10):1279–99.
  8. STEWARD JM, COLE BL. What Do Color Vision Defectives Say About Everyday Tasks? Optom Vis Sci [Internet] 1989;66(5):288–95. Dain SJ. Daylight simulators and colour vision tests. Ophthalmic Physiol Opt 1998;18(6):540–4. Birch J. Efficiency of the Ishihara test for identifying red-green colour deficiency. Ophthalmic Physiol Opt 1997;17(5):403–8.
  9. Stager DR, Everett M, Swanson WH. The importance of controlled illumination in color vision testing in a pediatric ophthalmology clinical practice. J Pediatr Ophthalmol Strabismus. 1993; 30(1): 39-42.
  10. Swanson WH, Cohen JM. Color vision. Ophthalmol. Clin. North Am.2003;16(2):179–203. Cole BL. Assessment of inherited colour vision defects in clinical practice. Clin. Ex